KEGG   PATHWAY: cpea00564
Entry
cpea00564                   Pathway                                
Name
Glycerophospholipid metabolism - Chaetura pelagica (chimney swift)
Class
Metabolism; Lipid metabolism
Pathway map
cpea00564  Glycerophospholipid metabolism
cpea00564

Module
cpea_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:cpea00564]
cpea_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cpea00564]
cpea_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cpea00564]
Other DBs
GO: 0006650
Organism
Chaetura pelagica (chimney swift) [GN:cpea]
Gene
104384840  PPAPDC1B; LOW QUALITY PROTEIN: phosphatidate phosphatase PPAPDC1B [KO:K18693] [EC:3.6.1.75 3.1.3.4]
104384849  AGPAT6; glycerol-3-phosphate acyltransferase 6 [KO:K13506] [EC:2.3.1.15]
104385033  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
104385037  CRLS1; cardiolipin synthase [KO:K08744] [EC:2.7.8.41]
104385106  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
104385187  PPAP2B; lipid phosphate phosphohydrolase 3 [KO:K01080] [EC:3.1.3.4]
104385595  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
104385628  CEPT1; choline/ethanolaminephosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
104385808  PNPLA7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
104386065  PNPLA6; LOW QUALITY PROTEIN: neuropathy target esterase [KO:K14676] [EC:3.1.1.5]
104386169  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
104386345  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
104386643  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
104387071  [KO:K01047] [EC:3.1.1.4]
104387073  [KO:K01047] [EC:3.1.1.4]
104387108  [KO:K01047] [EC:3.1.1.4]
104387149  PLD4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
104387442  [KO:K00006] [EC:1.1.1.8]
104387626  PLA2G12B; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
104387662  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
104387712  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
104387922  [KO:K00901] [EC:2.7.1.107]
104388587  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
104388912  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
104388977  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
104389252  PLA1A; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
104389295  [KO:K01047] [EC:3.1.1.4]
104389492  PCYT1B; choline-phosphate cytidylyltransferase B [KO:K00968] [EC:2.7.7.15]
104389758  LPIN3; phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
104389835  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
104389900  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
104390143  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
104390166  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
104390230  [KO:K13509] [EC:2.3.1.51]
104390361  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
104390438  [KO:K16342] [EC:3.1.1.4]
104390440  [KO:K16342] [EC:3.1.1.4]
104390457  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
104390477  [KO:K16342] [EC:3.1.1.4]
104390480  [KO:K16342] [EC:3.1.1.4]
104390481  [KO:K16342] [EC:3.1.1.4]
104390482  [KO:K16342] [EC:3.1.1.4]
104390483  [KO:K16342] [EC:3.1.1.4]
104390485  [KO:K16342] [EC:3.1.1.4]
104390486  PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
104390627  PCYT1A; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
104390791  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
104391005  [KO:K13509] [EC:2.3.1.51]
104391096  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
104391318  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
104391452  SAMD8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:3.1.4.62]
104391536  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
104391744  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
104391794  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
104392095  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
104392319  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
104392435  PPAP2C; lipid phosphate phosphohydrolase 2 [KO:K01080] [EC:3.1.3.4]
104392739  EPT1; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
104393196  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
104393208  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
104393456  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
104393693  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104393820  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
104393931  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
104394027  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
104394360  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
104394407  PPAPDC1A; phosphatidate phosphatase PPAPDC1A [KO:K18693] [EC:3.6.1.75 3.1.3.4]
104394490  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
104394493  SGMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
104394506  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104394616  GNPAT; LOW QUALITY PROTEIN: dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
104394803  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
104394876  MBOAT1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
104395137  PISD; phosphatidylserine decarboxylase proenzyme isoform X1 [KO:K01613] [EC:4.1.1.65]
104395152  PLA2G1B; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104395668  PPAP2A; lipid phosphate phosphohydrolase 1 [KO:K01080] [EC:3.1.3.4]
104396086  CHPT1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
104396654  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
104396708  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
104396899  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
104396912  [KO:K00993] [EC:2.7.8.1]
104396940  LPIN2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
104397529  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
104397756  SGMS1; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
104397836  LCAT; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
104397899  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
104398153  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
104398218  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104398252  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
104398518  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
104398551  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
104398795  [KO:K13506] [EC:2.3.1.15]
104398797  [KO:K13506] [EC:2.3.1.15]
104398854  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cpea00010  Glycolysis / Gluconeogenesis
cpea00260  Glycine, serine and threonine metabolism
cpea00561  Glycerolipid metabolism
cpea00562  Inositol phosphate metabolism
cpea00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cpea00565  Ether lipid metabolism
cpea00620  Pyruvate metabolism
KO pathway
ko00564   

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