KEGG   PATHWAY: dme00562
Entry
dme00562                    Pathway                                
Name
Inositol phosphate metabolism - Drosophila melanogaster (fruit fly)
Class
Metabolism; Carbohydrate metabolism
Pathway map
dme00562  Inositol phosphate metabolism
dme00562

Module
dme_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:dme00562]
dme_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:dme00562]
Other DBs
GO: 0006020
Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG10260  Pi4KIIIalpha; phosphatidylinositol 4-kinase III alpha, isoform D [KO:K00888] [EC:2.7.1.67]
Dmel_CG10426  INPP5E; inositol polyphosphate 5-phosphatase E, isoform B [KO:K20278] [EC:3.1.3.36]
Dmel_CG11143  Inos; myo-inositol-1-phosphate synthase [KO:K01858] [EC:5.5.1.4]
Dmel_CG11621  Pi3K68D; phosphatidylinositol 3-kinase 68D, isoform D [KO:K00923] [EC:2.7.1.154]
Dmel_CG13688  Ipk2; inositol phosphate kinase 2 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
Dmel_CG17026  CG17026; uncharacterized protein [KO:K01092] [EC:3.1.3.25]
Dmel_CG17027  CG17027; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17028  CG17028; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17029  CG17029; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17471  PIP4K; phosphatidylinositol 5-phosphate 4-kinase, isoform B [KO:K00889] [EC:2.7.1.68]
Dmel_CG17840  FIG4; FIG4 phosphoinositide 5-phosphatase [KO:K22913] [EC:3.1.3.-]
Dmel_CG17896  CG17896; uncharacterized protein, isoform B [KO:K00140] [EC:1.2.1.18 1.2.1.27]
Dmel_CG2171  Tpi; triose phosphate isomerase, isoform B [KO:K01803] [EC:5.3.1.1]
Dmel_CG2929  Pi4KIIalpha; phosphatidylinositol 4-kinase II alpha, isoform E [KO:K13711] [EC:2.7.1.67]
Dmel_CG3028  Ipp; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
Dmel_CG30295  Ipk1; inositol phosphate kinase 1, isoform A [KO:K10572] [EC:2.7.1.158]
Dmel_CG3530  Mtmr6; myotubularin related protein 6, isoform C [KO:K18083] [EC:3.1.3.64 3.1.3.95]
Dmel_CG3573  Ocrl; oculocerebrorenal syndrome of lowe, isoform B [KO:K01099] [EC:3.1.3.36]
Dmel_CG3620  norpA; no receptor potential A, isoform D [KO:K05858] [EC:3.1.4.11]
Dmel_CG3632  CG3632; uncharacterized protein, isoform E [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
Dmel_CG3682  PIP5K59B; phosphatidylinositol 4-phosphate 5-kinase 59B, isoform I [KO:K00889] [EC:2.7.1.68]
Dmel_CG4026  IP3K1; inositol 1,4,5-triphosphate kinase 1, isoform B [KO:K00911] [EC:2.7.1.127]
Dmel_CG4123  Mipp1; multiple inositol polyphosphate phosphatase 1, isoform C [KO:K03103] [EC:3.1.3.62 3.1.3.80]
Dmel_CG4141  Pi3K92E; phosphatidylinositol 3-kinase 92E, isoform C [KO:K00922] [EC:2.7.1.153]
Dmel_CG4200  sl; small wing [KO:K01116] [EC:3.1.4.11]
Dmel_CG42271  CG42271; uncharacterized protein, isoform C [KO:K01109] [EC:3.1.3.66]
Dmel_CG42283  5PtaseI; inositol polyphosphate-5-phosphatase type I, isoform C [KO:K01106] [EC:3.1.3.56]
Dmel_CG4317  Mipp2; multiple inositol polyphosphate phosphatase 2 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
Dmel_CG45017  IP3K2; inositol 1,4,5-triphosphate kinase 2, isoform C [KO:K00911] [EC:2.7.1.127]
Dmel_CG4574  Plc21C; phospholipase C at 21C, isoform D [KO:K05858] [EC:3.1.4.11]
Dmel_CG5373  Pi3K59F; phosphatidylinositol 3-kinase 59F [KO:K00914] [EC:2.7.1.137]
Dmel_CG5671  Pten; phosphatase and tensin homolog, isoform G [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Dmel_CG6355  fab1; fab1 kinase, isoform A [KO:K00921] [EC:2.7.1.150]
Dmel_CG6542  EDTP; Egg-derived tyrosine phosphatase, isoform A [KO:K18086] [EC:3.1.3.64 3.1.3.95]
Dmel_CG6562  Synj; synaptojanin, isoform C [KO:K20279] [EC:3.1.3.36]
Dmel_CG6910  Miox; Myo-inositol oxygenase, isoform C [KO:K00469] [EC:1.13.99.1]
Dmel_CG7004  fwd; four wheel drive, isoform D [KO:K19801] [EC:2.7.1.67]
Dmel_CG7956  sp3; spermathreecae, isoform G [KO:K21798] [EC:3.1.3.-]
Dmel_CG9115  mtm; myotubularin, isoform B [KO:K18081] [EC:3.1.3.64 3.1.3.95]
Dmel_CG9128  Sac1; Sac1 phosphatase, isoform B [KO:K21797] [EC:3.1.3.-]
Dmel_CG9245  Pis; phosphatidylinositol synthase, isoform A [KO:K00999] [EC:2.7.8.11]
Dmel_CG9389  CG9389; uncharacterized protein [KO:K01092] [EC:3.1.3.25]
Dmel_CG9391  CG9391; uncharacterized protein, isoform A [KO:K01092] [EC:3.1.3.25]
Dmel_CG9784  CG9784; uncharacterized protein, isoform C [KO:K24222]
Dmel_CG9985  sktl; skittles, isoform B [KO:K00889] [EC:2.7.1.68]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
dme00010  Glycolysis / Gluconeogenesis
dme00020  Citrate cycle (TCA cycle)
dme00040  Pentose and glucuronate interconversions
dme00564  Glycerophospholipid metabolism
KO pathway
ko00562   

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