KEGG   PATHWAY: dme03083
Entry
dme03083                    Pathway                                
Name
Polycomb repressive complex - Drosophila melanogaster (fruit fly)
Class
Genetic Information Processing; Chromosome
Pathway map
dme03083  Polycomb repressive complex
dme03083

Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG10392  sxc; super sex combs, isoform B [KO:K09667] [EC:2.4.1.255]
Dmel_CG10862  CG10862; uncharacterized protein [KO:K06689] [EC:2.3.2.23]
Dmel_CG10931  CG10931; uncharacterized protein [KO:K14963]
Dmel_CG11033  Kdm2; lysine demethylase 2, isoform C [KO:K10276] [EC:1.14.11.27]
Dmel_CG11799  FoxK; forkhead box K, isoform N [KO:K09404]
Dmel_CG11941  SkpC; SKP1-related C [KO:K03094]
Dmel_CG11942  SkpE; SKP1-related E [KO:K03094]
Dmel_CG12190  RYBP; ring and YY1 binding protein, isoform B [KO:K11468]
Dmel_CG12227  SkpF; SKP1-related F [KO:K03094]
Dmel_CG12700  SkpD; SKP1-related D [KO:K03094]
Dmel_CG13591  Ssl; suppressor of Stellate-like [KO:K03115]
Dmel_CG13598  sba; six-banded, isoform C [KO:K23219]
Dmel_CG14614  wap; wings apart, isoform C [KO:K11805]
Dmel_CG1490  Usp7; Ubiquitin-specific protease 7, isoform B [KO:K11838] [EC:3.4.19.12]
Dmel_CG14941  esc; extra sexcombs [KO:K11462]
Dmel_CG15224  CkIIbeta; casein kinase II beta subunit, isoform E [KO:K03115]
Dmel_CG15319  nej; nejire, isoform C [KO:K04498] [EC:2.3.1.48]
Dmel_CG1575  CG1575; uncharacterized protein, isoform B [KO:K14827]
Dmel_CG15800  CG15800; uncharacterized protein [KO:K03094]
Dmel_CG16975  Sfmbt; Scm-related gene containing four mbt domains, isoform D [KO:K26269]
Dmel_CG16983  SkpA; SKP1-related A, isoform H [KO:K03094]
Dmel_CG1710  Hcf; host cell factor, isoform A [KO:K14966]
Dmel_CG17437  wds; will die slowly, isoform B [KO:K14963]
Dmel_CG17743  pho; pleiohomeotic, isoform A [KO:K09201]
Dmel_CG18412  ph-p; polyhomeotic proximal, isoform A [KO:K11456]
Dmel_CG32616  Ste12DOR; stellate 12D orphon [KO:K03115]
Dmel_CG33236  [KO:K03115]
Dmel_CG33237  [KO:K03115]
Dmel_CG33238  [KO:K03115]
Dmel_CG33239  [KO:K03115]
Dmel_CG33240  [KO:K03115]
Dmel_CG33241  [KO:K03115]
Dmel_CG33242  [KO:K03115]
Dmel_CG33243  [KO:K03115]
Dmel_CG33244  [KO:K03115]
Dmel_CG33245  [KO:K03115]
Dmel_CG33246  [KO:K03115]
Dmel_CG33247  [KO:K03115]
Dmel_CG3445  phol; pleiohomeotic like, isoform B [KO:K09201]
Dmel_CG3654  Jarid2; Jumonji, AT rich interactive domain 2 [KO:K11478]
Dmel_CG3886  Psc; posterior sex combs, isoform B [KO:K11459]
Dmel_CG3895  ph-d; polyhomeotic distal, isoform B [KO:K11456]
Dmel_CG40635  CG40635; uncharacterized protein [KO:K03115]
Dmel_CG4165  Usp16-45; ubiquitin specific protease 16/45, isoform F [KO:K11844] [EC:3.4.19.12]
Dmel_CG4195  l(3)73Ah; lethal (3) 73Ah, isoform B [KO:K11488]
Dmel_CG4236  Caf1-55; chromatin assembly factor 1, p55 subunit, isoform A [KO:K10752]
Dmel_CG42398  [KO:K03115]
Dmel_CG43089  CG43089; uncharacterized protein, isoform B [KO:K03094]
Dmel_CG4654  Dp; DP transcription factor, isoform A [KO:K04683]
Dmel_CG5109  Pcl; polycomblike, isoform B [KO:K11485]
Dmel_CG5202  escl; escl, isoform C [KO:K11462]
Dmel_CG5595  Sce; Sex combs extra [KO:K10695] [EC:2.3.2.27]
Dmel_CG5954  l(3)mbt; lethal (3) malignant brain tumor [KO:K24387]
Dmel_CG6502  E(z); enhancer of zeste, isoform B [KO:K11430] [EC:2.1.1.356]
Dmel_CG6620  aurB; aurora B [KO:K11479] [EC:2.7.11.1]
Dmel_CG6990  HP1c; heterochromatin protein 1c [KO:K11586]
Dmel_CG7425  eff; effete, isoform B [KO:K06689] [EC:2.3.2.23]
Dmel_CG7471  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
Dmel_CG8013  Su(z)12; Su(z)12, isoform B [KO:K11463]
Dmel_CG8445  caly; calypso, isoform A [KO:K08588] [EC:3.4.19.12]
Dmel_CG8787  Asx; additional sex combs, isoform A [KO:K11471]
Dmel_CG8881  SkpB; SKP1-related B [KO:K03094]
Dmel_CG8914  CkIIbeta2; casein kinase II beta2 subunit [KO:K03115]
Dmel_CG9397  jing; jing, isoform H [KO:K17452]
Dmel_CG9495  Scm; Sex comb on midleg, isoform B [KO:K11461]
Dmel_CG9648  Max; Max, isoform C [KO:K04453]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 143:511-527 (2024)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   

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