KEGG   PATHWAY: onl00250
Entry
onl00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Oreochromis niloticus (Nile tilapia)
Class
Metabolism; Amino acid metabolism
Pathway map
onl00250  Alanine, aspartate and glutamate metabolism
onl00250

Module
onl_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:onl00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Oreochromis niloticus (Nile tilapia) [GN:onl]
Gene
100534445  glula; glutamate-ammonia ligase (glutamine synthase) a [KO:K01915] [EC:6.3.1.2]
100690242  [KO:K00814] [EC:2.6.1.2]
100690674  [KO:K00820] [EC:2.6.1.16]
100691210  [KO:K14454] [EC:2.6.1.1]
100691284  got1; aspartate aminotransferase, cytoplasmic isoform X2 [KO:K14454] [EC:2.6.1.1]
100691320  [KO:K01939] [EC:6.3.4.4]
100692652  [KO:K00820] [EC:2.6.1.16]
100693080  nat8l; N-acetylaspartate synthetase [KO:K18309] [EC:2.3.1.17]
100693316  asns; asparagine synthetase [glutamine-hydrolyzing] isoform X2 [KO:K01953] [EC:6.3.5.4]
100694977  [KO:K01425] [EC:3.5.1.2]
100695178  [KO:K00139] [EC:1.2.1.24]
100695605  [KO:K03334] [EC:1.4.3.2]
100695998  [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
100696002  cps1; carbamoyl-phosphate synthase [ammonia], mitochondrial [KO:K01948] [EC:6.3.4.16]
100696276  [KO:K18309] [EC:2.3.1.17]
100697201  [KO:K03334] [EC:1.4.3.2]
100697237  ddo; D-aspartate oxidase [KO:K00272] [EC:1.4.3.1]
100698403  asl; argininosuccinate lyase [KO:K01755] [EC:4.3.2.1]
100698450  abat; 4-aminobutyrate aminotransferase, mitochondrial isoform X2 [KO:K13524] [EC:2.6.1.19 2.6.1.22]
100698845  [KO:K18310] [EC:6.3.1.17 6.3.2.41]
100700186  [KO:K01915] [EC:6.3.1.2]
100700233  cad; LOW QUALITY PROTEIN: CAD protein [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
100700257  gad2; glutamate decarboxylase 2 isoform X1 [KO:K01580] [EC:4.1.1.15]
100700516  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
100700633  [KO:K01756] [EC:4.3.2.2]
100701207  asrgl1; isoaspartyl peptidase/L-asparaginase [KO:K13051] [EC:3.5.1.1 3.4.19.5]
100701548  ass1; argininosuccinate synthase [KO:K01940] [EC:6.3.4.5]
100701752  [KO:K00827] [EC:2.6.1.44 2.6.1.40]
100702026  [KO:K00827] [EC:2.6.1.44 2.6.1.40]
100703044  [KO:K03334] [EC:1.4.3.2]
100703097  [KO:K14454] [EC:2.6.1.1]
100703315  [KO:K03334] [EC:1.4.3.2]
100703347  gad1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
100703760  glud1; glutamate dehydrogenase 1, mitochondrial [KO:K00261] [EC:1.4.1.3]
100703768  [KO:K00814] [EC:2.6.1.2]
100704451  [KO:K01580] [EC:4.1.1.15]
100704850  [KO:K01425] [EC:3.5.1.2]
100706371  [KO:K01756] [EC:4.3.2.2]
100706550  [KO:K01425] [EC:3.5.1.2]
100706566  aspa; aspartoacylase [KO:K01437] [EC:3.5.1.15]
100706639  [KO:K01756] [EC:4.3.2.2]
100706906  got2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
100707770  [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
100707943  [KO:K03334] [EC:1.4.3.2]
100707972  [KO:K00261] [EC:1.4.1.3]
100708086  adssl1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
100708095  [KO:K01939] [EC:6.3.4.4]
100709044  [KO:K13051] [EC:3.5.1.1 3.4.19.5]
100709457  nit2; omega-amidase NIT2 [KO:K13566] [EC:3.5.1.3]
100709690  gpt; alanine aminotransferase 1 isoform X2 [KO:K00814] [EC:2.6.1.2]
100710557  [KO:K01915] [EC:6.3.1.2]
100710799  [KO:K00814] [EC:2.6.1.2]
100711430  [KO:K01425] [EC:3.5.1.2]
100712052  [KO:K01580] [EC:4.1.1.15]
100712173  ppat; amidophosphoribosyltransferase isoform X2 [KO:K00764] [EC:2.4.2.14]
102082087  [KO:K00814] [EC:2.6.1.2]
102082621  [KO:K00139] [EC:1.2.1.24]
109194363  [KO:K01756] [EC:4.3.2.2]
109204270  [KO:K00139] [EC:1.2.1.24]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
onl00010  Glycolysis / Gluconeogenesis
onl00020  Citrate cycle (TCA cycle)
onl00220  Arginine biosynthesis
onl00230  Purine metabolism
onl00240  Pyrimidine metabolism
onl00260  Glycine, serine and threonine metabolism
onl00330  Arginine and proline metabolism
onl00340  Histidine metabolism
onl00410  beta-Alanine metabolism
onl00470  D-Amino acid metabolism
onl00480  Glutathione metabolism
onl00520  Amino sugar and nucleotide sugar metabolism
onl00620  Pyruvate metabolism
onl00630  Glyoxylate and dicarboxylate metabolism
onl00650  Butanoate metabolism
onl00760  Nicotinate and nicotinamide metabolism
onl00770  Pantothenate and CoA biosynthesis
onl00860  Porphyrin metabolism
onl00910  Nitrogen metabolism
KO pathway
ko00250   

DBGET integrated database retrieval system