KEGG   PATHWAY: bsr00230
Entry
bsr00230                    Pathway                                
Name
Purine metabolism - Bacillus subtilis subsp. subtilis RO-NN-1
Class
Metabolism; Nucleotide metabolism
Pathway map
bsr00230  Purine metabolism
bsr00230

Module
bsr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bsr00230]
bsr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bsr00230]
bsr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bsr00230]
bsr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bsr00230]
bsr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bsr00230]
Other DBs
GO: 0006163 0042278
Organism
Bacillus subtilis subsp. subtilis RO-NN-1 [GN:bsr]
Gene
I33_2434  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
I33_2421  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
I33_1058  alpha-phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
I33_0063  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
I33_0736  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
I33_0740  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
I33_0738  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
I33_0262  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
I33_0735  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
I33_0733  purS; phosphoribosylformylglycinamidine synthase, PurS protein [KO:K23264] [EC:6.3.5.3]
I33_0734  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
I33_0737  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
I33_0730  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
I33_0729  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
I33_0732  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
I33_0731  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
I33_0739  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
I33_2807  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
I33_3337  YunD [KO:K01081] [EC:3.1.3.5]
I33_2203  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
I33_1723  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
I33_0082  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
I33_0014  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
I33_2333  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
I33_2889  rdgB; hypothetical protein [KO:K01519] [EC:3.6.1.66]
I33_2267  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
I33_3351  pucD; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain, putative [KO:K00087] [EC:1.17.1.4]
I33_3352  pucC; putative xanthine dehydrogenase subunit C [KO:K00087] [EC:1.17.1.4]
I33_3350  pucE; [2Fe-2S] binding domain protein [KO:K00087] [EC:1.17.1.4]
I33_0720  hypothetical protein [KO:K01951] [EC:6.3.5.2]
I33_3306  guaC; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
I33_1481  cytidine/deoxycytidylate deaminase family protein [KO:K01487] [EC:3.5.4.3]
I33_1755  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
I33_1929  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
I33_1930  ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
I33_0021  Dgk [KO:K15518] [EC:2.7.1.113]
I33_2806  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
I33_1294  YjbM [KO:K07816] [EC:2.7.6.5]
I33_4002  YwaC [KO:K07816] [EC:2.7.6.5]
I33_4216  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
I33_0020  Dck [KO:K15519] [EC:2.7.1.76 2.7.1.74]
I33_1630  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
I33_0744  adenine deaminase [KO:K01486] [EC:3.5.4.2]
I33_0880  Ser/Thr protein phosphatase family protein [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
I33_1883  hypothetical protein [KO:K09769] [EC:3.1.4.16]
I33_0165  adenylate kinase [KO:K00939] [EC:2.7.4.3]
I33_1226  yisZ; sporulation putative adenylylsulfate kinase YisZ [KO:K00860] [EC:2.7.1.25]
I33_1747  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
I33_1746  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
I33_1227  yitA; sporulation putative sulfate adenylyltransferase YitA [KO:K00958] [EC:2.7.7.4]
I33_3345  pucL; uricase [KO:K16838] [EC:1.7.3.3 4.1.1.97]
I33_3346  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
I33_3341  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
I33_3356  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
I33_3355  purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
I33_3800  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
I33_3801  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
I33_3802  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bsr00030  Pentose phosphate pathway
bsr00220  Arginine biosynthesis
bsr00250  Alanine, aspartate and glutamate metabolism
bsr00260  Glycine, serine and threonine metabolism
bsr00340  Histidine metabolism
bsr00630  Glyoxylate and dicarboxylate metabolism
bsr00730  Thiamine metabolism
bsr00740  Riboflavin metabolism
bsr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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