KEGG   PATHWAY: els00330
Entry
els00330                    Pathway                                
Name
Arginine and proline metabolism - Esox lucius (northern pike)
Class
Metabolism; Amino acid metabolism
Pathway map
els00330  Arginine and proline metabolism
els00330

Module
els_M00015  Proline biosynthesis, glutamate => proline [PATH:els00330]
els_M00047  Creatine pathway [PATH:els00330]
els_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:els00330]
els_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:els00330]
els_M00970  Proline degradation, proline => glutamate [PATH:els00330]
els_M00972  Proline metabolism [PATH:els00330]
Other DBs
GO: 0006525 0006560
Organism
Esox lucius (northern pike) [GN:els]
Gene
105006462  [KO:K00472] [EC:1.14.11.2]
105006476  [KO:K01476] [EC:3.5.3.1]
105006876  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
105006879  [KO:K14454] [EC:2.6.1.1]
105006907  [KO:K27382]
105006908  [KO:K27382]
105007677  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
105008535  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
105009421  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
105010554  [KO:K00472] [EC:1.14.11.2]
105010633  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
105010795  sat2; spermidine/spermine N1-acetyltransferase family member 2 [KO:K00657] [EC:2.3.1.57]
105010858  sms; spermine synthase isoform X2 [KO:K00802] [EC:2.5.1.22]
105012029  [KO:K00286] [EC:1.5.1.2]
105012201  [KO:K00128] [EC:1.2.1.3]
105012659  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
105012696  [KO:K27382]
105012931  [KO:K00128] [EC:1.2.1.3]
105013040  [KO:K00286] [EC:1.5.1.2]
105013989  nos2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
105014085  [KO:K01581] [EC:4.1.1.17]
105014759  [KO:K00933] [EC:2.7.3.2]
105015538  ckb; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
105015940  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
105016125  [KO:K14455] [EC:2.6.1.1]
105017260  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
105017645  l3hypdh; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
105017895  amd1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
105019148  aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105019194  [KO:K05604] [EC:3.4.13.20]
105019195  [KO:K08660] [EC:3.4.13.18]
105019484  aoc1; amiloride-sensitive amine oxidase [copper-containing] isoform X2 [KO:K11182] [EC:1.4.3.22]
105020468  [KO:K00933] [EC:2.7.3.2]
105021076  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
105021383  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
105021749  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105021913  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
105021930  [KO:K00274] [EC:1.4.3.4]
105021992  [KO:K00657] [EC:2.3.1.57]
105022977  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
105023293  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
105023465  [KO:K14455] [EC:2.6.1.1]
105024174  [KO:K00274] [EC:1.4.3.4]
105024364  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
105025204  carns1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
105025337  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
105025596  dao; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
105026069  p4ha3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
105026394  pycr3; pyrroline-5-carboxylate reductase 3 isoform X3 [KO:K00286] [EC:1.5.1.2]
105026843  [KO:K27382]
105027064  [KO:K00318] [EC:1.5.5.2]
105027517  [KO:K00128] [EC:1.2.1.3]
105027680  [KO:K00657] [EC:2.3.1.57]
105028254  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
105028550  [KO:K00933] [EC:2.7.3.2]
105028693  agmat; agmatinase, mitochondrial [KO:K27001]
105029301  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
105030670  aldh9a1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
105031277  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
105031445  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
105031480  sat2; diamine acetyltransferase 2 isoform X1 [KO:K00657] [EC:2.3.1.57]
109615805  [KO:K13241] [EC:1.14.13.39]
114840664  [KO:K01581] [EC:4.1.1.17]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
els00020  Citrate cycle (TCA cycle)
els00220  Arginine biosynthesis
els00250  Alanine, aspartate and glutamate metabolism
els00260  Glycine, serine and threonine metabolism
els00270  Cysteine and methionine metabolism
els00310  Lysine degradation
els00410  beta-Alanine metabolism
els00470  D-Amino acid metabolism
els00480  Glutathione metabolism
els00630  Glyoxylate and dicarboxylate metabolism
els00650  Butanoate metabolism
els00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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