KEGG   PATHWAY: leri00330
Entry
leri00330                   Pathway                                
Name
Arginine and proline metabolism - Leucoraja erinacea (little skate)
Class
Metabolism; Amino acid metabolism
Pathway map
leri00330  Arginine and proline metabolism
leri00330

Module
leri_M00015  Proline biosynthesis, glutamate => proline [PATH:leri00330]
leri_M00047  Creatine pathway [PATH:leri00330]
leri_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:leri00330]
leri_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:leri00330]
leri_M00970  Proline degradation, proline => glutamate [PATH:leri00330]
leri_M00972  Proline metabolism [PATH:leri00330]
Other DBs
GO: 0006525 0006560
Organism
Leucoraja erinacea (little skate) [GN:leri]
Gene
129712676  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
129711355  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
129713505  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
129713605  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
129700266  creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
129699702  creatine kinase M-type-like isoform X1 [KO:K27382] [EC:2.7.3.2]
129697086  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
129711593  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
129711650  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
129702768  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
129715448  amd1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
129696092  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
129703071  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
129709155  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
129713971  aldehyde dehydrogenase family 16 member A1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
129710558  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
129710561  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
129695789  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
129701198  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
129696656  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
129696749  cytosolic non-specific dipeptidase-like [KO:K08660] [EC:3.4.13.18]
129702792  sat1a.1; diamine acetyltransferase 1a.1 [KO:K00657] [EC:2.3.1.57]
129702194  amine oxidase [flavin-containing]-like [KO:K00274] [EC:1.4.3.4]
129702711  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
129711509  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
129709305  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
129710541  nos2b; nitric oxide synthase 2b, inducible [KO:K13241] [EC:1.14.13.39]
129694458  uncharacterized protein LOC129694458 [KO:K13242] [EC:1.14.13.39]
129700346  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
129703981  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
129705638  pycr3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
129708204  pycr1a; LOW QUALITY PROTEIN: pyrroline-5-carboxylate reductase 1a [KO:K00286] [EC:1.5.1.2]
129709458  proline dehydrogenase 1, mitochondrial-like isoform X1 [KO:K00318] [EC:1.5.5.2]
129711543  aldh4a1; LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
129704205  aldh18a1; LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
129699008  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
129701488  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
129712939  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
129697870  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
129713337  aspartate aminotransferase, cytoplasmic-like isoform X1 [KO:K14454] [EC:2.6.1.1]
129704132  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
129705244  got2a; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
129704161  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
129709175  D-amino-acid oxidase-like [KO:K00273] [EC:1.4.3.3]
129700216  trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
leri00020  Citrate cycle (TCA cycle)
leri00220  Arginine biosynthesis
leri00250  Alanine, aspartate and glutamate metabolism
leri00260  Glycine, serine and threonine metabolism
leri00270  Cysteine and methionine metabolism
leri00310  Lysine degradation
leri00410  beta-Alanine metabolism
leri00470  D-Amino acid metabolism
leri00480  Glutathione metabolism
leri00630  Glyoxylate and dicarboxylate metabolism
leri00650  Butanoate metabolism
leri00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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