KEGG   PATHWAY: ccup00230
Entry
ccup00230                   Pathway                                
Name
Purine metabolism - Cupriavidus sp. USMAHM13
Class
Metabolism; Nucleotide metabolism
Pathway map
ccup00230  Purine metabolism
ccup00230

Module
ccup_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ccup00230]
ccup_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ccup00230]
ccup_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ccup00230]
ccup_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ccup00230]
ccup_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ccup00230]
ccup_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ccup00230]
ccup_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ccup00230]
Other DBs
GO: 0006163 0042278
Organism
Cupriavidus sp. USMAHM13 [GN:ccup]
Gene
BKK81_08010  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BKK81_06250  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BKK81_15960  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BKK81_04235  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BKK81_14815  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BKK81_07315  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BKK81_16625  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BKK81_19005  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BKK81_11350  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BKK81_16780  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BKK81_05495  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BKK81_05490  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BKK81_05485  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BKK81_17010  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BKK81_04875  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BKK81_04350  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BKK81_25215  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
BKK81_23180  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
BKK81_13905  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BKK81_16730  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
BKK81_12660  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BKK81_17400  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BKK81_09860  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
BKK81_13865  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BKK81_07505  non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BKK81_07780  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BKK81_07775  xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BKK81_22785  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
BKK81_09870  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
BKK81_07760  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BKK81_07530  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BKK81_13985  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BKK81_17365  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BKK81_17345  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BKK81_00215  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BKK81_07540  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BKK81_14130  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BKK81_13130  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
BKK81_12205  hypothetical protein [KO:K07816] [EC:2.7.6.5]
BKK81_13790  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BKK81_11600  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BKK81_17280  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
BKK81_21500  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BKK81_07765  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BKK81_05875  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BKK81_05680  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BKK81_27540  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
BKK81_23410  phosphorylase [KO:K00988] [EC:2.7.7.5 2.7.7.53]
BKK81_16075  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
BKK81_16400  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
BKK81_16405  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
BKK81_11110  monooxygenase [KO:K22879] [EC:1.14.13.113]
BKK81_10870  FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
BKK81_07735  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BKK81_07715  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BKK81_02750  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
BKK81_07720  allantoinase [KO:K16842] [EC:3.5.2.5]
BKK81_00985  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
BKK81_11635  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
BKK81_21945  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BKK81_08160  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BKK81_08155  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BKK81_08145  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BKK81_32215  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ccup00030  Pentose phosphate pathway
ccup00220  Arginine biosynthesis
ccup00250  Alanine, aspartate and glutamate metabolism
ccup00260  Glycine, serine and threonine metabolism
ccup00340  Histidine metabolism
ccup00630  Glyoxylate and dicarboxylate metabolism
ccup00730  Thiamine metabolism
ccup00740  Riboflavin metabolism
ccup00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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