KEGG   PATHWAY: onl00330
Entry
onl00330                    Pathway                                
Name
Arginine and proline metabolism - Oreochromis niloticus (Nile tilapia)
Class
Metabolism; Amino acid metabolism
Pathway map
onl00330  Arginine and proline metabolism
onl00330

Module
onl_M00015  Proline biosynthesis, glutamate => proline [PATH:onl00330]
onl_M00047  Creatine pathway [PATH:onl00330]
onl_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:onl00330]
onl_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:onl00330]
onl_M00970  Proline degradation, proline => glutamate [PATH:onl00330]
onl_M00972  Proline metabolism [PATH:onl00330]
Other DBs
GO: 0006525 0006560
Organism
Oreochromis niloticus (Nile tilapia) [GN:onl]
Gene
100534582  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
100534585  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
100689888  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
100690220  pycr3; pyrroline-5-carboxylate reductase 3 isoform X3 [KO:K00286] [EC:1.5.1.2]
100690946  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
100691210  [KO:K14454] [EC:2.6.1.1]
100691284  got1; aspartate aminotransferase, cytoplasmic isoform X2 [KO:K14454] [EC:2.6.1.1]
100691341  oat; ornithine aminotransferase, mitochondrial isoform X1 [KO:K00819] [EC:2.6.1.13]
100692450  [KO:K00657] [EC:2.3.1.57]
100692799  [KO:K01581] [EC:4.1.1.17]
100693074  [KO:K01581] [EC:4.1.1.17]
100693706  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
100693723  [KO:K00128] [EC:1.2.1.3]
100694054  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
100695172  [KO:K00657] [EC:2.3.1.57]
100695866  [KO:K00318] [EC:1.5.5.2]
100696187  ckb; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
100696543  [KO:K00472] [EC:1.14.11.2]
100696662  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
100697664  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
100697766  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
100697781  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
100697817  [KO:K00318] [EC:1.5.5.2]
100698333  [KO:K00657] [EC:2.3.1.57]
100698670  [KO:K00128] [EC:1.2.1.3]
100698694  [KO:K27382]
100699093  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
100699354  [KO:K00933] [EC:2.7.3.2]
100699951  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
100700368  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
100700516  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
100701200  [KO:K00286] [EC:1.5.1.2]
100701380  [KO:K27382]
100702018  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
100702773  p4ha1; prolyl 4-hydroxylase subunit alpha-1 [KO:K00472] [EC:1.14.11.2]
100702938  [KO:K27382]
100703097  [KO:K14454] [EC:2.6.1.1]
100703463  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
100703669  prodh2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
100703740  [KO:K00286] [EC:1.5.1.2]
100703906  [KO:K00933] [EC:2.7.3.2]
100705401  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
100705651  agmat; agmatinase, mitochondrial [KO:K27001]
100705854  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
100706419  [KO:K00933] [EC:2.7.3.2]
100706482  [KO:K01476] [EC:3.5.3.1]
100706625  [KO:K00274] [EC:1.4.3.4]
100706906  got2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
100707184  aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
100707441  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
100707832  dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
100708530  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
100708726  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
100709269  [KO:K00933] [EC:2.7.3.2]
100709878  [KO:K00657] [EC:2.3.1.57]
100710353  [KO:K00657] [EC:2.3.1.57]
100711117  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X3 [KO:K00472] [EC:1.14.11.2]
100711126  l3hypdh; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
100711847  [KO:K00274] [EC:1.4.3.4]
102077099  [KO:K00274] [EC:1.4.3.4]
102078289  [KO:K00128] [EC:1.2.1.3]
102082725  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
109194280  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
109196322  [KO:K08660] [EC:3.4.13.18]
109196637  [KO:K08660] [EC:3.4.13.18]
109196929  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
109197600  [KO:K00274] [EC:1.4.3.4]
112841625  [KO:K00657] [EC:2.3.1.57]
112845256  [KO:K00657] [EC:2.3.1.57]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
onl00020  Citrate cycle (TCA cycle)
onl00220  Arginine biosynthesis
onl00250  Alanine, aspartate and glutamate metabolism
onl00260  Glycine, serine and threonine metabolism
onl00270  Cysteine and methionine metabolism
onl00310  Lysine degradation
onl00410  beta-Alanine metabolism
onl00470  D-Amino acid metabolism
onl00480  Glutathione metabolism
onl00630  Glyoxylate and dicarboxylate metabolism
onl00650  Butanoate metabolism
onl00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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