KEGG   PATHWAY: bcs00230
Entry
bcs00230                    Pathway                                
Name
Purine metabolism - Brucella canis ATCC 23365
Class
Metabolism; Nucleotide metabolism
Pathway map
bcs00230  Purine metabolism
bcs00230

Module
bcs_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bcs00230]
bcs_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bcs00230]
bcs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bcs00230]
bcs_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bcs00230]
bcs_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bcs00230]
bcs_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bcs00230]
bcs_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bcs00230]
Other DBs
GO: 0006163 0042278
Organism
Brucella canis ATCC 23365 [GN:bcs]
Gene
BCAN_A0059  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BCAN_A0180  rdgB; non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BCAN_A0197  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BCAN_A0198  cysN; sulfate adenylyltransferase, large subunit [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BCAN_A0271  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BCAN_A0272  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BCAN_A0273  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BCAN_A0354  [KO:K14977] [EC:3.5.3.26]
BCAN_A0355  [KO:K16842] [EC:3.5.2.5]
BCAN_A0357  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BCAN_A0358  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BCAN_A0362  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BCAN_A0419  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BCAN_A0450  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BCAN_A0469  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
BCAN_A0515  allA; Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BCAN_A0516  pucM; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BCAN_A0639  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BCAN_A0665  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BCAN_A0679  [KO:K06952] [EC:3.1.3.89]
BCAN_A0706  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BCAN_A0722  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BCAN_A0723  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BCAN_A0739  [KO:K00939] [EC:2.7.4.3]
BCAN_A0764  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BCAN_A0852  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269]
BCAN_A0855  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265]
BCAN_A0856  purS; phosphoribosylformylglycinamidine synthase, purS protein [KO:K23264]
BCAN_A0857  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BCAN_A0862  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BCAN_A0890  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BCAN_A0900  surE; acid phosphatase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BCAN_A1056  [KO:K00525] [EC:1.17.4.1]
BCAN_A1060  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BCAN_A1082  [KO:K04765] [EC:3.6.1.9]
BCAN_A1235  [KO:K00939] [EC:2.7.4.3]
BCAN_A1383  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BCAN_A1384  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BCAN_A1385  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BCAN_A1567  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BCAN_A1570  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BCAN_A1577  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BCAN_A1721  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BCAN_A1760  [KO:K09769] [EC:3.1.4.16]
BCAN_A1782  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BCAN_A1783  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BCAN_A1854  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BCAN_A2030  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BCAN_B0317  [KO:K00525] [EC:1.17.4.1]
BCAN_B0318  [KO:K00526] [EC:1.17.4.1]
BCAN_B0355  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BCAN_B0364  guaA; GMP synthase, C-terminal domain [KO:K01951] [EC:6.3.5.2]
BCAN_B0653  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
BCAN_B0683  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bcs00030  Pentose phosphate pathway
bcs00220  Arginine biosynthesis
bcs00250  Alanine, aspartate and glutamate metabolism
bcs00260  Glycine, serine and threonine metabolism
bcs00340  Histidine metabolism
bcs00630  Glyoxylate and dicarboxylate metabolism
bcs00730  Thiamine metabolism
bcs00740  Riboflavin metabolism
bcs00790  Folate biosynthesis
KO pathway
ko00230   

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