KEGG   PATHWAY: cpla00564
Entry
cpla00564                   Pathway                                
Name
Glycerophospholipid metabolism - Chiloscyllium plagiosum (whitespotted bambooshark)
Class
Metabolism; Lipid metabolism
Pathway map
cpla00564  Glycerophospholipid metabolism
cpla00564

Module
cpla_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:cpla00564]
cpla_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cpla00564]
cpla_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cpla00564]
Other DBs
GO: 0006650
Organism
Chiloscyllium plagiosum (whitespotted bambooshark) [GN:cpla]
Gene
122549960  glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
122551672  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
122543291  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like isoform X1 [KO:K00006] [EC:1.1.1.8]
122551609  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
122561244  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
122543105  glycerol-3-phosphate acyltransferase 1, mitochondrial-like isoform X1 [KO:K00629] [EC:2.3.1.15]
122539444  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
122543164  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
122564635  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
122555437  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
122552976  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
122541960  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
122563613  lysophospholipid acyltransferase 2-like isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
122564375  mboat1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
122541510  lysophospholipid acyltransferase 2-like isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
122542789  gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
122562028  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
122562029  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
122554305  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
122549242  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
122565378  phospholipid phosphatase 2-like [KO:K01080] [EC:3.1.3.4]
122552203  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
122548596  phosphatidate phosphatase LPIN1-like [KO:K15728] [EC:3.1.3.4]
122549467  lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
122559963  phosphatidate phosphatase LPIN2-like [KO:K15728] [EC:3.1.3.4]
122561181  plpp4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
122543031  phospholipid phosphatase 4-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
122555774  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
122562366  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
122539562  diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
122549795  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
122557073  si:dkey-172j4.3; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
122551298  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
122551880  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
122559469  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
122559338  cholinephosphotransferase 1-like isoform X1 [KO:K00994] [EC:2.7.8.2]
122563337  choline/ethanolaminephosphotransferase 1-like [KO:K13644] [EC:2.7.8.1 2.7.8.2]
122544415  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
122556122  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
122543821  pld7; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
122553572  5'-3' exonuclease PLD3-like isoform X1 [KO:K16860] [EC:3.1.4.4]
122542714  pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
122558505  lcat; phosphatidylcholine-sterol acyltransferase isoform X1 [KO:K00650] [EC:2.3.1.43]
122560478  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
122548778  basic phospholipase A2 nigroxin A-like [KO:K01047] [EC:3.1.1.4]
122562419  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
122562488  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
122562836  phospholipase A2, minor isoenzyme-like isoform X1 [KO:K01047] [EC:3.1.1.4]
122564031  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
122558063  basic phospholipase A2 F17-like [KO:K01047] [EC:3.1.1.4]
122541712  basic phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
122541910  pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
122542977  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
122553857  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
122554454  cytosolic phospholipase A2-like isoform X1 [KO:K16342] [EC:3.1.1.4]
122542241  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
122553958  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
122548494  plb1; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
122545609  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
122548189  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
122549735  lysophosphatidylcholine acyltransferase 1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
122558437  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
122549099  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
122558503  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
122563689  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
122564745  pnpla7b; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
122552155  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
122553075  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
122541875  chata; choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]
122544299  ache; acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
122561775  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
122557832  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
122539968  phosphoethanolamine/phosphocholine phosphatase-like [KO:K06124] [EC:3.1.3.75]
122555086  choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
122556129  choline-phosphate cytidylyltransferase A-like [KO:K00968] [EC:2.7.7.15]
122540463  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
122561582  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
122563064  ethanolamine kinase 1-like [KO:K00894] [EC:2.7.1.82]
122557782  ethanolamine kinase 1-like isoform X1 [KO:K00894] [EC:2.7.1.82]
122562244  pcyt2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
122552249  ethanolamine-phosphate phospho-lyase-like isoform X1 [KO:K14286] [EC:4.2.3.2]
122560419  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
122555049  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
122543050  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
122555234  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
122548971  phosphatidylserine synthase 1-like [KO:K08729] [EC:2.7.8.-]
122557940  ptdss2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
122562846  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
122562217  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
122553079  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
122552849  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
122546693  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cpla00010  Glycolysis / Gluconeogenesis
cpla00260  Glycine, serine and threonine metabolism
cpla00561  Glycerolipid metabolism
cpla00562  Inositol phosphate metabolism
cpla00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cpla00565  Ether lipid metabolism
cpla00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

DBGET integrated database retrieval system