KEGG   PATHWAY: mcep00330
Entry
mcep00330                   Pathway                                
Name
Arginine and proline metabolism - Mugil cephalus (flathead mullet)
Class
Metabolism; Amino acid metabolism
Pathway map
mcep00330  Arginine and proline metabolism
mcep00330

Module
mcep_M00015  Proline biosynthesis, glutamate => proline [PATH:mcep00330]
mcep_M00047  Creatine pathway [PATH:mcep00330]
mcep_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mcep00330]
mcep_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mcep00330]
mcep_M00970  Proline degradation, proline => glutamate [PATH:mcep00330]
mcep_M00972  Proline metabolism [PATH:mcep00330]
Other DBs
GO: 0006525 0006560
Organism
Mugil cephalus (flathead mullet) [GN:mcep]
Gene
124995390  [KO:K00657] [EC:2.3.1.57]
124995567  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
124996348  ckmt2a; creatine kinase, mitochondrial 2a (sarcomeric) isoform X1 [KO:K00933] [EC:2.7.3.2]
124996489  [KO:K00274] [EC:1.4.3.4]
124996880  [KO:K00318] [EC:1.5.5.2]
124997292  [KO:K00286] [EC:1.5.1.2]
124997597  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
124998130  [KO:K01581] [EC:4.1.1.17]
124998139  [KO:K01581] [EC:4.1.1.17]
124998832  [KO:K18384] [EC:4.2.1.77]
124998936  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
124999320  [KO:K00933] [EC:2.7.3.2]
125002077  [KO:K14454] [EC:2.6.1.1]
125002125  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
125003554  agmat; agmatinase, mitochondrial [KO:K27001]
125003565  [KO:K27382]
125004096  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
125004230  smoX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
125004590  pycr1b; pyrroline-5-carboxylate reductase 1b [KO:K00286] [EC:1.5.1.2]
125005420  [KO:K14455] [EC:2.6.1.1]
125005677  gatM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
125007247  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
125008990  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
125009774  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
125009861  pycr3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
125010011  gamT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
125010532  aldh9a1b; 4-trimethylaminobutyraldehyde dehydrogenase B [KO:K00149] [EC:1.2.1.47 1.2.1.3]
125012174  [KO:K00273] [EC:1.4.3.3]
125012213  [KO:K00933] [EC:2.7.3.2]
125012395  got1l1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
125012597  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
125012702  prodhb; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
125013166  ckmB; creatine kinase, muscle B [KO:K27382]
125013298  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
125013531  [KO:K00128] [EC:1.2.1.3]
125014106  [KO:K00128] [EC:1.2.1.3]
125014898  ckmt1; creatine kinase, mitochondrial 1 [KO:K00933] [EC:2.7.3.2]
125016696  [KO:K00128] [EC:1.2.1.3]
125017596  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
125018486  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
125018535  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b isoform X1 [KO:K00472] [EC:1.14.11.2]
125018580  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
125020538  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
125020850  ckmA; creatine kinase, muscle A [KO:K27382]
125020903  [KO:K00657] [EC:2.3.1.57]
125021348  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
125021453  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
125021607  [KO:K00128] [EC:1.2.1.3]
125021774  sat2b; diamine acetyltransferase 2b isoform X1 [KO:K00657] [EC:2.3.1.57]
125021986  aldh18a1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
125022109  [KO:K00657] [EC:2.3.1.57]
125022398  arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
125022425  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
125022564  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
125023305  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
125023654  ckbA; creatine kinase, brain a isoform X1 [KO:K00933] [EC:2.7.3.2]
125023753  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
125024411  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mcep00020  Citrate cycle (TCA cycle)
mcep00220  Arginine biosynthesis
mcep00250  Alanine, aspartate and glutamate metabolism
mcep00260  Glycine, serine and threonine metabolism
mcep00270  Cysteine and methionine metabolism
mcep00310  Lysine degradation
mcep00410  beta-Alanine metabolism
mcep00470  D-Amino acid metabolism
mcep00480  Glutathione metabolism
mcep00630  Glyoxylate and dicarboxylate metabolism
mcep00650  Butanoate metabolism
mcep00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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