KEGG   PATHWAY: gwc00230
Entry
gwc00230                    Pathway                                
Name
Purine metabolism - Geobacillus sp. WCH70
Class
Metabolism; Nucleotide metabolism
Pathway map
gwc00230  Purine metabolism
gwc00230

Module
gwc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:gwc00230]
gwc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:gwc00230]
gwc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gwc00230]
gwc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:gwc00230]
gwc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:gwc00230]
Other DBs
GO: 0006163 0042278
Organism
Geobacillus sp. WCH70 [GN:gwc]
Gene
GWCH70_2263  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
GWCH70_2256  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
GWCH70_0528  Phosphomannomutase [KO:K01835] [EC:5.4.2.2]
GWCH70_0362  Phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
GWCH70_0046  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
GWCH70_0260  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
GWCH70_0264  phosphoribosylamine/glycine ligase [KO:K01945] [EC:6.3.4.13]
GWCH70_0262  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
GWCH70_0259  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
GWCH70_0257  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
GWCH70_0258  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
GWCH70_0261  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
GWCH70_0254  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
GWCH70_0253  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
GWCH70_0256  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
GWCH70_0255  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
GWCH70_0263  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GWCH70_2511  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
GWCH70_2912  metallophosphoesterase [KO:K01081] [EC:3.1.3.5]
GWCH70_2255  purine nucleoside phosphorylase I, inosine and guanosine-specific [KO:K03783] [EC:2.4.2.1]
GWCH70_1863  purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
GWCH70_1033  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GWCH70_0063  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
GWCH70_0009  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
GWCH70_2148  Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
GWCH70_2744  protein of unknown function DUF84 [KO:K01529] [EC:3.6.1.73]
GWCH70_2599  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
GWCH70_0237  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
GWCH70_1058  guanylate kinase [KO:K00942] [EC:2.7.4.8]
GWCH70_0597  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
GWCH70_0596  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
GWCH70_0016  deoxynucleoside kinase [KO:K15518] [EC:2.7.1.113]
GWCH70_2510  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GWCH70_0775  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
GWCH70_3410  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
GWCH70_0015  deoxynucleoside kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
GWCH70_0266  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
GWCH70_1192  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
GWCH70_0132  adenylate kinase [KO:K00939] [EC:2.7.4.3]
GWCH70_0411  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
GWCH70_0412  sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
GWCH70_3176  amidase, hydantoinase/carbamoylase family [KO:K02083] [EC:3.5.3.9]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
gwc00030  Pentose phosphate pathway
gwc00220  Arginine biosynthesis
gwc00250  Alanine, aspartate and glutamate metabolism
gwc00260  Glycine, serine and threonine metabolism
gwc00340  Histidine metabolism
gwc00630  Glyoxylate and dicarboxylate metabolism
gwc00730  Thiamine metabolism
gwc00740  Riboflavin metabolism
gwc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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