KEGG   PATHWAY: eee00330
Entry
eee00330                    Pathway                                
Name
Arginine and proline metabolism - Electrophorus electricus (electric eel)
Class
Metabolism; Amino acid metabolism
Pathway map
eee00330  Arginine and proline metabolism
eee00330

Module
eee_M00015  Proline biosynthesis, glutamate => proline [PATH:eee00330]
eee_M00047  Creatine pathway [PATH:eee00330]
eee_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:eee00330]
eee_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:eee00330]
eee_M00970  Proline degradation, proline => glutamate [PATH:eee00330]
eee_M00972  Proline metabolism [PATH:eee00330]
Other DBs
GO: 0006525 0006560
Organism
Electrophorus electricus (electric eel) [GN:eee]
Gene
113567973  [KO:K00472] [EC:1.14.11.2]
113568740  l3hypdh; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
113568800  [KO:K27382]
113569693  [KO:K27382]
113569715  [KO:K00128] [EC:1.2.1.3]
113569716  [KO:K00128] [EC:1.2.1.3]
113570097  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
113570208  sat1; diamine acetyltransferase 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
113570292  agmat; agmatinase, mitochondrial [KO:K27001]
113571536  pycr3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
113572073  [KO:K12259] [EC:1.5.3.16 1.5.3.-]
113572455  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
113573000  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
113573615  [KO:K14455] [EC:2.6.1.1]
113573768  [KO:K00657] [EC:2.3.1.57]
113573852  [KO:K00657] [EC:2.3.1.57]
113574379  [KO:K00274] [EC:1.4.3.4]
113574437  [KO:K05604] [EC:3.4.13.20]
113574537  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
113575010  ckmt2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
113575324  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
113576254  arg2; LOW QUALITY PROTEIN: arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
113576259  [KO:K00274] [EC:1.4.3.4]
113576807  [KO:K00286] [EC:1.5.1.2]
113576941  dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
113577205  [KO:K12259] [EC:1.5.3.16 1.5.3.-]
113577225  [KO:K12259] [EC:1.5.3.16 1.5.3.-]
113577297  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
113577671  aldh18a1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
113577699  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
113577767  nos1; LOW QUALITY PROTEIN: nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
113577787  [KO:K00318] [EC:1.5.5.2]
113578021  [KO:K00472] [EC:1.14.11.2]
113578030  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
113578385  [KO:K00933] [EC:2.7.3.2]
113578765  [KO:K14454] [EC:2.6.1.1]
113578998  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
113580269  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
113580646  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
113581120  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
113581285  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
113581568  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
113583152  [KO:K00128] [EC:1.2.1.3]
113585121  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
113585157  ckb; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
113585307  [KO:K00933] [EC:2.7.3.2]
113585466  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
113587485  p4ha1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
113587487  arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
113587524  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
113587645  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
113588955  [KO:K00472] [EC:1.14.11.2]
113589019  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
113589456  aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
113589697  [KO:K00286] [EC:1.5.1.2]
113589721  [KO:K27382]
113589937  amd1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
113591429  [KO:K13241] [EC:1.14.13.39]
113591591  lap3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
113591956  [KO:K00318] [EC:1.5.5.2]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
eee00020  Citrate cycle (TCA cycle)
eee00220  Arginine biosynthesis
eee00250  Alanine, aspartate and glutamate metabolism
eee00260  Glycine, serine and threonine metabolism
eee00270  Cysteine and methionine metabolism
eee00310  Lysine degradation
eee00410  beta-Alanine metabolism
eee00470  D-Amino acid metabolism
eee00480  Glutathione metabolism
eee00630  Glyoxylate and dicarboxylate metabolism
eee00650  Butanoate metabolism
eee00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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