KEGG   PATHWAY: blr00230
Entry
blr00230                    Pathway                                
Name
Purine metabolism - Brevibacillus laterosporus
Class
Metabolism; Nucleotide metabolism
Pathway map
blr00230  Purine metabolism
blr00230

Module
blr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:blr00230]
blr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:blr00230]
blr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:blr00230]
blr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:blr00230]
blr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:blr00230]
Other DBs
GO: 0006163 0042278
Organism
Brevibacillus laterosporus [GN:blr]
Gene
BRLA_c017340  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BRLA_c017390  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BRLA_c000730  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BRLA_c004860  amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
BRLA_c004950  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BRLA_c004880  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BRLA_c008300  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BRLA_c004850  phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
BRLA_c004830  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
BRLA_c004840  phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BRLA_c004870  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BRLA_c004780  N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BRLA_c004770  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BRLA_c004820  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BRLA_c004790  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BRLA_c004940  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BRLA_c012910  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BRLA_c046140  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BRLA_c008210  yfkN_1; trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
BRLA_c037680  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BRLA_c026070  purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
BRLA_c017400  purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
BRLA_c027370  purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
BRLA_c034760  laccase domain protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BRLA_c000930  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BRLA_c000270  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BRLA_c019160  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BRLA_c038730  Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
BRLA_c012110  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BRLA_c012720  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
BRLA_c004750  GMP synthase [KO:K01951] [EC:6.3.5.2]
BRLA_c022730  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BRLA_c034240  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BRLA_c016050  nrdZ; ribonucleoside-diphosphate reductase NrdZ [KO:K00525] [EC:1.17.4.1]
BRLA_c024310  ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
BRLA_c024300  ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BRLA_c018100  ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BRLA_c002870  anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BRLA_c014720  deoxyguanosine kinase [KO:K15518] [EC:2.7.1.113]
BRLA_c012920  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BRLA_c039860  yjbM_2; GTP pyrophosphokinase YjbM [KO:K07816] [EC:2.7.6.5]
BRLA_c021810  yjbM_1; GTP pyrophosphokinase YjbM [KO:K07816] [EC:2.7.6.5]
BRLA_c033810  ywaC; GTP pyrophosphokinase YwaC [KO:K07816] [EC:2.7.6.5]
BRLA_c046370  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BRLA_c014730  deoxyadenosine/deoxycytidine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
BRLA_c004970  yerA; putative adenine deaminase YerA [KO:K01486] [EC:3.5.4.2]
BRLA_c039890  adenine deaminase [KO:K01486] [EC:3.5.4.2]
BRLA_c045500  yfkN_2; trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BRLA_c012700  2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BRLA_c032120  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
BRLA_c002000  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BRLA_c006270  putative adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BRLA_c010920  sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BRLA_c024370  N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
BRLA_c022430  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
BRLA_c022450  putative allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
BRLA_c022460  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
BRLA_c022470  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
BRLA_c022510  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
blr00030  Pentose phosphate pathway
blr00220  Arginine biosynthesis
blr00250  Alanine, aspartate and glutamate metabolism
blr00260  Glycine, serine and threonine metabolism
blr00340  Histidine metabolism
blr00630  Glyoxylate and dicarboxylate metabolism
blr00730  Thiamine metabolism
blr00740  Riboflavin metabolism
blr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system