KEGG   PATHWAY: bxb00630
Entry
bxb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Paraburkholderia xenovorans LB400
Class
Metabolism; Carbohydrate metabolism
Pathway map
bxb00630  Glyoxylate and dicarboxylate metabolism
bxb00630

Module
bxb_M00012  Glyoxylate cycle [PATH:bxb00630]
bxb_M00621  Glycine cleavage system [PATH:bxb00630]
Other DBs
GO: 0046487 0043648
Organism
Paraburkholderia xenovorans LB400 [GN:bxb]
Gene
DR64_3816  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DR64_3558  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_4024  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DR64_6404  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_452  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_802  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DR64_1272  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_3812  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DR64_4375  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
DR64_5227  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DR64_6452  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DR64_5220  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DR64_2948  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
DR64_3885  DNA binding , excisionase family domain protein [KO:K01647] [EC:2.3.3.1]
DR64_7465  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
DR64_400  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
DR64_5233  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
DR64_6840  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
DR64_6068  thlA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR64_4422  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_40  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_47  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_1932  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_5716  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_446  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_460  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_8102  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_8152  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_7872  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_7534  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_1298  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_46  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DR64_5694  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
DR64_1654  hypothetical protein [KO:K00104] [EC:1.1.99.14]
DR64_4371  glcD; glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
DR64_1655  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
DR64_4372  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
DR64_1656  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
DR64_4373  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
DR64_6530  catalase family protein [KO:K03781] [EC:1.11.1.6]
DR64_1662  katA; catalase [KO:K03781] [EC:1.11.1.6]
DR64_6975  catalase family protein [KO:K03781] [EC:1.11.1.6]
DR64_1159  catalase family protein [KO:K03781] [EC:1.11.1.6]
DR64_1946  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_6797  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_7279  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_7724  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_3218  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR64_4141  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR64_6305  hprA; glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
DR64_3227  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
DR64_2632  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DR64_4806  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DR64_4781  cbbL1; ribulose bisphosphate carboxylase large chain, chromosomal [KO:K01601] [EC:4.1.1.39]
DR64_4780  cbxSC; ribulose bisphosphate carboxylase small chain, chromosomal [KO:K01602] [EC:4.1.1.39]
DR64_5330  aminotransferase class-V family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DR64_6263  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DR64_3682  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
DR64_1590  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
DR64_6888  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
DR64_2233  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DR64_2235  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
DR64_3704  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_5912  lpd3; dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
DR64_492  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_7594  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_2234  gcvH; glycine cleavage system H protein [KO:K02437]
DR64_152  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DR64_7493  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DR64_153  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DR64_154  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DR64_7494  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DR64_1  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
DR64_6793  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR64_6923  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR64_8580  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR64_7723  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR64_2760  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DR64_3125  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
DR64_4879  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DR64_4880  molybdopterin oxidoreductase Fe4S4 domain protein [KO:K00123] [EC:1.17.1.9]
DR64_3126  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DR64_3127  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
DR64_4878  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
DR64_3128  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
DR64_4877  formate dehydrogenase, gamma subunit [KO:K00127]
DR64_7822  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
DR64_2903  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DR64_1788  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR64_6878  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR64_7014  fmdA; formamidase [KO:K01455] [EC:3.5.1.49]
DR64_623  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
DR64_5092  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
DR64_5093  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
DR64_4598  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bxb00010  Glycolysis / Gluconeogenesis
bxb00020  Citrate cycle (TCA cycle)
bxb00030  Pentose phosphate pathway
bxb00053  Ascorbate and aldarate metabolism
bxb00071  Fatty acid degradation
bxb00230  Purine metabolism
bxb00250  Alanine, aspartate and glutamate metabolism
bxb00260  Glycine, serine and threonine metabolism
bxb00620  Pyruvate metabolism
bxb00710  Carbon fixation by Calvin cycle
bxb00750  Vitamin B6 metabolism
bxb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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