KEGG   PATHWAY: ecy00230
Entry
ecy00230                    Pathway                                
Name
Purine metabolism - Escherichia coli O152:H28 SE11 (commensal)
Class
Metabolism; Nucleotide metabolism
Pathway map
ecy00230  Purine metabolism
ecy00230

Module
ecy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ecy00230]
ecy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ecy00230]
ecy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ecy00230]
ecy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ecy00230]
ecy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ecy00230]
ecy_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ecy00230]
ecy_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ecy00230]
Other DBs
GO: 0006163 0042278
Organism
Escherichia coli O152:H28 SE11 (commensal) [GN:ecy]
Gene
ECSE_3315  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ECSE_3658  conserved hypothetical protein [KO:K08312] [EC:3.6.1.-]
ECSE_4658  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ECSE_3641  putative mutase [KO:K01839] [EC:5.4.2.7]
ECSE_0750  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
ECSE_1257  phosphoribosylpyrophosphate synthase [KO:K00948] [EC:2.7.6.1]
ECSE_2621  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ECSE_4294  phosphoribosylglycinamide synthase [KO:K01945] [EC:6.3.4.13]
ECSE_2786  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ECSE_2024  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
ECSE_2845  phosphoribosylformyl-glycineamide synthase [KO:K01952] [EC:6.3.5.3]
ECSE_2785  phosphoribosylaminoimidazole synthase [KO:K01933] [EC:6.3.3.1]
ECSE_0547  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
ECSE_0548  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
ECSE_2760  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ECSE_1197  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ECSE_4295  phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ECSE_0494  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ECSE_0505  UDP-sugar hydrolase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ECSE_2996  survival protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ECSE_0735  phosphatase NagD [KO:K02566] [EC:3.1.3.5]
ECSE_3661  putative hydrolase [KO:K20881] [EC:3.1.3.-]
ECSE_0502  inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
ECSE_2697  xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
ECSE_4659  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ECSE_0412  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ECSE_2879  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ECSE_0125  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ECSE_2794  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ECSE_2804  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ECSE_4670  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
ECSE_3222  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
ECSE_0258  xanthine guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ECSE_3130  conserved hypothetical protein [KO:K00087] [EC:1.17.1.4]
ECSE_3131  putative dehydrogenase [KO:K13479] [EC:1.17.1.4]
ECSE_3132  putative dehydrogenase [KO:K13480]
ECSE_0302  putative oxidoreductase [KO:K11177] [EC:1.17.1.4]
ECSE_0303  putative oxidoreductase [KO:K11178] [EC:1.17.1.4]
ECSE_0304  putative oxidoreductase [KO:K13483]
ECSE_2793  GMP synthase [KO:K01951] [EC:6.3.5.2]
ECSE_0105  GMP reductase [KO:K00364] [EC:1.7.1.7]
ECSE_3147  guanine deaminase [KO:K01487] [EC:3.5.4.3]
ECSE_3930  guanylate kinase [KO:K00942] [EC:2.7.4.8]
ECSE_2928  ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
ECSE_2495  ribonucleoside diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
ECSE_2929  ribonucleoside-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
ECSE_2496  ribonucleoside diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
ECSE_4543  anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ECSE_0161  deoxyguanosine triphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ECSE_2548  conserved hypothetical protein [KO:K08722] [EC:3.1.3.89]
ECSE_3932  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ECSE_2788  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ECSE_4061  guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ECSE_3042  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
ECSE_4087  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ECSE_4474  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ECSE_1744  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ECSE_2268  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ECSE_3055  conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ECSE_3949  putative adenine deaminase [KO:K01486] [EC:3.5.4.2]
ECSE_4519  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ECSE_0499  adenylate kinase [KO:K00939] [EC:2.7.4.3]
ECSE_3039  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
ECSE_3313  cAMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ECSE_0050  diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ECSE_3002  adenosine 5'-phosphosulfate kinase [KO:K00860] [EC:2.7.1.25]
ECSE_3003  ATP-sulfurylase large subunit [KO:K00956] [EC:2.7.7.4]
ECSE_3004  ATP-sulfurylase small subunit [KO:K00957] [EC:2.7.7.4]
ECSE_2199  conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
ECSE_0537  allantoinase [KO:K01466] [EC:3.5.2.5]
ECSE_0541  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
ECSE_0540  conserved hypothetical protein [KO:K14977] [EC:3.5.3.26]
ECSE_0531  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
ECSE_0542  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
ECSE_0546  putative carbamate kinase [KO:K00926] [EC:2.7.2.2]
ECSE_0343  carbamate kinase [KO:K00926] [EC:2.7.2.2]
ECSE_3138  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ecy00030  Pentose phosphate pathway
ecy00220  Arginine biosynthesis
ecy00250  Alanine, aspartate and glutamate metabolism
ecy00260  Glycine, serine and threonine metabolism
ecy00340  Histidine metabolism
ecy00630  Glyoxylate and dicarboxylate metabolism
ecy00730  Thiamine metabolism
ecy00740  Riboflavin metabolism
ecy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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