KEGG   PATHWAY: bxb00330
Entry
bxb00330                    Pathway                                
Name
Arginine and proline metabolism - Paraburkholderia xenovorans LB400
Class
Metabolism; Amino acid metabolism
Pathway map
bxb00330  Arginine and proline metabolism
bxb00330

Module
bxb_M00015  Proline biosynthesis, glutamate => proline [PATH:bxb00330]
bxb_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:bxb00330]
bxb_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:bxb00330]
bxb_M00970  Proline degradation, proline => glutamate [PATH:bxb00330]
Other DBs
GO: 0006525 0006560
Organism
Paraburkholderia xenovorans LB400 [GN:bxb]
Gene
DR64_3694  amidohydrolase family protein [KO:K01485] [EC:3.5.4.1 3.5.4.21]
DR64_7640  amidohydrolase family protein [KO:K01485] [EC:3.5.4.1 3.5.4.21]
DR64_6422  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_4824  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_3637  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_5711  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_7744  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_8675  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_8740  hydantoinase/oxoprolinase family protein [KO:K01473] [EC:3.5.2.14]
DR64_6423  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_4823  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_3638  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_5712  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_7745  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_8676  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_8741  hydantoinase B/oxoprolinase family protein [KO:K01474] [EC:3.5.2.14]
DR64_1179  hypothetical protein [KO:K01584] [EC:4.1.1.19]
DR64_6267  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
DR64_7700  beta-eliminating lyase family protein [KO:K01581] [EC:4.1.1.17]
DR64_2737  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_5674  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_5676  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_8248  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_5670  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_4286  spermine/spermidine synthase family protein [KO:K00797] [EC:2.5.1.16]
DR64_6262  aminotransferase class-III family protein [KO:K12256] [EC:2.6.1.113]
DR64_6296  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4591  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_1101  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_1296  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_6799  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_6705  acyl-CoA reductase family protein [KO:K00128] [EC:1.2.1.3]
DR64_5051  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_8539  acyl-CoA reductase family protein [KO:K00128] [EC:1.2.1.3]
DR64_7727  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4103  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4478  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_2150  acetyltransferase domain protein [KO:K00657] [EC:2.3.1.57]
DR64_6842  FAD binding domain protein [KO:K00274] [EC:1.4.3.4]
DR64_6490  beta-eliminating lyase family protein [KO:K12252] [EC:2.6.1.84]
DR64_1139  speB; agmatinase [KO:K12255] [EC:3.5.3.7]
DR64_2006  amidase family protein [KO:K01426] [EC:3.5.1.4]
DR64_4255  amidase family protein [KO:K01426] [EC:3.5.1.4]
DR64_6379  amidase family protein [KO:K01426] [EC:3.5.1.4]
DR64_8562  amidase family protein [KO:K01426] [EC:3.5.1.4]
DR64_603  astA; arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
DR64_604  aruF; arginine/ornithine succinyltransferase, alpha subunit [KO:K00673] [EC:2.3.1.109]
DR64_601  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
DR64_605  astC; succinylornithine transaminase family protein [KO:K00840] [EC:2.6.1.81]
DR64_602  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
DR64_600  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
DR64_6256  FAD binding domain protein [KO:K09471] [EC:1.4.3.-]
DR64_6208  FAD binding domain protein [KO:K09471] [EC:1.4.3.-]
DR64_6816  FAD binding domain protein [KO:K09471] [EC:1.4.3.-]
DR64_6266  aldehyde dehydrogenase family protein [KO:K09472] [EC:1.2.1.99]
DR64_4871  aldehyde dehydrogenase family protein [KO:K09472] [EC:1.2.1.99]
DR64_5042  FAD binding domain protein [KO:K24954]
DR64_5040  FAD dependent oxidoreductase family protein [KO:K24955]
DR64_8635  FAD dependent oxidoreductase family protein [KO:K24955]
DR64_1658  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
DR64_6725  pyrroline-5-carboxylate reductase dimerization family protein [KO:K00286] [EC:1.5.1.2]
DR64_2228  delta-1-pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
DR64_2687  proB; glutamate 5-kinase [KO:K00931] [EC:2.7.2.11]
DR64_2752  proA; glutamate-5-semialdehyde dehydrogenase [KO:K00147] [EC:1.2.1.41]
DR64_4793  alpha/beta hydrolase fold family protein [KO:K01259] [EC:3.4.11.5]
DR64_6515  2OG-Fe(II) oxygenase superfamily protein [KO:K00472] [EC:1.14.11.2]
DR64_5688  2OG-Fe(II) oxygenase superfamily protein [KO:K00472] [EC:1.14.11.2]
DR64_1894  aminotransferase class IV family protein [KO:K00824] [EC:2.6.1.21]
DR64_6345  proline racemase [KO:K01777] [EC:5.1.1.4]
DR64_7069  ornithine cyclodeaminase/mu-crystallin family protein [KO:K19743] [EC:1.5.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
bxb00020  Citrate cycle (TCA cycle)
bxb00220  Arginine biosynthesis
bxb00250  Alanine, aspartate and glutamate metabolism
bxb00260  Glycine, serine and threonine metabolism
bxb00270  Cysteine and methionine metabolism
bxb00310  Lysine degradation
bxb00410  beta-Alanine metabolism
bxb00470  D-Amino acid metabolism
bxb00480  Glutathione metabolism
bxb00630  Glyoxylate and dicarboxylate metabolism
bxb00650  Butanoate metabolism
bxb00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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