KEGG   PATHWAY: ko00625
Entry
ko00625                     Pathway                                
Name
Chloroalkane and chloroalkene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
ko00625  Chloroalkane and chloroalkene degradation
ko00625

Other DBs
UMBBD: tce tce2 tca atl dcm dce cpr caa
Orthology
K00001  E1.1.1.1, adh; alcohol dehydrogenase [EC:1.1.1.1]
K00114  exaA; alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8]
K00121  frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00128  ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00148  fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
K00531  anfG; nitrogenase delta subunit [EC:1.18.6.1]
K01560  E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
K01561  dehH; haloacetate dehalogenase [EC:3.8.1.3]
K01563  dhaA; haloalkane dehalogenase [EC:3.8.1.5]
K02586  nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
K02588  nifH; nitrogenase iron protein NifH
K02591  nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha [EC:1.14.12.3 1.14.12.11 1.14.12.26]
K04072  adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K13953  adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
K13954  yiaY; alcohol dehydrogenase [EC:1.1.1.1]
K14028  mdh1, mxaF; methanol dehydrogenase (cytochrome c) subunit 1 [EC:1.1.2.7]
K14029  mdh2, mxaI; methanol dehydrogenase (cytochrome c) subunit 2 [EC:1.1.2.7]
K14419  caaD1; alpha-subunit of trans-3-chloroacrylic acid dehalogenase [EC:3.8.1.-]
K14420  caaD2; beta-subunit of trans-3-chloroacrylic acid dehalogenase [EC:3.8.1.-]
K14421  cis-caaD; cis-3-chloroacrylic acid dehalogenase [EC:3.8.1.-]
K14422  msaD; malonate semialdehyde decarboxylase [EC:4.1.1.-]
K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta [EC:1.14.12.3 1.14.12.11 1.14.12.26]
K17067  mdo; formaldehyde dismutase / methanol dehydrogenase [EC:1.2.98.1 1.1.99.37]
K17068  fdm; formaldehyde dismutase [EC:1.2.98.1]
K17070  dcmA; dichloromethane dehalogenase [EC:4.5.1.3]
K18089  todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component
K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component [EC:1.18.1.3 1.18.1.-]
K20625  ahy; acetylene hydratase [EC:4.2.1.112]
K21647  pceA; tetrachloroethene reductive dehalogenase [EC:1.21.99.5]
K21648  pceB; tetrachloroethene reductive dehalogenase membrane anchor
K22353  etnC; alkene monooxygenase alpha subunit [EC:1.14.13.69]
K22354  etnA; alkene monooxygenase beta subunit [EC:1.14.13.69]
K22355  etnB; alkene monooxygenase coupling protein
K22356  etnD; alkene monooxygenase reductase
K22357  amoA; alkene monooxygenase alpha subunit [EC:1.14.13.69]
K22358  amoE; alkene monooxygenase beta subunit [EC:1.14.13.69]
K22359  amoB; alkene monooxygenase gamma subunit [EC:1.14.13.69]
K22360  amoC; alkene monooxygenase ferredoxin subunit
K22361  amoD; alkene monooxygenase effector subunit
K22362  amoF; alkene monooxygenase ferredoxin reductase component [EC:1.18.1.3]
K22363  etnE; 2-hydroxypropyl-CoM lyase [EC:4.4.1.23]
Compound
C00011  CO2
C00024  Acetyl-CoA
C00048  Glyoxylate
C00058  Formate
C00067  Formaldehyde
C00084  Acetaldehyde
C00160  Glycolate
C00209  Oxalate
C00222  3-Oxopropanoate
C00237  CO
C01380  Ethylene glycol
C01548  Acetylene
C02271  Dichloromethane
C06547  Ethylene
C06548  Ethylene oxide
C06609  trans-1,3-Dichloropropene
C06610  cis-1,3-Dichloropropene
C06611  trans-3-Chloro-2-propene-1-ol
C06612  cis-3-Chloro-2-propene-1-ol
C06613  trans-3-Chloroallyl aldehyde
C06614  trans-3-Chloroacrylic acid
C06615  cis-3-Chloroacrylic acid
C06752  1,2-Dichloroethane
C06753  2-Chloroethanol
C06754  Chloroacetaldehyde
C06755  Chloroacetic acid
C06789  Tetrachloroethene
C06790  Trichloroethene
C06791  trans-1,2-Dichloroethene
C06792  cis-1,2-Dichloroethene
C06793  Vinyl chloride
C07490  Trichloroethanol
C11148  TCE epoxide
C11149  Dichloroacetate
C11150  Trichloroacetate
C14866  Chloral
C16348  cis-3-Chloroallyl aldehyde
C18246  1,1,1-Trichloroethane
C18247  1,1-Dichloroethane
C18248  Chloroethane
C20303  Chloroethylene oxide
C21752  2-Hydroxyethyl-CoM
C21753  2-Chloro-2-hydroxyethyl-CoM
Reference
PMID:15294827
  Authors
Muller JA, Rosner BM, Von Abendroth G, Meshulam-Simon G, McCarty PL, Spormann AM.
  Title
Molecular identification of the catabolic vinyl chloride reductase from Dehalococcoides sp. strain VS and its environmental distribution.
  Journal
Appl Environ Microbiol 70:4880-8 (2004)
DOI:10.1128/AEM.70.8.4880-4888.2004
Reference
PMID:16957242
  Authors
Lee PK, Johnson DR, Holmes VF, He J, Alvarez-Cohen L.
  Title
Reductive dehalogenase gene expression as a biomarker for physiological activity of Dehalococcoides spp.
  Journal
Appl Environ Microbiol 72:6161-8 (2006)
DOI:10.1128/AEM.01070-06
Reference
PMID:15865156
  Authors
Torz M, Beschkov V
  Title
Biodegradation of monochloroacetic acid used as a sole carbon and energy source by Xanthobacter autotrophicus GJ10 strain in batch and continuous culture.
  Journal
Biodegradation 16:423-33 (2005)
DOI:10.1007/s10532-004-3614-8
Reference
PMID:10347028
  Authors
Hage JC, Hartmans S
  Title
Monooxygenase-mediated 1,2-dichloroethane degradation by Pseudomonas sp. strain DCA1.
  Journal
Appl Environ Microbiol 65:2466-70 (1999)
DOI:10.1128/AEM.65.6.2466-2470.1999
Reference
PMID:9687453
  Authors
Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB.
  Title
Degradation of 1,3-dichloropropene by pseudomonas cichorii 170.
  Journal
Appl Environ Microbiol 64:2931-6 (1998)
DOI:10.1128/AEM.64.8.2931-2936.1998
Reference
PMID:12411705
  Authors
Sun B, Griffin BM, Ayala-del-Rio HL, Hashsham SA, Tiedje JM
  Title
Microbial dehalorespiration with 1,1,1-trichloroethane.
  Journal
Science 298:1023-5 (2002)
DOI:10.1126/science.1074675
Reference
PMID:11999413
  Authors
Hashimoto A, Iwasaki K, Nakasugi N, Nakajima M, Yagi O
  Title
Degradation pathways of trichloroethylene and 1,1,1-trichloroethane by Mycobacterium sp. TA27.
  Journal
Biosci Biotechnol Biochem 66:385-90 (2002)
DOI:10.1271/bbb.66.385
Reference
PMID:1768109
  Authors
Newman LM, Wackett LP
  Title
Fate of 2,2,2-trichloroacetaldehyde (chloral hydrate) produced during trichloroethylene oxidation by methanotrophs.
  Journal
Appl Environ Microbiol 57:2399-402 (1991)
DOI:10.1128/AEM.57.8.2399-2402.1991
Reference
PMID:8981984
  Authors
Newman LM, Wackett LP
  Title
Trichloroethylene oxidation by purified toluene 2-monooxygenase: products, kinetics, and turnover-dependent inactivation.
  Journal
J Bacteriol 179:90-6 (1997)
DOI:10.1128/JB.179.1.90-96.1997
Related
pathway
ko00620  Pyruvate metabolism
ko00630  Glyoxylate and dicarboxylate metabolism
ko00680  Methane metabolism

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