Homo sapiens (human): 1814
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Entry
1814 CDS
T01001
Symbol
DRD3, D3DR, ETM1, FET1
Name
(RefSeq) dopamine receptor D3
KO
K04146
dopamine receptor D3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04081
Hormone signaling
hsa04082
Neuroactive ligand signaling
hsa04728
Dopaminergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01898
Dopamine-DRD-GNAI/O signaling pathway
Disease
H01577
Essential tremor
H01649
Schizophrenia
Drug target
Amisulpride:
D07310
<US>
Aplindore fumarate:
D03214
Aripiprazole (
DG00906
):
D01164
<JP/US>
D10355
D10364
<US>
D10516
<JP/US>
Blonanserin:
D01176
<JP>
Captodiame:
D07316
Dexpramipexole (
DG01331
):
D09886
D09887
Dopamine (
DG00213
):
D00633
<JP/US>
D07870
Dopexamine (
DG00222
):
D03891
D03892
Etilevodopa:
D04097
Foslevodopa:
D11839
Levodopa:
D00059
<JP/US>
Lisuride (
DG00453
):
D01462
D08132
Olanzapine (
DG00898
):
D00454
<JP/US>
D06623
<US>
Oxiperomide:
D02676
Pardoprunox (
DG01324
):
D09366
D09397
Piribedil:
D07305
Pramipexole (
DG00863
):
D00559
<JP/US>
D05575
Quinpirole hydrochloride:
D05682
Ropinirole (
DG00862
):
D00784
<JP/US>
D08489
Tiotixene (
DG00895
):
D00374
<US>
D02612
Trazpiroben:
D11982
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1814 (DRD3)
04082 Neuroactive ligand signaling
1814 (DRD3)
04081 Hormone signaling
1814 (DRD3)
09150 Organismal Systems
09156 Nervous system
04728 Dopaminergic synapse
1814 (DRD3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
1814 (DRD3)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Dopamine
1814 (DRD3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7TM_GPCR_Srx
7tm_4
Motif
Other DBs
NCBI-GeneID:
1814
NCBI-ProteinID:
NP_000787
OMIM:
126451
HGNC:
3024
Ensembl:
ENSG00000151577
UniProt:
P35462
A8K8E4
X5D2G4
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(114127580..114199407)
Genome browser
AA seq
400 aa
AA seq
DB search
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atggcatctctgagccagctgagtggccacctgaactacacctgtggggcagagaactcc
acaggtgccagccaggcccgcccacatgcctactatgccctctcctactgcgcgctcatc
ctggccatcgtcttcggcaatggcctggtgtgcatggctgtgctgaaggagcgggccctg
cagactaccaccaactacttagtagtgagcctggctgtggcagacttgctggtggccacc
ttggtgatgccctgggtggtatacctggaggtgacaggtggagtctggaatttcagccgc
atttgctgtgatgtttttgtcaccctggatgtcatgatgtgtacagccagcatccttaat
ctctgtgccatcagcatagacaggtacactgcagtggtcatgcccgttcactaccagcat
ggcacgggacagagctcctgtcggcgcgtggccctcatgatcacggccgtctgggtactg
gcctttgctgtgtcctgccctcttctgtttggctttaataccacaggggaccccactgtc
tgctccatctccaaccctgattttgtcatctactcttcagtggtgtccttctacctgccc
tttggagtgactgtccttgtctatgccagaatctatgtggtgctgaaacaaaggagacgg
aaaaggatcctcactcgacagaacagtcagtgcaacagtgtcaggcctggcttcccccag
caaaccctctctcctgacccggcacatctggagctgaagcgttactacagcatctgccag
gacactgccttgggtggaccaggcttccaagaaagaggaggagagttgaaaagagaggag
aagactcggaattccctgagtcccaccatagcgcccaagctcagcttagaagttcgaaaa
ctcagcaatggcagattatcgacatctttgaagctggggcccctgcaacctcggggagtg
ccacttcgggagaagaaggcaacccaaatggtggccattgtgcttggggccttcattgtc
tgctggctgcccttcttcttgacccatgttctcaatacccactgccagacatgccacgtg
tccccagagctttacagtgccacgacatggctgggctacgtgaatagcgccctcaaccct
gtgatctataccaccttcaatatcgagttccggaaagccttcctcaagatcctgtcttgc
tga
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