KEGG   PATHWAY: lcat00330
Entry
lcat00330                   Pathway                                
Name
Arginine and proline metabolism - Lemur catta (Ring-tailed lemur)
Class
Metabolism; Amino acid metabolism
Pathway map
lcat00330  Arginine and proline metabolism
lcat00330

Module
lcat_M00015  Proline biosynthesis, glutamate => proline [PATH:lcat00330]
lcat_M00047  Creatine pathway [PATH:lcat00330]
lcat_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:lcat00330]
lcat_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:lcat00330]
lcat_M00970  Proline degradation, proline => glutamate [PATH:lcat00330]
lcat_M00972  Proline metabolism [PATH:lcat00330]
Other DBs
GO: 0006525 0006560
Organism
Lemur catta (Ring-tailed lemur) [GN:lcat]
Gene
123620296  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
123621854  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
123621855  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
123622168  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
123622560  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
123623960  CKM; creatine kinase M-type [KO:K27382]
123624454  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
123625257  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
123625902  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
123626041  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
123626251  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
123626285  [KO:K00318] [EC:1.5.5.2]
123626687  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
123627528  PYCR2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
123628641  [KO:K14455] [EC:2.6.1.1]
123630540  CKMT1A; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
123632776  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
123633163  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
123633263  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
123634483  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
123634927  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
123635811  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
123635916  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
123635956  AGMAT; agmatinase, mitochondrial [KO:K27001]
123636594  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
123637323  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
123637477  [KO:K00274] [EC:1.4.3.4]
123637745  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
123641045  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
123641682  [KO:K01611] [EC:4.1.1.50]
123642850  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
123643282  [KO:K00274] [EC:1.4.3.4]
123644026  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
123644903  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
123645957  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
123647518  NOS3; nitric oxide synthase, endothelial [KO:K13242] [EC:1.14.13.39]
123647521  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
123647643  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
123648067  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
123648287  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
123648487  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
123648852  [KO:K00274] [EC:1.4.3.4]
123649821  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
123650153  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
123650168  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
123650255  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
123650363  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
123650578  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
123650712  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
123650894  SAT2; thialysine N-epsilon-acetyltransferase isoform X1 [KO:K00657] [EC:2.3.1.57]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
lcat00020  Citrate cycle (TCA cycle)
lcat00220  Arginine biosynthesis
lcat00250  Alanine, aspartate and glutamate metabolism
lcat00260  Glycine, serine and threonine metabolism
lcat00270  Cysteine and methionine metabolism
lcat00310  Lysine degradation
lcat00410  beta-Alanine metabolism
lcat00470  D-Amino acid metabolism
lcat00480  Glutathione metabolism
lcat00630  Glyoxylate and dicarboxylate metabolism
lcat00650  Butanoate metabolism
lcat00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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