KEGG   PATHWAY: csr00520
Entry
csr00520                    Pathway                                
Name
Amino sugar and nucleotide sugar metabolism - Clostridium saccharoperbutylacetonicum
Class
Metabolism; Carbohydrate metabolism
Pathway map
csr00520  Amino sugar and nucleotide sugar metabolism
csr00520

Module
csr_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:csr00520]
csr_M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:csr00520]
csr_M00909  UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:csr00520]
Other DBs
GO: 0006040 0009225
Organism
Clostridium saccharoperbutylacetonicum [GN:csr]
Gene
Cspa_c42550  PTS system, glucose subfamily, IIA subunit [KO:K02777] [EC:2.7.1.-]
Cspa_c50610  gamP; putative PTS system glucosamine-specific EIICBA component GamP [KO:K02777] [EC:2.7.1.-]
Cspa_c56510  PTS system IIA component, Glc family [KO:K02777] [EC:2.7.1.-]
Cspa_c17540  ptsG; PTS system glucose-specific EIICBA component PtsG [KO:K02777] [EC:2.7.1.-]
Cspa_c52650  nagA; N-acetylglucosamine-6-phosphate deacetylase NagA [KO:K01443] [EC:3.5.1.25]
Cspa_c48200  nagB; glucosamine-6-phosphate deaminase NagB [KO:K02564] [EC:3.5.99.6]
Cspa_c57840  sugar kinase, ribokinase family [KO:K00847] [EC:2.7.1.4]
Cspa_c56590  sugar kinase, ribokinase family [KO:K00847] [EC:2.7.1.4]
Cspa_c17550  sugar kinase, ribokinase family [KO:K00847] [EC:2.7.1.4]
Cspa_c02980  glmS1; glutamine--fructose-6-phosphate aminotransferase [KO:K00820] [EC:2.6.1.16]
Cspa_c21530  glmS2; glutamine--fructose-6-phosphate aminotransferase [KO:K00820] [EC:2.6.1.16]
Cspa_c02610  glmM; phosphoglucosamine mutase GlmM [KO:K03431] [EC:5.4.2.10]
Cspa_c01040  glmU; bifunctional protein GlmU [KO:K04042] [EC:2.7.7.23 2.3.1.157]
Cspa_c57980  murA2; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 [KO:K00790] [EC:2.5.1.7]
Cspa_c06290  murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 [KO:K00790] [EC:2.5.1.7]
Cspa_c55120  murB; UDP-N-acetylenolpyruvoylglucosamine reductase MurB [KO:K00075] [EC:1.3.1.98]
Cspa_c06170  wecB; UDP-N-acetylglucosamine 2-epimerase WecB [KO:K01791] [EC:5.1.3.14]
Cspa_c55370  wbpA2; UDP-N-acetyl-D-glucosamine 6-dehydrogenase WbpA [KO:K13015] [EC:1.1.1.136]
Cspa_c19780  wbpA1; UDP-N-acetyl-D-glucosamine 6-dehydrogenase WbpA [KO:K13015] [EC:1.1.1.136]
Cspa_c53470  putative dehydrogenase [KO:K13020] [EC:1.1.1.335]
Cspa_c55380  wbpD; UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase WbpD [KO:K13018] [EC:2.3.1.201]
Cspa_c53520  UDP-N-acetylglucosamine 2-epimerase [KO:K13019] [EC:5.1.3.23]
Cspa_c45680  pseB; UDP-N-acetylglucosamine 4,6-dehydratase PseD [KO:K15894] [EC:4.2.1.115 5.1.3.-]
Cspa_c45300  pseG; pseudaminic acid biosynthesis-associated protein PseG [KO:K15897] [EC:3.6.1.57]
Cspa_c45320  pseI; pseudaminic acid synthase PseI [KO:K15898] [EC:2.5.1.97]
Cspa_c42190  abfA; alpha-N-arabinofuranosidase AbfA [KO:K01209] [EC:3.2.1.55]
Cspa_c49220  alpha-L-arabinofuranosidase [KO:K01209] [EC:3.2.1.55]
Cspa_c48500  xsa1; alpha-N-arabinofuranosidase 2 [KO:K01209] [EC:3.2.1.55]
Cspa_c32780  xynD3; arabinoxylan arabinofuranohydrolase XynD [KO:K15921] [EC:3.2.1.55]
Cspa_c14970  xynD1; arabinoxylan arabinofuranohydrolase XynD [KO:K15921] [EC:3.2.1.55]
Cspa_c21080  xynD2; arabinoxylan arabinofuranohydrolase XynD [KO:K15921] [EC:3.2.1.55]
Cspa_c19750  rffG1; dTDP-glucose 4,6-dehydratase 2 [KO:K08678] [EC:4.1.1.35]
Cspa_c43100  xylB2; xylosidase/arabinosidase XylB [KO:K01198] [EC:3.2.1.37]
Cspa_c48600  xynB10; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c43030  xynB6; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c22400  xynB3; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c48540  xylB4; xylosidase/arabinosidase XylB [KO:K01198] [EC:3.2.1.37]
Cspa_c29940  xynB5; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c43160  xynB7; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c47900  xynB9; beta-xylosidase XynB [KO:K01198] [EC:3.2.1.37]
Cspa_c47240  glcB; PTS system glucoside-specific EIICBA component GlcB [KO:K20118] [EC:2.7.1.199]
Cspa_c52690  glcK3; glucokinase GlcK [KO:K25026] [EC:2.7.1.2]
Cspa_c40960  glcK1; glucokinase GlcK [KO:K25026] [EC:2.7.1.2]
Cspa_c43050  glcK2; glucokinase GlcK [KO:K25026] [EC:2.7.1.2]
Cspa_c55570  glcK4; glucokinase GlcK [KO:K25026] [EC:2.7.1.2]
Cspa_c10680  pgcA; phosphoglucomutase PgcA [KO:K01835] [EC:5.4.2.2]
Cspa_c53460  gtaB; UTP--glucose-1-phosphate uridylyltransferase GtaB [KO:K00963] [EC:2.7.7.9]
Cspa_c12190  galU; UTP-glucose-1-phosphate uridylyltransferase GalU [KO:K00963] [EC:2.7.7.9]
Cspa_c12030  UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
Cspa_c46540  galK; galactokinase GalK [KO:K00849] [EC:2.7.1.6]
Cspa_c46560  galT; galactose-1-phosphate uridylyltransferase GalT [KO:K00965] [EC:2.7.7.12]
Cspa_c40170  galE1; UDP-glucose 4-epimerase GalE [KO:K01784] [EC:5.1.3.2]
Cspa_c53510  galE3; UDP-glucose 4-epimerase GalE [KO:K01784] [EC:5.1.3.2]
Cspa_c46550  galE2; UDP-glucose 4-epimerase GalE [KO:K01784] [EC:5.1.3.2]
Cspa_c19760  nucleoside-diphosphate-sugar epimerase [KO:K01784] [EC:5.1.3.2]
Cspa_c54100  NAD-dependent epimerase/dehydratase [KO:K01784] [EC:5.1.3.2]
Cspa_c55910  PTS system D-mannose-specific IIA component, Man family [KO:K02793] [EC:2.7.1.191]
Cspa_c55900  PTS system, mannose/fructose/sorbose family, IIB component [KO:K02794] [EC:2.7.1.191]
Cspa_c48810  PTS system D-glucose-specific IIA component, Man family/PTS system D-glucose-specific IIB component, Man family [KO:K02794] [EC:2.7.1.191]
Cspa_c48800  PTS system D-glucose-specific IIC component, Man family [KO:K02795]
Cspa_c55890  PTS system, mannose/fructose/sorbose family, IIC component [KO:K02795]
Cspa_c48790  PTS system D-glucose-specific IID component, Man family [KO:K02796]
Cspa_c55880  PTS system, mannose/fructose/sorbose family, IID component [KO:K02796]
Cspa_c04520  pgi; glucose-6-phosphate isomerase Pgi [KO:K01810] [EC:5.3.1.9]
Cspa_c52710  pmi; mannose-6-phosphate isomerase Pmi [KO:K01809] [EC:5.3.1.8]
Cspa_c10820  gmuF; putative mannose-6-phosphate isomerase GmuF [KO:K01809] [EC:5.3.1.8]
Cspa_c45460  mannose-6-phosphate isomerase [KO:K01809] [EC:5.3.1.8]
Cspa_c04300  manC; mannose-1-phosphate guanylyltransferase ManC [KO:K00971] [EC:2.7.7.13]
Cspa_c03670  rfbA; putative mannose-1-phosphate guanylyltransferase RfbA [KO:K00971] [EC:2.7.7.13]
Cspa_c54150  rfbF; glucose-1-phosphate cytidylyltransferase RfbF [KO:K00978] [EC:2.7.7.33]
Cspa_c54140  rfbG; CDP-glucose 4,6-dehydratase RfbG [KO:K01709] [EC:4.2.1.45]
Cspa_c54130  rfbH; lipopolysaccharide biosynthesis protein RfbH [KO:K12452] [EC:1.17.1.1]
Cspa_c48240  glgD1; glycogen biosynthesis protein GlgD [KO:K00975] [EC:2.7.7.27]
Cspa_c48250  glgC1; glucose-1-phosphate adenylyltransferase GlgC [KO:K00975] [EC:2.7.7.27]
Cspa_c55780  glgD2; glycogen biosynthesis protein GlgD [KO:K00975] [EC:2.7.7.27]
Cspa_c55790  glgC2; glucose-1-phosphate adenylyltransferase GlgC [KO:K00975] [EC:2.7.7.27]
Compound
C00029  UDP-glucose
C00031  D-Glucose
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00052  UDP-alpha-D-galactose
C00085  D-Fructose 6-phosphate
C00095  D-Fructose
C00096  GDP-mannose
C00103  D-Glucose 1-phosphate
C00128  CMP-N-acetylneuraminate
C00140  N-Acetyl-D-glucosamine
C00159  D-Mannose
C00167  UDP-glucuronate
C00181  D-Xylose
C00190  UDP-D-xylose
C00191  D-Glucuronate
C00203  UDP-N-acetyl-D-galactosamine
C00216  D-Arabinose
C00259  L-Arabinose
C00267  alpha-D-Glucose
C00270  N-Acetylneuraminate
C00275  D-Mannose 6-phosphate
C00325  GDP-L-fucose
C00329  D-Glucosamine
C00333  D-Galacturonate
C00352  D-Glucosamine 6-phosphate
C00357  N-Acetyl-D-glucosamine 6-phosphate
C00394  GDP-glucose
C00446  alpha-D-Galactose 1-phosphate
C00461  Chitin
C00498  ADP-glucose
C00501  CDP-glucose
C00617  UDP-D-galacturonate
C00636  D-Mannose 1-phosphate
C00645  N-Acetyl-D-mannosamine
C00668  alpha-D-Glucose 6-phosphate
C00714  Pectin
C00734  Chitosan
C00935  UDP-L-arabinose
C00976  GDP-D-mannuronate
C00984  alpha-D-Galactose
C00996  Ferricytochrome b5
C00999  Ferrocytochrome b5
C01019  L-Fucose
C01050  UDP-N-acetylmuramate
C01132  N-Acetyl-D-galactosamine
C01170  UDP-N-acetyl-D-mannosamine
C01219  CDP-4-dehydro-6-deoxy-D-glucose
C01222  GDP-4-dehydro-6-deoxy-D-mannose
C01623  UDP-apiose
C01674  Chitobiose
C01788  CDP-abequose
C02199  UDP-L-rhamnose
C02280  GDP-L-galactose
C02352  1,4-beta-D-Xylan
C02474  Arabinan
C02713  N-Acetylmuramate
C02977  GDP-6-deoxy-D-talose
C02985  L-Fucose 1-phosphate
C03117  GDP-6-deoxy-D-mannose
C03410  N-Glycoloyl-neuraminate
C03598  CDP-3,6-dideoxy-D-glucose
C03599  CDP-3,6-dideoxy-D-mannose
C03691  CMP-N-glycoloylneuraminate
C03733  UDP-alpha-D-galactofuranose
C03906  beta-L-Arabinose 1-phosphate
C04037  1-Phospho-alpha-D-galacturonate
C04089  UDP-4-dehydro-6-deoxy-D-glucose
C04257  N-Acetyl-D-mannosamine 6-phosphate
C04297  CDP-4-dehydro-3,6-dideoxy-D-glucose
C04501  N-Acetyl-alpha-D-glucosamine 1-phosphate
C04573  UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate
C04613  UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose
C04630  UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose
C04631  UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
C05385  D-Glucuronate 1-phosphate
C06023  D-Glucosaminide
C06156  alpha-D-Glucosamine 1-phosphate
C06240  UDP-N-acetyl-D-mannosaminouronate
C06241  N-Acetylneuraminate 9-phosphate
C06377  D-Galactosamine 6-phosphate
C11521  UDP-6-sulfoquinovose
C13952  UDP-N-acetyl-D-galactosaminuronic acid
C15925  GDP-L-gulose
C16153  UDP-L-Ara4N
C16154  UDP-L-Ara4FN
C16155  UDP-L-Ara4O
C16156  Undecaprenyl phosphate alpha-L-Ara4FN
C16157  Undecaprenyl phosphate alpha-L-Ara4N
C16183  alpha-D-Arabinopyranose 1-phosphate
C16698  N-Acetylmuramic acid 6-phosphate
C17269  GDP-D-arabinopyranose
C17326  CDP-4-dehydro-3,6-dideoxy-D-glucose epimer
C17327  CDP-ascarylose
C17328  UDP-4-keto-rhamnose
C18060  N-Acetyl-alpha-D-galactosamine 1-phosphate
C18094  UDP-L-arabinofuranose
C19725  UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
C19745  UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
C19769  1,6-Anhydro-N-acetyl-beta-muramate
C19823  UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose
C19961  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine
C19971  UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose
C19972  2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose
C20082  Pseudaminic acid
C20083  CMP-pseudaminic acid
C20357  UDP-N,N'-diacetylbacillosamine
C20359  UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate
C20395  UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate
C20418  N,N'-Diacetyllegionaminate
C20419  CMP-N,N'-diacetyllegionaminate
C20424  2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose
C20638  GDP-4-amino-4,6-dideoxy-alpha-D-mannose
C20672  GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose
C20934  3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate
C21027  N-Acetylmuramic acid alpha-1-phosphate
C21383  3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate
C21384  CMP-3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate
C22029  alpha-D-Galactosamine 1-phosphate
C22938  UDP-N-acetyl-alpha-D-xylosamine
Reference
PMID:2793832
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
Reference
PMID:8071227
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
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J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Reference
PMID:8444803
  Authors
Kessler AC, Haase A, Reeves PR
  Title
Molecular analysis of the 3,6-dideoxyhexose pathway genes of Yersinia pseudotuberculosis serogroup IIA.
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J Bacteriol 175:1412-22 (1993)
DOI:10.1128/JB.175.5.1412-1422.1993
Reference
PMID:9811644
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  Title
Accumulation of the enterobacterial common antigen lipid II biosynthetic intermediate stimulates degP transcription in Escherichia coli.
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J Bacteriol 180:5875-84 (1998)
DOI:10.1128/JB.180.22.5875-5884.1998
Reference
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  Title
Characterization of the O-antigen gene clusters of Yersinia pseudotuberculosis and the cryptic O-antigen gene cluster of Yersinia pestis shows that the plague bacillus is most closely related to and has evolved from Y. pseudotuberculosis serotype O:1b.
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Mol Microbiol 37:316-30 (2000)
DOI:10.1046/j.1365-2958.2000.01993.x
Reference
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Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV
  Title
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
  Journal
Nature 406:959-64 (2000)
DOI:10.1038/35023079
Reference
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  Title
Redirection of sialic acid metabolism in genetically engineered Escherichia coli.
  Journal
Glycobiology 11:533-9 (2001)
DOI:10.1093/glycob/11.7.533
Reference
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  Title
In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance.
  Journal
J Bacteriol 185:1218-28 (2003)
DOI:10.1128/JB.185.4.1218-1228.2003
Reference
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JACOBSON B, DAVIDSON EA
  Title
Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5-epimerase.
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J Biol Chem 237:638-42 (1962)
Reference
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  Title
Nucleotide sugar interconversions and cell wall biosynthesis: how to bring the inside to the outside.
  Journal
Curr Opin Plant Biol 7:277-84 (2004)
DOI:10.1016/j.pbi.2004.03.004
Reference
  Authors
Uehara T, Park JT
  Title
The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling.
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J Bacteriol 186:7273-9 (2004)
DOI:10.1128/JB.186.21.7273-7279.2004
Reference
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  Title
A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose.
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J Biol Chem 280:14154-67 (2005)
DOI:10.1074/jbc.M414265200
Reference
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  Title
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.
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J Biol Chem 280:23000-8 (2005)
DOI:10.1074/jbc.M501534200
Reference
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  Title
Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase.
  Journal
Glycobiology 16:165-72 (2006)
DOI:10.1093/glycob/cwj050
Reference
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  Title
Large-scale approaches for glycobiology.
  Journal
Genome Biol 6:236 (2005)
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Reference
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Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT
  Title
MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall.
  Journal
J Bacteriol 188:1660-2 (2006)
DOI:10.1128/JB.188.4.1660-1662.2006
Reference
  Authors
Lanot A, Hodge D, Jackson RG, George GL, Elias L, Lim EK, Vaistij FE, Bowles DJ
  Title
The glucosyltransferase UGT72E2 is responsible for monolignol 4-O-glucoside production in Arabidopsis thaliana.
  Journal
Plant J 48:286-95 (2006)
DOI:10.1111/j.1365-313X.2006.02872.x
Reference
  Authors
Muller R, Morant M, Jarmer H, Nilsson L, Nielsen TH
  Title
Genome-wide analysis of the Arabidopsis leaf transcriptome reveals interaction of phosphate and sugar metabolism.
  Journal
Plant Physiol 143:156-71 (2007)
DOI:10.1104/pp.106.090167
Reference
  Authors
Oka T, Nemoto T, Jigami Y
  Title
Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion.
  Journal
J Biol Chem 282:5389-403 (2007)
DOI:10.1074/jbc.M610196200
Reference
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  Title
Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.
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J Bacteriol 189:8727-36 (2007)
DOI:10.1128/JB.00793-07
Reference
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Kotake T, Hojo S, Tajima N, Matsuoka K, Koyama T, Tsumuraya Y
  Title
A bifunctional enzyme with L-fucokinase and GDP-L-fucose pyrophosphorylase activities salvages free L-fucose in Arabidopsis.
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J Biol Chem 283:8125-35 (2008)
DOI:10.1074/jbc.M710078200
Reference
  Authors
Vorholter FJ, Schneiker S, Goesmann A, Krause L, Bekel T, Kaiser O, Linke B, Patschkowski T, Ruckert C, Schmid J, Sidhu VK, Sieber V, Tauch A, Watt SA, Weisshaar B, Becker A, Niehaus K, Puhler A.
  Title
The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis.
  Journal
J Biotechnol 134:33-45 (2008)
DOI:10.1016/j.jbiotec.2007.12.013
Reference
  Authors
Albermann C, Piepersberg W
  Title
Expression and identification of the RfbE protein from Vibrio cholerae O1 and its use for the enzymatic synthesis of GDP-D-perosamine.
  Journal
Glycobiology 11:655-61 (2001)
DOI:10.1093/glycob/11.8.655
Related
pathway
csr00010  Glycolysis / Gluconeogenesis
csr00040  Pentose and glucuronate interconversions
csr00051  Fructose and mannose metabolism
csr00052  Galactose metabolism
csr00053  Ascorbate and aldarate metabolism
csr00500  Starch and sucrose metabolism
csr00523  Polyketide sugar unit biosynthesis
csr00525  Acarbose and validamycin biosynthesis
csr00540  Lipopolysaccharide biosynthesis
csr00550  Peptidoglycan biosynthesis
KO pathway
ko00520   
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