Homo sapiens (human): 6776
Help
Entry
6776 CDS
T01001
Symbol
STAT5A, MGF, STAT5
Name
(RefSeq) signal transducer and activator of transcription 5A
KO
K11223
signal transducer and activator of transcription 5A
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04217
Necroptosis
hsa04630
JAK-STAT signaling pathway
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa04917
Prolactin signaling pathway
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa04935
Growth hormone synthesis, secretion and action
hsa05161
Hepatitis B
hsa05162
Measles
hsa05166
Human T-cell leukemia virus 1 infection
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05207
Chemical carcinogenesis - receptor activation
hsa05220
Chronic myeloid leukemia
hsa05221
Acute myeloid leukemia
hsa05223
Non-small cell lung cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06162
Hepatitis B virus (HBV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06219
JAK-STAT signaling (cancer)
nt06262
Pancreatic cancer
nt06263
Hepatocellular carcinoma
nt06266
Non-small cell lung cancer
nt06275
Acute myeloid leukemia
nt06276
Chronic myeloid leukemia
nt06324
GHRH-GH-IGF signaling
nt06325
Hormone/cytokine signaling
nt06518
JAK-STAT signaling
nt06527
Necroptosis
Element
N00053
Cytokine-Jak-STAT signaling pathway
N00054
Duplication or mutation-activated FLT3 to Jak-STAT signaling pathway
N00055
BCR-ABL fusion kinase to Jak-STAT signaling pathway
N00094
EGF-Jak-STAT signaling pathway
N00105
EML4-ALK fusion kinase to Jak-STAT signaling pathway
N00219
FLT3LG-FLT3-STAT5 signaling pathway
N00491
HTLV-1 p12 to Jak-STAT signaling pathway
N00907
GH-Jak-STAT signaling pathway
N00920
PRL-JAK-STAT signaling pathway
N01554
IL2 family to Jak-STAT signaling pathway
N01555
Hormone-like-cytokine to Jak-STAT signaling pathway
N01662
IFN-RIPK1/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
6776 (STAT5A)
04630 JAK-STAT signaling pathway
6776 (STAT5A)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
6776 (STAT5A)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
6776 (STAT5A)
04659 Th17 cell differentiation
6776 (STAT5A)
09152 Endocrine system
04917 Prolactin signaling pathway
6776 (STAT5A)
04935 Growth hormone synthesis, secretion and action
6776 (STAT5A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6776 (STAT5A)
05207 Chemical carcinogenesis - receptor activation
6776 (STAT5A)
05203 Viral carcinogenesis
6776 (STAT5A)
09162 Cancer: specific types
05221 Acute myeloid leukemia
6776 (STAT5A)
05220 Chronic myeloid leukemia
6776 (STAT5A)
05223 Non-small cell lung cancer
6776 (STAT5A)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
6776 (STAT5A)
05161 Hepatitis B
6776 (STAT5A)
05162 Measles
6776 (STAT5A)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
6776 (STAT5A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6776 (STAT5A)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
STAT
6776 (STAT5A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
STAT_bind
STAT_alpha
STAT_int
STAT_linker
SH2
Motif
Other DBs
NCBI-GeneID:
6776
NCBI-ProteinID:
NP_001275647
OMIM:
601511
HGNC:
11366
Ensembl:
ENSG00000126561
UniProt:
P42229
A0A384N5W4
A8K6I5
Q59GY7
Structure
PDB
LinkDB
All DBs
Position
17:42287439..42311943
Genome browser
AA seq
794 aa
AA seq
DB search
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLV
REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL
GDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATY
MDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLS
PPAGLFTSARGSLS
NT seq
2385 nt
NT seq
+upstream
nt +downstream
nt
atggcgggctggatccaggcccagcagctgcagggagacgcgctgcgccagatgcaggtg
ctgtacggccagcacttccccatcgaggtccggcactacttggcccagtggattgagagc
cagccatgggatgccattgacttggacaatccccaggacagagcccaagccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg
tttttactgaagatcaagctggggcactacgccacgcagctccagaaaacatatgaccgc
tgccccctggagctggtccgctgcatccggcacattctgtacaatgaacagaggctggtc
cgagaagccaacaattgcagctctccggctgggatcctggttgacgccatgtcccagaag
caccttcagatcaaccagacatttgaggagctgcgactggtcacgcaggacacagagaat
gagctgaagaaactgcagcagactcaggagtacttcatcatccagtaccaggagagcctg
aggatccaagctcagtttgcccagctggcccagctgagcccccaggagcgtctgagccgg
gagacggccctccagcagaagcaggtgtctctggaggcctggttgcagcgtgaggcacag
acactgcagcagtaccgcgtggagctggccgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggatgacgagctgatccagtggaagcggcggcagcag
ctggccgggaacggcgggccccccgagggcagcctggacgtgctacagtcctggtgtgag
aagttggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctctgc
cagcagctgcccatccccggcccagtggaggagatgctggccgaggtcaacgccaccatc
acggacattatctcagccctggtgaccagcacattcatcattgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcagccaccgtacgcctgctggtgggcgggaagctg
aacgtgcacatgaatcccccccaggtgaaggccaccatcatcagtgagcagcaggccaag
tctctgcttaaaaatgagaacacccgcaacgagtgcagtggtgagatcctgaacaactgc
tgcgtgatggagtaccaccaagccacgggcaccctcagtgcccacttcaggaacatgtca
ctgaagaggatcaagcgtgctgaccggcggggtgcagagtccgtgacagaggagaagttc
acagtcctgtttgagtctcagttcagtgttggcagcaatgagcttgtgttccaggtgaag
actctgtccctacctgtggttgtcatcgtccacggcagccaggaccacaatgccacggct
actgtgctgtgggacaatgcctttgctgagccgggcagggtgccatttgccgtgcctgac
aaagtgctgtggccgcagctgtgtgaggcgctcaacatgaaattcaaggccgaagtgcag
agcaaccggggcctgaccaaggagaacctcgtgttcctggcgcagaaactgttcaacaac
agcagcagccacctggaggactacagtggcctgtccgtgtcctggtcccagttcaacagg
gagaacttgccgggctggaactacaccttctggcagtggtttgacggggtgatggaggtg
ttgaagaagcaccacaagccccactggaatgatggggccatcctaggttttgtgaataag
caacaggcccacgacctgctcatcaacaagcccgacgggaccttcttgttgcgctttagt
gactcagaaatcgggggcatcaccatcgcctggaagtttgactccccggaacgcaacctg
tggaacctgaaaccattcaccacgcgggatttctccatcaggtccctggctgaccggctg
ggggacctgagctatctcatctatgtgtttcctgaccgccccaaggatgaggtcttctcc
aagtactacactcctgtgctggctaaagctgttgatggatatgtgaaaccacagatcaag
caagtggtccctgagtttgtgaatgcatctgcagatgctgggggcagcagcgccacgtac
atggaccaggccccctccccagctgtgtgcccccaggctccctataacatgtacccacag
aaccctgaccatgtactcgatcaggatggagaattcgacctggatgagaccatggatgtg
gccaggcacgtggaggaactcttacgccgaccaatggacagtcttgactcccgcctctcg
ccccctgccggtcttttcacctctgccagaggctccctctcatga
Homo sapiens (human): 6777
Help
Entry
6777 CDS
T01001
Symbol
STAT5B, GHISID2, STAT5
Name
(RefSeq) signal transducer and activator of transcription 5B
KO
K11224
signal transducer and activator of transcription 5B
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04062
Chemokine signaling pathway
hsa04217
Necroptosis
hsa04630
JAK-STAT signaling pathway
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa04917
Prolactin signaling pathway
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa04935
Growth hormone synthesis, secretion and action
hsa05161
Hepatitis B
hsa05162
Measles
hsa05166
Human T-cell leukemia virus 1 infection
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05207
Chemical carcinogenesis - receptor activation
hsa05220
Chronic myeloid leukemia
hsa05221
Acute myeloid leukemia
hsa05223
Non-small cell lung cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06162
Hepatitis B virus (HBV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06219
JAK-STAT signaling (cancer)
nt06262
Pancreatic cancer
nt06263
Hepatocellular carcinoma
nt06266
Non-small cell lung cancer
nt06275
Acute myeloid leukemia
nt06276
Chronic myeloid leukemia
nt06324
GHRH-GH-IGF signaling
nt06325
Hormone/cytokine signaling
nt06518
JAK-STAT signaling
Element
N00053
Cytokine-Jak-STAT signaling pathway
N00054
Duplication or mutation-activated FLT3 to Jak-STAT signaling pathway
N00055
BCR-ABL fusion kinase to Jak-STAT signaling pathway
N00094
EGF-Jak-STAT signaling pathway
N00105
EML4-ALK fusion kinase to Jak-STAT signaling pathway
N00219
FLT3LG-FLT3-STAT5 signaling pathway
N00491
HTLV-1 p12 to Jak-STAT signaling pathway
N00907
GH-Jak-STAT signaling pathway
N00920
PRL-JAK-STAT signaling pathway
N01554
IL2 family to Jak-STAT signaling pathway
N01555
Hormone-like-cytokine to Jak-STAT signaling pathway
Disease
H00931
Growth hormone insensitivity with immunodeficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
6777 (STAT5B)
04630 JAK-STAT signaling pathway
6777 (STAT5B)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
6777 (STAT5B)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
6777 (STAT5B)
04659 Th17 cell differentiation
6777 (STAT5B)
04062 Chemokine signaling pathway
6777 (STAT5B)
09152 Endocrine system
04917 Prolactin signaling pathway
6777 (STAT5B)
04935 Growth hormone synthesis, secretion and action
6777 (STAT5B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6777 (STAT5B)
05207 Chemical carcinogenesis - receptor activation
6777 (STAT5B)
05203 Viral carcinogenesis
6777 (STAT5B)
09162 Cancer: specific types
05221 Acute myeloid leukemia
6777 (STAT5B)
05220 Chronic myeloid leukemia
6777 (STAT5B)
05223 Non-small cell lung cancer
6777 (STAT5B)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
6777 (STAT5B)
05161 Hepatitis B
6777 (STAT5B)
05162 Measles
6777 (STAT5B)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
6777 (STAT5B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6777 (STAT5B)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
STAT
6777 (STAT5B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
STAT_bind
STAT_alpha
STAT_int
STAT_linker
SH2
Motif
Other DBs
NCBI-GeneID:
6777
NCBI-ProteinID:
NP_036580
OMIM:
604260
HGNC:
11367
Ensembl:
ENSG00000173757
UniProt:
P51692
Structure
PDB
LinkDB
All DBs
Position
17:complement(42199177..42288370)
Genome browser
AA seq
787 aa
AA seq
DB search
MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG
GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ
WIPHAQS
NT seq
2364 nt
NT seq
+upstream
nt +downstream
nt
atggctgtgtggatacaagctcagcagctccaaggagaagcccttcatcagatgcaagcg
ttatatggccagcattttcccattgaggtgcggcattatttatcccagtggattgaaagc
caagcatgggactcagtagatcttgataatccacaggagaacattaaggccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcagagcaccaggtgggggaagatggg
tttttactgaagatcaagctggggcactatgccacacagctccagaacacgtatgaccgc
tgccccatggagctggtccgctgcatccgccatatattgtacaatgaacagaggttggtc
cgagaagccaacaatggtagctctccagctggaagccttgctgatgccatgtcccagaaa
cacctccagatcaaccagacgtttgaggagctgcgactggtcacgcaggacacagagaat
gagttaaaaaagctgcagcagactcaggagtacttcatcatccagtaccaggagagcctg
aggatccaagctcagtttggcccgctggcccagctgagcccccaggagcgtctgagccgg
gagacggccctccagcagaagcaggtgtctctggaggcctggttgcagcgtgaggcacag
acactgcagcagtaccgcgtggagctggccgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggatgacgagctgatccagtggaagcggcggcagcag
ctggccgggaacggcgggccccccgagggcagcctggacgtgctacagtcctggtgtgag
aagttggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctctgc
cagcagctgcccatccccggcccagtggaggagatgctggccgaggtcaacgccaccatc
acggacattatctcagccctggtgaccagcacgttcatcattgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcagccactgtgcgcctgctggtgggcgggaagctg
aacgtgcacatgaaccccccccaggtgaaggccaccatcatcagtgagcagcaggccaag
tctctgctcaagaacgagaacacccgcaatgattacagtggcgagatcttgaacaactgc
tgcgtcatggagtaccaccaagccacaggcacccttagtgcccacttcaggaatatgtcc
ctgaaacgaattaagaggtcagaccgtcgtggggcagagtcggtgacagaagaaaaattt
acaatcctgtttgaatcccagttcagtgttggtggaaatgagctggtttttcaagtcaag
accctgtccctgccagtggtggtgatcgttcatggcagccaggacaacaatgcgacggcc
actgttctctgggacaatgcttttgcagagcctggcagggtgccatttgccgtgcctgac
aaagtgctgtggccacagctgtgtgaggcgctcaacatgaaattcaaggccgaagtgcag
agcaaccggggcctgaccaaggagaacctcgtgttcctggcgcagaaactgttcaacaac
agcagcagccacctggaggactacagtggcctgtctgtgtcctggtcccagttcaacagg
gagaatttaccaggacggaattacactttctggcaatggtttgacggtgtgatggaagtg
ttaaaaaaacatctcaagcctcattggaatgatggggccattttggggtttgtaaacaag
caacaggcccatgacctactcattaacaagccagatgggaccttcctcctgagattcagt
gactcagaaattggcggcatcaccattgcttggaagtttgattctcaggaaagaatgttt
tggaatctgatgccttttaccaccagagacttctccattcggtccctagccgaccgcttg
ggagacttgaattaccttatctacgtgtttcctgatcggccaaaagatgaagtatactcc
aaatactacacaccagttccctgcgagtctgctactgctaaagctgttgatggatacgtg
aagccacagatcaagcaagtggtccctgagtttgtgaacgcatctgcagatgccgggggc
ggcagcgccacgtacatggaccaggccccctccccagctgtgtgtccccaggctcactat
aacatgtacccacagaaccctgactcagtccttgacaccgatggggacttcgatctggag
gacacaatggacgtagcgcggcgtgtggaggagctcctgggccggccaatggacagtcag
tggatcccgcacgcacaatcgtga
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integrated database retrieval system
