KEGG   PATHWAY: csyr00330
Entry
csyr00330                   Pathway                                
Name
Arginine and proline metabolism - Carlito syrichta (Philippine tarsier)
Class
Metabolism; Amino acid metabolism
Pathway map
csyr00330  Arginine and proline metabolism
csyr00330

Module
csyr_M00015  Proline biosynthesis, glutamate => proline [PATH:csyr00330]
csyr_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:csyr00330]
csyr_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:csyr00330]
csyr_M00970  Proline degradation, proline => glutamate [PATH:csyr00330]
csyr_M00972  Proline metabolism [PATH:csyr00330]
Other DBs
GO: 0006525 0006560
Organism
Carlito syrichta (Philippine tarsier) [GN:csyr]
Gene
103249599  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
103249678  PRODH2; LOW QUALITY PROTEIN: hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
103250172  [KO:K13240] [EC:1.14.13.39]
103251656  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
103251820  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103251904  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
103252234  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
103252743  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
103253648  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
103254300  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
103256085  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
103256090  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
103256156  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103256787  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103256876  OAT; ornithine aminotransferase, mitochondrial isoform X3 [KO:K00819] [EC:2.6.1.13]
103256885  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
103259046  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
103259491  CKM; creatine kinase M-type [KO:K27382]
103260477  AGMAT; agmatinase, mitochondrial [KO:K27001]
103262015  [KO:K00933] [EC:2.7.3.2]
103262092  [KO:K00318] [EC:1.5.5.2]
103262447  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
103262584  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
103262771  PYCR1; LOW QUALITY PROTEIN: pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
103264635  SAT2; diamine acetyltransferase 2 isoform X1 [KO:K00657] [EC:2.3.1.57]
103264836  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
103264894  ALDH3A2; fatty aldehyde dehydrogenase isoform X1 [KO:K00128] [EC:1.2.1.3]
103264960  GATM; glycine amidinotransferase, mitochondrial isoform X1 [KO:K00613] [EC:2.1.4.1]
103264989  [KO:K01611] [EC:4.1.1.50]
103266646  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
103267975  ODC1; ornithine decarboxylase isoform X1 [KO:K01581] [EC:4.1.1.17]
103268064  SAT1; diamine acetyltransferase 1 isoform X2 [KO:K00657] [EC:2.3.1.57]
103268643  [KO:K00802] [EC:2.5.1.22]
103269196  [KO:K01581] [EC:4.1.1.17]
103269950  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
103270543  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
103271557  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
103271722  GOT2; aspartate aminotransferase, mitochondrial isoform X1 [KO:K14455] [EC:2.6.1.1]
103271899  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
103272785  [KO:K00128] [EC:1.2.1.3]
103273649  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103274370  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
103274448  ARG1; arginase-1 isoform X1 [KO:K01476] [EC:3.5.3.1]
103274598  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103274863  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
103274954  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
103275280  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
103276517  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
103276518  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
csyr00020  Citrate cycle (TCA cycle)
csyr00220  Arginine biosynthesis
csyr00250  Alanine, aspartate and glutamate metabolism
csyr00260  Glycine, serine and threonine metabolism
csyr00270  Cysteine and methionine metabolism
csyr00310  Lysine degradation
csyr00410  beta-Alanine metabolism
csyr00470  D-Amino acid metabolism
csyr00480  Glutathione metabolism
csyr00630  Glyoxylate and dicarboxylate metabolism
csyr00650  Butanoate metabolism
csyr00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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