KEGG   PATHWAY: eco00620
Entry
eco00620                    Pathway                                
Name
Pyruvate metabolism - Escherichia coli K-12 MG1655
Class
Metabolism; Carbohydrate metabolism
Pathway map
eco00620  Pyruvate metabolism
eco00620

Module
eco_M00168  CAM (Crassulacean acid metabolism), dark [PATH:eco00620]
eco_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:eco00620]
eco_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:eco00620]
Other DBs
GO: 0006090
Organism
Escherichia coli K-12 MG1655 [GN:eco]
Gene
b0074  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
b0114  aceE; pyruvate dehydrogenase E1 component [KO:K00163] [EC:1.2.4.1]
b0115  aceF; pyruvate dehydrogenase, E2 subunit [KO:K00627] [EC:2.3.1.12]
b0116  lpd; lipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
b0185  accA; acetyl-CoA carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
b0212  gloB; hydroxyacylglutathione hydrolase GloB [KO:K01069] [EC:3.1.2.6]
b0325  yahK; aldehyde reductase, NADPH-dependent [KO:K13979] [EC:1.1.1.2]
b0351  mhpF; acetaldehyde dehydrogenase (acetylating) MhpF [KO:K04073] [EC:1.2.1.10]
b0356  frmA; S-(hydroxymethyl)glutathione dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
b0871  poxB; pyruvate oxidase [KO:K00156] [EC:1.2.5.1]
b0903  pflB; pyruvate formate-lyase [KO:K00656] [EC:2.3.1.54]
b0927  gloC; hydroxyacylglutathione hydrolase GloC [KO:K01069] [EC:3.1.2.6]
b0968  yccX; acylphosphatase [KO:K01512] [EC:3.6.1.7]
b1033  ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
b1241  adhE; fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE [KO:K04072] [EC:1.2.1.10 1.1.1.1]
b1378  ydbK; putative pyruvate-flavodoxin oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.7.-]
b1380  ldhA; D-lactate dehydrogenase [KO:K03778] [EC:1.1.1.28]
b1415  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
b1478  adhP; ethanol dehydrogenase/alcohol dehydrogenase [KO:K13953] [EC:1.1.1.1]
b1479  maeA; NAD(+)-dependent malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
b1611  fumC; fumarase C [KO:K01679] [EC:4.2.1.2]
b1612  fumA; fumarase A [KO:K01676] [EC:4.2.1.2]
b1651  gloA; glyoxalase I [KO:K01759] [EC:4.4.1.5]
b1675  fumD; fumarase D [KO:K01675]
b1676  pykF; pyruvate kinase I [KO:K00873] [EC:2.7.1.40]
b1702  ppsA; phosphoenolpyruvate synthetase [KO:K01007] [EC:2.7.9.2]
b1854  pykA; pyruvate kinase II [KO:K00873] [EC:2.7.1.40]
b1967  hchA; protein/nucleic acid deglycase 1 [KO:K05523] [EC:4.2.1.130 3.5.1.124]
b2133  dld; quinone-dependent D-lactate dehydrogenase [KO:K03777] [EC:1.1.5.12]
b2210  mqo; malate:quinone oxidoreductase [KO:K00116] [EC:1.1.5.4]
b2224  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
b2296  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
b2297  pta; phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
b2316  accD; acetyl-CoA carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
b2453  eutG; putative alcohol dehydrogenase EutG [KO:K04022]
b2455  eutE; acetaldehyde dehydrogenase (acetylating) EutE [KO:K04021]
b2458  eutD; phosphate acetyltransferase EutD [KO:K04020]
b2463  maeB; NADP(+)-dependent malate dehydrogenase [KO:K00029] [EC:1.1.1.40]
b2844  yqeF; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
b2929  fumE; fumarase E [KO:K01774]
b2976  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
b3114  tdcE; 2-ketobutyrate formate-lyase/pyruvate formate-lyase 4 [KO:K00656] [EC:2.3.1.54]
b3236  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
b3255  accB; biotin carboxyl carrier protein [KO:K02160]
b3256  accC; biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
b3403  pck; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
b3553  ghrB; glyoxylate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
b3588  aldB; aldehyde dehydrogenase B [KO:K00138] [EC:1.2.1.-]
b3589  yiaY; L-threonine dehydrogenase [KO:K13954] [EC:1.1.1.1]
b3605  lldD; L-lactate dehydrogenase [KO:K00101] [EC:1.1.2.3]
b3956  ppc; phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
b4014  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
b4069  acs; acetyl-CoA synthetase (AMP-forming) [KO:K01895] [EC:6.2.1.1]
b4122  fumB; fumarase B [KO:K01676] [EC:4.2.1.2]
b4151  frdD; fumarate reductase membrane protein FrdD [KO:K00247]
b4152  frdC; fumarate reductase membrane protein FrdC [KO:K00246]
b4153  frdB; fumarate reductase iron-sulfur protein [KO:K00245] [EC:1.3.5.1]
b4154  frdA; fumarate reductase flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
b4269  ahr; NADPH-dependent aldehyde reductase Ahr [KO:K12957] [EC:1.1.1.2 1.1.1.183]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
eco00010  Glycolysis / Gluconeogenesis
eco00020  Citrate cycle (TCA cycle)
eco00061  Fatty acid biosynthesis
eco00250  Alanine, aspartate and glutamate metabolism
eco00260  Glycine, serine and threonine metabolism
eco00290  Valine, leucine and isoleucine biosynthesis
eco00300  Lysine biosynthesis
eco00630  Glyoxylate and dicarboxylate metabolism
eco00640  Propanoate metabolism
eco00650  Butanoate metabolism
eco00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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