KEGG   PATHWAY: mcf00330
Entry
mcf00330                    Pathway                                
Name
Arginine and proline metabolism - Macaca fascicularis (crab-eating macaque)
Class
Metabolism; Amino acid metabolism
Pathway map
mcf00330  Arginine and proline metabolism
mcf00330

Module
mcf_M00015  Proline biosynthesis, glutamate => proline [PATH:mcf00330]
mcf_M00047  Creatine pathway [PATH:mcf00330]
mcf_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mcf00330]
mcf_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mcf00330]
mcf_M00970  Proline degradation, proline => glutamate [PATH:mcf00330]
mcf_M00972  Proline metabolism [PATH:mcf00330]
Other DBs
GO: 0006525 0006560
Organism
Macaca fascicularis (crab-eating macaque) [GN:mcf]
Gene
101864777  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X2 [KO:K00286] [EC:1.5.1.2]
101865174  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
101865394  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
101865666  GOT1; aspartate aminotransferase, cytoplasmic isoform X1 [KO:K14454] [EC:2.6.1.1]
101866868  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
101867025  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
101867246  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
101925100  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
101925842  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X2 [KO:K00472] [EC:1.14.11.2]
101926607  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
101926835  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
102115940  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
102116569  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
102119382  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
102119447  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
102120326  GAMT; guanidinoacetate N-methyltransferase isoform X2 [KO:K00542] [EC:2.1.1.2]
102120771  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
102121432  [KO:K13241] [EC:1.14.13.39]
102121556  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
102122135  ALDH2; aldehyde dehydrogenase, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
102123521  NOS1; nitric oxide synthase 1 isoform X2 [KO:K13240] [EC:1.14.13.39]
102126199  AGMAT; guanidino acid hydrolase, mitochondrial isoform X1 [KO:K27001]
102126470  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
102126728  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
102129512  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
102131075  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
102131452  CNDP1; beta-Ala-His dipeptidase isoform X1 [KO:K05604] [EC:3.4.13.20]
102131487  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
102133980  ALDH1B1; aldehyde dehydrogenase X, mitochondrial isoform X2 [KO:K00128] [EC:1.2.1.3]
102135237  SAT2; thialysine N-epsilon-acetyltransferase [KO:K00657] [EC:2.3.1.57]
102138299  GATM; glycine amidinotransferase, mitochondrial isoform X1 [KO:K00613] [EC:2.1.4.1]
102138587  PRODH; proline dehydrogenase 1, mitochondrial isoform X2 [KO:K00318] [EC:1.5.5.2]
102138923  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
102139114  SMS; spermine synthase isoform X2 [KO:K00802] [EC:2.5.1.22]
102139794  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
102140146  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
102141093  [KO:K01581] [EC:4.1.1.17]
102141364  AZIN2; antizyme inhibitor 2 isoform X3 [KO:K01583] [EC:4.1.1.19]
102141466  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
102141942  AOC1; diamine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
102142294  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
102142383  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
102142672  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
102143087  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
102143504  NOS3; nitric oxide synthase 3 isoform X1 [KO:K13242] [EC:1.14.13.39]
102146019  CKM; creatine kinase M-type [KO:K27382]
102146162  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
102146166  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
102146328  [KO:K00286] [EC:1.5.1.2]
102146667  MAOA; amine oxidase [flavin-containing] A isoform X1 [KO:K00274] [EC:1.4.3.4]
123574668  [KO:K00933] [EC:2.7.3.2]
135967611  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mcf00020  Citrate cycle (TCA cycle)
mcf00220  Arginine biosynthesis
mcf00250  Alanine, aspartate and glutamate metabolism
mcf00260  Glycine, serine and threonine metabolism
mcf00270  Cysteine and methionine metabolism
mcf00310  Lysine degradation
mcf00410  beta-Alanine metabolism
mcf00470  D-Amino acid metabolism
mcf00480  Glutathione metabolism
mcf00630  Glyoxylate and dicarboxylate metabolism
mcf00650  Butanoate metabolism
mcf00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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