KEGG   PATHWAY: cfir00620
Entry
cfir00620                   Pathway                                
Name
Pyruvate metabolism - Cytobacillus firmus
Class
Metabolism; Carbohydrate metabolism
Pathway map
cfir00620  Pyruvate metabolism
cfir00620

Module
cfir_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:cfir00620]
cfir_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:cfir00620]
Other DBs
GO: 0006090
Organism
Cytobacillus firmus [GN:cfir]
Gene
NAF01_20125  acyl--CoA ligase [KO:K01895] [EC:6.2.1.1]
NAF01_20195  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NAF01_09605  2-oxoacid:acceptor oxidoreductase subunit alpha [KO:K00174] [EC:1.2.7.3 1.2.7.11]
NAF01_09610  2-oxoacid:ferredoxin oxidoreductase subunit beta [KO:K00175] [EC:1.2.7.3 1.2.7.11]
NAF01_08305  pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [KO:K00161] [EC:1.2.4.1]
NAF01_08310  alpha-ketoacid dehydrogenase subunit beta [KO:K00162] [EC:1.2.4.1]
NAF01_08315  2-oxo acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
NAF01_23185  2-oxo acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
NAF01_08320  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NAF01_10830  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NAF01_18200  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NAF01_23180  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NAF01_11645  pflB; formate C-acetyltransferase [KO:K00656] [EC:2.3.1.54]
NAF01_12685  acetaldehyde dehydrogenase (acetylating) [KO:K00132] [EC:1.2.1.10]
NAF01_04855  glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
NAF01_11345  glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
NAF01_14180  glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
NAF01_03460  NAD(P)-dependent alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
NAF01_20075  acetate kinase [KO:K00925] [EC:2.7.2.1]
NAF01_24130  pta; phosphate acetyltransferase [KO:K00625] [EC:2.3.1.8]
NAF01_12675  phosphate propanoyltransferase [KO:K15024] [EC:2.3.1.8]
NAF01_19955  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
NAF01_19965  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
NAF01_18300  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
NAF01_08635  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K02160]
NAF01_08630  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
NAF01_18295  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
NAF01_19970  accD; acetyl-CoA carboxylase, carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
NAF01_11550  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
NAF01_12425  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
NAF01_21970  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
NAF01_04545  acetyl-CoA hydrolase/transferase family protein [KO:K18118] [EC:2.8.3.18]
NAF01_23120  CoA-binding protein [KO:K24012] [EC:6.2.1.13]
NAF01_18560  L-lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
NAF01_24535  L-lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
NAF01_02250  alpha-hydroxy-acid oxidizing protein [KO:K00467] [EC:1.13.12.4]
NAF01_09930  FAD-binding protein [KO:K00102] [EC:1.1.2.4]
NAF01_02485  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
NAF01_06165  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
NAF01_11810  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
NAF01_01280  glyoxalase/bleomycin resistance/dioxygenase family protein [KO:K01759] [EC:4.4.1.5]
NAF01_02725  VOC family protein [KO:K01759] [EC:4.4.1.5]
NAF01_05445  VOC family protein [KO:K01759] [EC:4.4.1.5]
NAF01_13555  VOC family protein [KO:K01759] [EC:4.4.1.5]
NAF01_18505  MBL fold metallo-hydrolase [KO:K01069] [EC:3.1.2.6]
NAF01_12575  larA; nickel-dependent lactate racemase [KO:K22373] [EC:5.1.2.1]
NAF01_10180  NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
NAF01_19980  NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
NAF01_08450  pyc; pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
NAF01_12655  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NAF01_19925  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NAF01_24490  malate:quinone oxidoreductase [KO:K00116] [EC:1.1.5.4]
NAF01_05395  fumarate hydratase [KO:K01676] [EC:4.2.1.2]
NAF01_06450  fumC; class II fumarate hydratase [KO:K01679] [EC:4.2.1.2]
NAF01_20505  pckA; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
NAF01_15995  malate synthase G [KO:K01638] [EC:2.3.3.9]
NAF01_06870  thiolase family protein [KO:K00626] [EC:2.3.1.9]
NAF01_13240  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NAF01_23080  thiolase family protein [KO:K00626] [EC:2.3.1.9]
NAF01_24030  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NAF01_18015  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NAF01_19620  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
cfir00010  Glycolysis / Gluconeogenesis
cfir00020  Citrate cycle (TCA cycle)
cfir00061  Fatty acid biosynthesis
cfir00250  Alanine, aspartate and glutamate metabolism
cfir00260  Glycine, serine and threonine metabolism
cfir00290  Valine, leucine and isoleucine biosynthesis
cfir00300  Lysine biosynthesis
cfir00630  Glyoxylate and dicarboxylate metabolism
cfir00640  Propanoate metabolism
cfir00650  Butanoate metabolism
cfir00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   
LinkDB

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