KEGG   PATHWAY: myd00564
Entry
myd00564                    Pathway                                
Name
Glycerophospholipid metabolism - Myotis davidii (David's myotis)
Class
Metabolism; Lipid metabolism
Pathway map
myd00564  Glycerophospholipid metabolism
myd00564

Module
myd_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:myd00564]
myd_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:myd00564]
myd_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:myd00564]
Other DBs
GO: 0006650
Organism
Myotis davidii (David's myotis) [GN:myd]
Gene
102751492  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
102751569  PNPLA6; patatin like phospholipase domain containing 6 [KO:K14676] [EC:3.1.1.5]
102751623  PLB1; phospholipase B1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
102751920  [KO:K01047] [EC:3.1.1.4]
102751980  PLPP1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
102752015  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
102752662  PLA2G3; phospholipase A2 group III [KO:K01047] [EC:3.1.1.4]
102752720  [KO:K18695] [EC:3.1.4.2]
102752902  SGMS1; sphingomyelin synthase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
102752943  LPIN2; lipin 2 [KO:K15728] [EC:3.1.3.4]
102753150  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
102753196  GNPAT; glyceronephosphate O-acyltransferase [KO:K00649] [EC:2.3.1.42]
102753616  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102753885  PLA2G2A; phospholipase A2 group IIA [KO:K01047] [EC:3.1.1.4]
102754070  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
102754320  PLA2G4D; phospholipase A2 group IVD [KO:K16342] [EC:3.1.1.4]
102754370  PCYT1A; phosphate cytidylyltransferase 1, choline, alpha [KO:K00968] [EC:2.7.7.15]
102754480  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
102754521  PISD; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
102754611  PLA2G4E; phospholipase A2 group IVE [KO:K16342] [EC:3.1.1.4]
102754643  PLA2G12A; phospholipase A2 group XIIA [KO:K01047] [EC:3.1.1.4]
102754955  GPD1; glycerol-3-phosphate dehydrogenase 1 [KO:K00006] [EC:1.1.1.8]
102755016  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102755432  LPCAT3; lysophosphatidylcholine acyltransferase 3 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
102755578  CHPT1; choline phosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
102755717  PNPLA7; patatin like phospholipase domain containing 7 [KO:K14676] [EC:3.1.1.5]
102756009  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
102756028  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
102756358  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
102756653  AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
102756786  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102756796  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102756961  LPIN3; lipin 3 [KO:K15728] [EC:3.1.3.4]
102757081  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102757406  PLD3; phospholipase D family member 3 [KO:K16860] [EC:3.1.4.4]
102757439  LYPLA1; lysophospholipase I [KO:K06128] [EC:3.1.1.5]
102757678  AGPAT4; 1-acylglycerol-3-phosphate O-acyltransferase 4 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
102757823  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
102758294  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
102758376  PLPP2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
102758484  PLA2G1B; phospholipase A2 group IB [KO:K01047] [EC:3.1.1.4]
102759013  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
102759178  PLA2G10; phospholipase A2 group X [KO:K01047] [EC:3.1.1.4]
102759473  ACHE; acetylcholinesterase (Cartwright blood group) [KO:K01049] [EC:3.1.1.7]
102759634  AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2 [KO:K13509] [EC:2.3.1.51]
102760085  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
102760842  PLPP5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
102761235  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
102761259  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
102761633  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
102761765  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
102761815  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
102762232  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102762251  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
102763200  MBOAT7; membrane bound O-acyltransferase domain containing 7 [KO:K13516] [EC:2.3.1.-]
102763469  PLA2G6; phospholipase A2 group VI [KO:K16343] [EC:3.1.1.4]
102763884  CEPT1; choline/ethanolamine phosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
102764665  PLA2G15; phospholipase A2 group XV [KO:K06129] [EC:3.1.1.5]
102764739  LPIN1; lipin 1 [KO:K15728] [EC:3.1.3.4]
102765716  LPGAT1; lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
102766825  MBOAT2; membrane bound O-acyltransferase domain containing 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
102766895  LPCAT4; lysophosphatidylcholine acyltransferase 4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
102766964  PGS1; phosphatidylglycerophosphate synthase 1 [KO:K00995] [EC:2.7.8.5]
102767052  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
102767293  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
102767459  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102767701  LCAT; lecithin-cholesterol acyltransferase [KO:K00650] [EC:2.3.1.43]
102767845  CDS2; CDP-diacylglycerol synthase 2 [KO:K00981] [EC:2.7.7.41]
102767846  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
102768123  GPCPD1; glycerophosphocholine phosphodiesterase 1 [KO:K18695] [EC:3.1.4.2]
102768327  GPD1L; glycerol-3-phosphate dehydrogenase 1-like [KO:K00006] [EC:1.1.1.8]
102768385  AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 [KO:K13509] [EC:2.3.1.51]
102768950  PCYT2; phosphate cytidylyltransferase 2, ethanolamine [KO:K00967] [EC:2.7.7.14]
102769086  [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
102769327  PLA2G2E; phospholipase A2 group IIE [KO:K01047] [EC:3.1.1.4]
102770109  GPD2; glycerol-3-phosphate dehydrogenase 2 [KO:K00111] [EC:1.1.5.3]
102770762  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
102770806  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
102770982  GPAT3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
102771533  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102771591  AGPAT5; 1-acylglycerol-3-phosphate O-acyltransferase 5 [KO:K19007] [EC:2.3.1.51]
102771796  PLA2G4F; phospholipase A2 group IVF [KO:K16342] [EC:3.1.1.4]
102771993  SGMS2; sphingomyelin synthase 2 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
102772231  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
102772466  JMJD7; jumonji domain containing 7 [KO:K16342] [EC:3.1.1.4]
102772823  PLA2G2C; phospholipase A2 group IIC [KO:K01047] [EC:3.1.1.4]
102772989  PCYT1B; phosphate cytidylyltransferase 1, choline, beta [KO:K00968] [EC:2.7.7.15]
102773116  PLA2G2D; phospholipase A2 group IID [KO:K01047] [EC:3.1.1.4]
102773163  CDS1; CDP-diacylglycerol synthase 1 [KO:K00981] [EC:2.7.7.41]
102773170  CHKB; choline kinase beta [KO:K14156] [EC:2.7.1.32 2.7.1.82]
102773396  PLA2G5; phospholipase A2 group V [KO:K01047] [EC:3.1.1.4]
102773502  LYPLA2; lysophospholipase II [KO:K06130] [EC:3.1.1.5]
102773878  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
102773957  PLA2G2F; phospholipase A2 group IIF [KO:K01047] [EC:3.1.1.4]
102774257  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102774317  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
102774327  PLA2G4A; phospholipase A2 group IVA [KO:K16342] [EC:3.1.1.4]
102774453  MBOAT1; membrane bound O-acyltransferase domain containing 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
102774467  GPAM; glycerol-3-phosphate acyltransferase, mitochondrial [KO:K00629] [EC:2.3.1.15]
102774559  PLA2G12B; phospholipase A2 group XIIB [KO:K01047] [EC:3.1.1.4]
102774584  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
102774752  CRLS1; cardiolipin synthase 1 [KO:K08744] [EC:2.7.8.41]
102774873  SELENOI; selenoprotein I [KO:K00993] [EC:2.7.8.1]
102775093  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
102775293  TAZ; tafazzin [KO:K13511] [EC:2.3.1.-]
102775348  SAMD8; sterile alpha motif domain containing 8 [KO:K22697] [EC:3.1.4.62]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
myd00010  Glycolysis / Gluconeogenesis
myd00260  Glycine, serine and threonine metabolism
myd00561  Glycerolipid metabolism
myd00562  Inositol phosphate metabolism
myd00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
myd00565  Ether lipid metabolism
myd00620  Pyruvate metabolism
KO pathway
ko00564   

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