KEGG   PATHWAY: geh00630
Entry
geh00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Gemmobacter aquarius
Class
Metabolism; Carbohydrate metabolism
Pathway map
geh00630  Glyoxylate and dicarboxylate metabolism
geh00630

Module
geh_M00373  Ethylmalonyl pathway [PATH:geh00630]
geh_M00621  Glycine cleavage system [PATH:geh00630]
geh_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:geh00630]
Other DBs
GO: 0046487 0043648
Organism
Gemmobacter aquarius [GN:geh]
Gene
HYN69_15525  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HYN69_07090  malate synthase G [KO:K01638] [EC:2.3.3.9]
HYN69_13125  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HYN69_07315  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
HYN69_11095  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
HYN69_16140  succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
HYN69_16135  ADP-forming succinate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
HYN69_11875  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
HYN69_15060  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HYN69_15760  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HYN69_15055  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
HYN69_15935  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
HYN69_12810  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
HYN69_12845  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
HYN69_12825  protein meaA [KO:K14447] [EC:5.4.99.63]
HYN69_01605  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
HYN69_13100  hypothetical protein [KO:K14449] [EC:4.2.1.148]
HYN69_16155  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
HYN69_16130  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
HYN69_13115  CoA ester lyase [KO:K14451] [EC:3.1.2.30]
HYN69_05090  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
HYN69_05065  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
HYN69_05100  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
HYN69_02480  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
HYN69_02475  2-hydroxy-acid oxidase [KO:K11472] [EC:1.1.99.14]
HYN69_02470  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
HYN69_18750  catalase HPII [KO:K03781] [EC:1.11.1.6]
HYN69_13795  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
HYN69_13745  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
HYN69_04940  phosphatase [KO:K01091] [EC:3.1.3.18]
HYN69_05760  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
HYN69_06980  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
HYN69_16125  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
HYN69_00885  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
HYN69_05620  aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
HYN69_03795  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HYN69_03805  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HYN69_13765  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HYN69_13825  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HYN69_11050  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
HYN69_13395  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HYN69_15090  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HYN69_13685  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
HYN69_13675  glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
HYN69_06785  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
HYN69_06805  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
HYN69_07775  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HYN69_13170  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HYN69_13680  gcvH; glycine cleavage system protein GcvH [KO:K02437]
HYN69_07105  glycerate kinase [KO:K11529] [EC:2.7.1.165]
HYN69_09280  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
HYN69_00260  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
HYN69_00250  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
HYN69_00240  formate dehydrogenase [KO:K00124]
HYN69_00235  formate dehydrogenase subunit gamma [KO:K00127]
HYN69_02435  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
HYN69_19125  acetamidase [KO:K01455] [EC:3.5.1.49]
HYN69_18235  hypothetical protein [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
geh00010  Glycolysis / Gluconeogenesis
geh00020  Citrate cycle (TCA cycle)
geh00030  Pentose phosphate pathway
geh00053  Ascorbate and aldarate metabolism
geh00071  Fatty acid degradation
geh00230  Purine metabolism
geh00250  Alanine, aspartate and glutamate metabolism
geh00260  Glycine, serine and threonine metabolism
geh00620  Pyruvate metabolism
geh00750  Vitamin B6 metabolism
geh00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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