KEGG   PATHWAY: cpoo00564
Entry
cpoo00564                   Pathway                                
Name
Glycerophospholipid metabolism - Crocodylus porosus (Australian saltwater crocodile)
Class
Metabolism; Lipid metabolism
Pathway map
cpoo00564  Glycerophospholipid metabolism
cpoo00564

Module
cpoo_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:cpoo00564]
cpoo_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cpoo00564]
Other DBs
GO: 0006650
Organism
Crocodylus porosus (Australian saltwater crocodile) [GN:cpoo]
Gene
109305877  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
109305959  PCYT1B; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
109306477  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
109307014  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
109307217  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
109307912  PLPP1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
109308438  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
109308537  PCYT1A; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
109308679  [KO:K00901] [EC:2.7.1.107]
109309339  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
109309394  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
109309396  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
109309403  SGMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109310385  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
109310504  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109310773  [KO:K01047] [EC:3.1.1.4]
109310948  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
109311086  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
109311568  SELENOI; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
109311642  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
109311663  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109311720  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
109312508  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
109312529  SGMS1; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109312854  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
109312880  PLA2G1B; phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
109313184  LPIN3; phosphatidate phosphatase LPIN3 isoform X1 [KO:K15728] [EC:3.1.3.4]
109313546  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
109313643  LPCAT1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109313801  PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
109314010  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
109314367  [KO:K01047] [EC:3.1.1.4]
109314368  [KO:K01047] [EC:3.1.1.4]
109314369  [KO:K01047] [EC:3.1.1.4]
109314419  [KO:K01047] [EC:3.1.1.4]
109314671  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
109314886  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
109315000  DGKE; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
109315279  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
109315933  CHPT1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
109315942  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
109316004  MBOAT1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109316012  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109316397  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
109316516  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
109317298  PLPP5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
109317336  CDS2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
109317399  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
109317594  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
109317650  [KO:K13509] [EC:2.3.1.51]
109317754  ETNK2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
109317762  LPIN2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
109318177  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
109318194  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
109318382  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
109318472  [KO:K00993] [EC:2.7.8.1]
109318715  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
109318926  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
109319037  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
109319076  PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
109319217  PLA1A; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
109319321  [KO:K01047] [EC:3.1.1.4]
109319375  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
109319474  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
109319703  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
109319799  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
109320008  GNPAT; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
109320061  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
109320472  PLPP2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
109320622  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
109320631  PLD4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
109320783  [KO:K16342] [EC:3.1.1.4]
109320784  [KO:K16342] [EC:3.1.1.4]
109320785  [KO:K16342] [EC:3.1.1.4]
109320786  [KO:K16342] [EC:3.1.1.4]
109320957  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
109321068  [KO:K16342] [EC:3.1.1.4]
109321069  [KO:K16342] [EC:3.1.1.4]
109321579  [KO:K16342] [EC:3.1.1.4]
109321613  PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
109321619  [KO:K16342] [EC:3.1.1.4]
109321622  [KO:K16342] [EC:3.1.1.4]
109321647  [KO:K16342] [EC:3.1.1.4]
109321872  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
109322272  GPAT3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
109322895  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
109323018  [KO:K00006] [EC:1.1.1.8]
109323569  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
109324112  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
109324173  SAMD8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:2.7.8.48 3.1.4.62]
109324290  PLPP4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
109324367  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
109324424  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cpoo00010  Glycolysis / Gluconeogenesis
cpoo00260  Glycine, serine and threonine metabolism
cpoo00561  Glycerolipid metabolism
cpoo00562  Inositol phosphate metabolism
cpoo00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cpoo00565  Ether lipid metabolism
cpoo00620  Pyruvate metabolism
KO pathway
ko00564   

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