KEGG   PATHWAY: mhan00230
Entry
mhan00230                   Pathway                                
Name
Purine metabolism - Mixta hanseatica
Class
Metabolism; Nucleotide metabolism
Pathway map
mhan00230  Purine metabolism
mhan00230

Module
mhan_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mhan00230]
mhan_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mhan00230]
mhan_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mhan00230]
mhan_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mhan00230]
mhan_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mhan00230]
mhan_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mhan00230]
mhan_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mhan00230]
Other DBs
GO: 0006163 0042278
Organism
Mixta hanseatica [GN:mhan]
Gene
K6958_17400  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
K6958_01685  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
K6958_03550  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
K6958_06765  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
K6958_09490  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
K6958_14110  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
K6958_18705  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
K6958_14935  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
K6958_11910  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
K6958_15260  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
K6958_14930  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
K6958_06190  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
K6958_06195  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
K6958_14865  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
K6958_08810  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
K6958_18700  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
K6958_06075  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
K6958_06120  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
K6958_16270  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
K6958_01675  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
K6958_06110  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
K6958_03555  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
K6958_05705  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
K6958_16090  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K6958_17590  polyphenol oxidase family protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K6958_04225  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
K6958_15030  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
K6958_15125  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
K6958_03615  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
K6958_05515  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
K6958_16995  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
K6958_04835  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
K6958_10345  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
K6958_10350  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
K6958_12805  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
K6958_12800  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
K6958_12795  (2Fe-2S)-binding protein [KO:K13483]
K6958_09400  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
K6958_15025  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
K6958_04030  GMP reductase [KO:K00364] [EC:1.7.1.7]
K6958_10340  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
K6958_19895  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
K6958_13835  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
K6958_15960  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
K6958_13840  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K6958_15965  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K6958_02750  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
K6958_04370  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
K6958_13995  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
K6958_19905  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
K6958_14960  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K6958_19265  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K6958_16380  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
K6958_19145  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
K6958_17950  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
K6958_10230  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
K6958_12810  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
K6958_16460  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
K6958_17875  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
K6958_06100  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
K6958_16375  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
K6958_17390  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
K6958_03785  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
K6958_16300  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
K6958_16305  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
K6958_16310  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
K6958_10370  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
K6958_04735  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
K6958_11020  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
K6958_04730  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
K6958_04665  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
K6958_04670  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
K6958_04725  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
K6958_04720  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
K6958_04680  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
K6958_04690  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
K6958_05365  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mhan00030  Pentose phosphate pathway
mhan00220  Arginine biosynthesis
mhan00250  Alanine, aspartate and glutamate metabolism
mhan00260  Glycine, serine and threonine metabolism
mhan00340  Histidine metabolism
mhan00630  Glyoxylate and dicarboxylate metabolism
mhan00730  Thiamine metabolism
mhan00740  Riboflavin metabolism
mhan00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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