KEGG   PATHWAY: bspo00230
Entry
bspo00230                   Pathway                                
Name
Purine metabolism - Brevibacterium spongiae
Class
Metabolism; Nucleotide metabolism
Pathway map
bspo00230  Purine metabolism
bspo00230

Module
bspo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bspo00230]
bspo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bspo00230]
bspo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bspo00230]
bspo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bspo00230]
bspo_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bspo00230]
bspo_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bspo00230]
Other DBs
GO: 0006163 0042278
Organism
Brevibacterium spongiae [GN:bspo]
Gene
L1F31_02800  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
L1F31_06380  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
L1F31_03820  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
L1F31_03785  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
L1F31_06340  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
L1F31_03650  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
L1F31_03745  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
L1F31_03740  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
L1F31_03825  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
L1F31_07095  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
L1F31_07100  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
L1F31_17655  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
L1F31_06345  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
L1F31_12540  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
L1F31_05185  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
L1F31_13355  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
L1F31_10855  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
L1F31_07585  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
L1F31_05285  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
L1F31_13705  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
L1F31_13865  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
L1F31_08570  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
L1F31_06295  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
L1F31_04485  FAD binding domain-containing protein [KO:K13481] [EC:1.17.1.4]
L1F31_04490  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
L1F31_14415  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
L1F31_14410  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
L1F31_14405  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
L1F31_13690  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
L1F31_08240  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
L1F31_04500  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
L1F31_10120  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
L1F31_13145  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
L1F31_13140  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
L1F31_10515  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
L1F31_14120  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
L1F31_10255  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
L1F31_05470  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
L1F31_06450  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
L1F31_05705  RelA/SpoT domain-containing protein [KO:K07816] [EC:2.7.6.5]
L1F31_17110  RelA/SpoT domain-containing protein [KO:K07816] [EC:2.7.6.5]
L1F31_04305  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
L1F31_03490  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
L1F31_13085  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
L1F31_07820  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
L1F31_06075  adenylate kinase [KO:K00939] [EC:2.7.4.3]
L1F31_10305  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
L1F31_02940  GTP-binding protein [KO:K00956] [EC:2.7.7.4]
L1F31_02935  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
L1F31_04560  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
L1F31_04555  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
L1F31_04550  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
L1F31_06995  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
L1F31_04530  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
L1F31_04585  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
L1F31_18000  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bspo00030  Pentose phosphate pathway
bspo00220  Arginine biosynthesis
bspo00250  Alanine, aspartate and glutamate metabolism
bspo00260  Glycine, serine and threonine metabolism
bspo00340  Histidine metabolism
bspo00630  Glyoxylate and dicarboxylate metabolism
bspo00730  Thiamine metabolism
bspo00740  Riboflavin metabolism
bspo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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