KEGG   PATHWAY: ecj00620
Entry
ecj00620                    Pathway                                
Name
Pyruvate metabolism - Escherichia coli K-12 W3110
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecj00620  Pyruvate metabolism
ecj00620

Module
ecj_M00168  CAM (Crassulacean acid metabolism), dark [PATH:ecj00620]
ecj_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ecj00620]
ecj_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ecj00620]
Other DBs
GO: 0006090
Organism
Escherichia coli K-12 W3110 [GN:ecj]
Gene
JW0073  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
JW0110  aceE; pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding [KO:K00163] [EC:1.2.4.1]
JW0111  aceF; pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2 [KO:K00627] [EC:2.3.1.12]
JW0112  lpd; lipoamide dehydrogenase, E3 component is part of three enzyme complexes [KO:K00382] [EC:1.8.1.4]
JW0180  accA; acetylCoA carboxylase, carboxytransferase, alpha subunit [KO:K01962] [EC:6.4.1.2 2.1.3.15]
JW0202  gloB; predicted hydroxyacylglutathione hydrolase [KO:K01069] [EC:3.1.2.6]
JW0317  yahK; predicted oxidoreductase, Zn-dependent and NAD(P)-binding [KO:K13979] [EC:1.1.1.2]
JW0342  mhpF; acetaldehyde-CoA dehydrogenase II, NAD-binding [KO:K04073] [EC:1.2.1.10]
JW0347  frmA; alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
JW0855  poxB; pyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding [KO:K00156] [EC:1.2.5.1]
JW0886  pflB; pyruvate formate lyase I [KO:K00656] [EC:2.3.1.54]
JW0910  ycbL; predicted metal-binding enzyme [KO:K01069] [EC:3.1.2.6]
JW1228  adhE; fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenase and pyruvate-formate lyase deactivase [KO:K04072] [EC:1.2.1.10 1.1.1.1]
JW1372  ydbK; fused predicted Fe-S subunit of pyruvate-flavodoxin oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.7.-]
JW1375  ldhA; fermentative D-lactate dehydrogenase, NAD-dependent [KO:K03778] [EC:1.1.1.28]
JW1412  aldA; aldehyde dehydrogenase A, NAD-linked [KO:K07248] [EC:1.2.1.22 1.2.1.21]
JW1474  adhP; alcohol dehydrogenase, 1-propanol preferring [KO:K13953] [EC:1.1.1.1]
JW1603  fumC; fumarate hydratase (fumarase C), aerobic Class II [KO:K01679] [EC:4.2.1.2]
JW1604  fumA; aerobic Class I fumarate hydratase [KO:K01676] [EC:4.2.1.2]
JW1643  gloA; glyoxalase I, Ni-dependent [KO:K01759] [EC:4.4.1.5]
JW1665  ydhZ; hypothetical protein [KO:K01675]
JW1666  pykF; pyruvate kinase I [KO:K00873] [EC:2.7.1.40]
JW1692  pps; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
JW1843  pykA; pyruvate kinase II [KO:K00873] [EC:2.7.1.40]
JW1950  hchA; Hsp31 molecular chaperone [KO:K05523] [EC:4.2.1.130 3.5.1.124]
JW2121  dld; D-lactate dehydrogenase, FAD-binding, NADH independent [KO:K03777] [EC:1.1.5.12]
JW2198  mqo; malate dehydrogenase, FAD/NAD(P)-binding domain [KO:K00116] [EC:1.1.5.4]
JW2218  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
JW2293  ackA; acetate kinase A and propionate kinase 2 [KO:K00925] [EC:2.7.2.1]
JW2294  pta; phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
JW2313  accD; acetylCoA carboxylase, beta (carboxyltranferase) subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
JW2437  eutG; predicted alcohol dehydrogenase in ethanolamine utilization [KO:K04022]
JW2439  eutE; predicted aldehyde dehydrogenase, ethanolamine utilization protein [KO:K04021]
JW2442  eutI; predicted phosphotransacetylase subunit [KO:K04020]
JW2447  maeB; fused malic enzyme predicted oxidoreductase and predicted phosphotransacetylase [KO:K00029] [EC:1.1.1.40]
JW2896  yggD; predicted DNA-binding transcriptional regulator [KO:K01774]
JW2943  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
JW3205  mdh; malate dehydrogenase, NAD(P)-binding [KO:K00024] [EC:1.1.1.37]
JW3223  accB; acetyl CoA carboxylase, BCCP subunit [KO:K02160]
JW3224  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
JW3366  pck; phosphoenolpyruvate carboxykinase [KO:K01610] [EC:4.1.1.49]
JW3561  aldB; aldehyde dehydrogenase B [KO:K00138] [EC:1.2.1.-]
JW3580  lldD; L-lactate dehydrogenase, FMN-linked [KO:K00101] [EC:1.1.2.3]
JW3928  ppc; phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
JW3974  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
JW4030  acs; bifunctional acetyl-CoA synthetase and propionyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
JW4083  fumB; anaerobic class I fumarate hydratase [KO:K01676] [EC:4.2.1.2]
JW4112  frdD; fumarate reductase (anaerobic), membrane anchor subunit [KO:K00247]
JW4113  frdC; fumarate reductase (anaerobic), membrane anchor subunit [KO:K00246]
JW4114  frdB; fumarate reductase (anaerobic), Fe-S subunit [KO:K00245] [EC:1.3.5.1]
JW4115  frdA; fumarate reductase (anaerobic) catalytic and NAD/flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
JW5131  yccX; predicted acylphosphatase [KO:K01512] [EC:3.6.1.7]
JW5146  ycdW; 2-ketoacid reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
JW5238  sfcA; malate dehydrogenase, NAD-requiring [KO:K00027] [EC:1.1.1.38]
JW5453  yqeF; predicted acyltransferase [KO:K00626] [EC:2.3.1.9]
JW5522  tdcE; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase [KO:K00656] [EC:2.3.1.54]
JW5648  yiaY; predicted Fe-containing alcohol dehydrogenase [KO:K13954] [EC:1.1.1.1]
JW5656  tiaE; 2-keto-D-gluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
JW5761  yjgB; predicted alcohol dehydrogenase, Zn-dependent and NAD(P)-binding [KO:K12957] [EC:1.1.1.2 1.1.1.183]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
ecj00010  Glycolysis / Gluconeogenesis
ecj00020  Citrate cycle (TCA cycle)
ecj00061  Fatty acid biosynthesis
ecj00250  Alanine, aspartate and glutamate metabolism
ecj00260  Glycine, serine and threonine metabolism
ecj00290  Valine, leucine and isoleucine biosynthesis
ecj00300  Lysine biosynthesis
ecj00630  Glyoxylate and dicarboxylate metabolism
ecj00640  Propanoate metabolism
ecj00650  Butanoate metabolism
ecj00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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