KEGG   PATHWAY: mun00564
Entry
mun00564                    Pathway                                
Name
Glycerophospholipid metabolism - Meriones unguiculatus (Mongolian gerbil)
Class
Metabolism; Lipid metabolism
Pathway map
mun00564  Glycerophospholipid metabolism
mun00564

Module
mun_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:mun00564]
mun_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:mun00564]
mun_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:mun00564]
Other DBs
GO: 0006650
Organism
Meriones unguiculatus (Mongolian gerbil) [GN:mun]
Gene
110547914  Gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
110547422  Gpd1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
110565712  glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
110557163  Gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
110541674  Gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
110560925  Gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
110547329  Gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
110560080  Gpat3; glycerol-3-phosphate acyltransferase 3 isoform X1 [KO:K13506] [EC:2.3.1.15]
110550853  Agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
110565390  Agpat1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
110556089  Agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
110554856  Agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X2 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
110559348  Agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
110553672  Lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
110563093  Mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
110564279  Mboat2; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
110555322  Gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
110552777  Adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
110556364  Plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
110551382  Plpp2; phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
110558764  Plpp1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
110552797  Lpin3; phosphatidate phosphatase LPIN3 isoform X1 [KO:K15728] [EC:3.1.3.4]
110541588  Lpin1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
110558713  Lpin2; phosphatidate phosphatase LPIN2 isoform X2 [KO:K15728] [EC:3.1.3.4]
110563305  Plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
110559831  Plpp4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
110549235  Dgki; diacylglycerol kinase iota isoform X8 [KO:K00901] [EC:2.7.1.107]
110549869  Dgkz; diacylglycerol kinase zeta isoform X3 [KO:K00901] [EC:2.7.1.107]
110552947  Dgkd; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
110548112  Dgkg; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
110555549  Dgke; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
110557436  Dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
110561256  Dgkh; diacylglycerol kinase eta isoform X5 [KO:K00901] [EC:2.7.1.107]
110541921  Dgkk; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
110559400  Dgka; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
110560058  Dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
110550296  Chpt1; cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
110550756  Cept1; choline/ethanolaminephosphotransferase 1 isoform X2 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
110553679  Pld1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
110557322  Pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
110556733  Pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
110558962  Pld4; 5'-3' exonuclease PLD4 isoform X2 [KO:K16860] [EC:3.1.4.4]
110545854  Lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
110545600  Pla2g1b; phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
110553222  Pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
110544978  Pla2g2c; putative inactive group IIC secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
110544979  Pla2g2f; group IIF secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
110544980  Pla2g2d; group IID secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
110544988  Pla2g2a; phospholipase A2, membrane associated isoform X3 [KO:K01047] [EC:3.1.1.4]
110544989  Pla2g5; phospholipase A2 group V [KO:K01047] [EC:3.1.1.4]
110556844  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
110557689  Pla2g3; group 3 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
110566324  Pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
110544984  Pla2g2e; group IIE secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
110553491  Pla2g4a; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
110554759  Pla2g4e; cytosolic phospholipase A2 epsilon isoform X2 [KO:K16342] [EC:3.1.1.4]
110554765  Pla2g4d; LOW QUALITY PROTEIN: cytosolic phospholipase A2 delta [KO:K16342] [EC:3.1.1.4]
110554773  Pla2g4f; cytosolic phospholipase A2 zeta isoform X1 [KO:K16342] [EC:3.1.1.4]
110554755  Pla2g4b; cytosolic phospholipase A2 beta isoform X2 [KO:K16342] [EC:3.1.1.4]
110566433  Pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
110554523  Plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
110551614  phospholipase A and acyltransferase 3 isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
110545378  Lpcat1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
110549066  lysophosphatidylcholine acyltransferase 2B-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
110545177  Lpcat2; lysophosphatidylcholine acyltransferase 2 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
110555490  Lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
110548605  Lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
110541034  Lypla1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
110545907  Pla2g15; phospholipase A2 group XV isoform X1 [KO:K06129] [EC:3.1.1.5]
110545424  Lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
110557014  Pnpla7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
132650561  Pnpla6; LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 6 [KO:K14676] [EC:3.1.1.5]
110557046  Gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X2 [KO:K18695] [EC:3.1.4.2]
110561617  Chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
110540909  Ache; acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
110549671  Chkb; choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
110547103  Chka; choline kinase alpha isoform X2 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
110551190  Phospho1; phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
110547656  Pcyt1a; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
110564185  Pcyt1b; choline-phosphate cytidylyltransferase B isoform X2 [KO:K00968] [EC:2.7.7.15]
110547708  Selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
110546734  Etnk2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
110559107  Etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
110548827  Pcyt2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
110553305  Etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
110550005  Pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
110557036  Cds2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
110554350  Cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
110555393  Pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
110561770  Ptdss1; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
110553910  Ptdss2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
110557545  Pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
110550286  Pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
110557099  Crls1; cardiolipin synthase (CMP-forming) isoform X1 [KO:K08744] [EC:2.7.8.41]
110562541  Tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
110561908  Lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
110548018  Cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
110555997  Mboat7; lysophospholipid acyltransferase 7 isoform X1 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
mun00010  Glycolysis / Gluconeogenesis
mun00260  Glycine, serine and threonine metabolism
mun00561  Glycerolipid metabolism
mun00562  Inositol phosphate metabolism
mun00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
mun00565  Ether lipid metabolism
mun00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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