KEGG   PATHWAY: cafe00230
Entry
cafe00230                   Pathway                                
Name
Purine metabolism - Corynebacterium afermentans subsp. lipophilum
Class
Metabolism; Nucleotide metabolism
Pathway map
cafe00230  Purine metabolism
cafe00230

Module
cafe_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cafe00230]
cafe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cafe00230]
cafe_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cafe00230]
cafe_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cafe00230]
cafe_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cafe00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium afermentans subsp. lipophilum [GN:cafe]
Gene
CAFEL_00290  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
CAFEL_00880  cyaB; Adenylate cyclase 2 [KO:K01768] [EC:4.6.1.1]
CAFEL_01110  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CAFEL_01845  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
CAFEL_02050  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CAFEL_02055  [KO:K00088] [EC:1.1.1.205]
CAFEL_02065  guaA1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
CAFEL_02445  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CAFEL_02450  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CAFEL_03270  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CAFEL_03275  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CAFEL_03695  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CAFEL_04040  yhcR1; Endonuclease YhcR precursor [KO:K01081] [EC:3.1.3.5]
CAFEL_04380  rihA1; Pyrimidine-specific ribonucleoside hydrolase RihA [KO:K01239] [EC:3.2.2.1]
CAFEL_05815  guaA2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
CAFEL_06075  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
CAFEL_06240  yhcR2; Endonuclease YhcR precursor [KO:K01081] [EC:3.1.3.5]
CAFEL_06245  relA; Bifunctional (p)ppGpp synthase/hydrolase relA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CAFEL_06250  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CAFEL_06310  [KO:K19710] [EC:2.7.7.53]
CAFEL_07390  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CAFEL_07810  nagD; Ribonucleotide monophosphatase NagD [KO:K02566] [EC:3.1.3.5]
CAFEL_07850  rihB; Pyrimidine-specific ribonucleoside hydrolase RihB [KO:K25589]
CAFEL_08020  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CAFEL_08120  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CAFEL_08480  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CAFEL_08810  [KO:K01519] [EC:3.6.1.66]
CAFEL_08865  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
CAFEL_08875  nrdE2; Ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
CAFEL_08955  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CAFEL_09135  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CAFEL_09140  purF; Amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
CAFEL_09155  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269]
CAFEL_09160  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265]
CAFEL_09165  [KO:K23264]
CAFEL_09205  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CAFEL_09215  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CAFEL_09220  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CAFEL_09435  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CAFEL_09705  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
CAFEL_09710  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CAFEL_09885  cysNC; Bifunctional enzyme CysN/CysC [KO:K00956] [EC:2.7.7.4]
CAFEL_09890  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cafe00030  Pentose phosphate pathway
cafe00220  Arginine biosynthesis
cafe00250  Alanine, aspartate and glutamate metabolism
cafe00260  Glycine, serine and threonine metabolism
cafe00340  Histidine metabolism
cafe00630  Glyoxylate and dicarboxylate metabolism
cafe00730  Thiamine metabolism
cafe00740  Riboflavin metabolism
cafe00790  Folate biosynthesis
KO pathway
ko00230   

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