KEGG   PATHWAY: ecj00250
Entry
ecj00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Escherichia coli K-12 W3110
Class
Metabolism; Amino acid metabolism
Pathway map
ecj00250  Alanine, aspartate and glutamate metabolism
ecj00250

Module
ecj_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:ecj00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Escherichia coli K-12 W3110 [GN:ecj]
Gene
JW0030  carA; carbamoyl phosphate synthetase small subunit, glutamine amidotransferase [KO:K01956] [EC:6.3.5.5]
JW0031  carB; carbamoyl-phosphate synthase large subunit [KO:K01955] [EC:6.3.5.5]
JW0474  ybaS; predicted glutaminase [KO:K01425] [EC:3.5.1.2]
JW0660  asnB; asparagine synthetase B [KO:K01953] [EC:6.3.5.4]
JW0812  iaaA; L-asparaginase [KO:K13051] [EC:3.5.1.1 3.4.19.5]
JW0911  aspC; aspartate aminotransferase, PLP-dependent [KO:K00813] [EC:2.6.1.1]
JW0999  putA; fused DNA-binding transcriptional regulator, proline dehydrogenase, and pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
JW1117  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
JW1295  puuE; GABA aminotransferase, PLP-dependent [KO:K00823] [EC:2.6.1.19]
JW1488  gadB; glutamate decarboxylase B, PLP-dependent [KO:K01580] [EC:4.1.1.15]
JW1517  yneH; predicted glutaminase [KO:K01425] [EC:3.5.1.2]
JW1750  gdhA; glutamate dehydrogenase, NADP-specific [KO:K00262] [EC:1.4.1.4]
JW1756  ansA; cytoplasmic L-asparaginase I [KO:K01424] [EC:3.5.1.1]
JW2287  yfbQ; predicted aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
JW2309  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
JW2558  nadB; quinolinate synthase, L-aspartate oxidase (B protein) subunit [KO:K00278] [EC:1.4.3.16]
JW2636  gabD; succinate-semialdehyde dehydrogenase I, NADP-dependent [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
JW2637  gabT; 4-aminobutyrate aminotransferase, PLP-dependent [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
JW2924  ansB; periplasmic L-asparaginase II [KO:K01424] [EC:3.5.1.1]
JW3140  argG; argininosuccinate synthetase [KO:K01940] [EC:6.3.4.5]
JW3179  gltB; glutamate synthase, large subunit [KO:K00265] [EC:1.4.1.13]
JW3180  gltD; glutamate synthase, 4Fe-4S protein, small subunit [KO:K00266] [EC:1.4.1.13]
JW3485  gadA; glutamate decarboxylase A, PLP-dependent [KO:K01580] [EC:4.1.1.15]
JW3707  glmS; L-glutamine:D-fructose-6-phosphate aminotransferase [KO:K00820] [EC:2.6.1.16]
JW3722  asnA; asparagine synthetase A [KO:K01914] [EC:6.3.1.1]
JW3841  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JW3932  argH; argininosuccinate lyase [KO:K01755] [EC:4.3.2.1]
JW4099  aspA; aspartate ammonia-lyase [KO:K01744] [EC:4.3.1.1]
JW4135  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
JW4203  pyrI; aspartate carbamoyltransferase, regulatory subunit [KO:K00610]
JW4204  pyrB; aspartate carbamoyltransferase, catalytic subunit [KO:K00609] [EC:2.1.3.2]
JW5019  yafV; predicted C-N hydrolase family amidase, NAD(P)-binding [KO:K13566] [EC:3.5.1.3]
JW5247  yneI; predicted aldehyde dehydrogenase [KO:K08324] [EC:1.2.1.16 1.2.1.24]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
ecj00010  Glycolysis / Gluconeogenesis
ecj00020  Citrate cycle (TCA cycle)
ecj00220  Arginine biosynthesis
ecj00230  Purine metabolism
ecj00240  Pyrimidine metabolism
ecj00260  Glycine, serine and threonine metabolism
ecj00261  Monobactam biosynthesis
ecj00300  Lysine biosynthesis
ecj00330  Arginine and proline metabolism
ecj00340  Histidine metabolism
ecj00410  beta-Alanine metabolism
ecj00460  Cyanoamino acid metabolism
ecj00470  D-Amino acid metabolism
ecj00480  Glutathione metabolism
ecj00520  Amino sugar and nucleotide sugar metabolism
ecj00620  Pyruvate metabolism
ecj00630  Glyoxylate and dicarboxylate metabolism
ecj00650  Butanoate metabolism
ecj00660  C5-Branched dibasic acid metabolism
ecj00760  Nicotinate and nicotinamide metabolism
ecj00770  Pantothenate and CoA biosynthesis
ecj00860  Porphyrin metabolism
ecj00910  Nitrogen metabolism
KO pathway
ko00250   

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