KEGG   PATHWAY: ead00230
Entry
ead00230                    Pathway                                
Name
Purine metabolism - Ensifer adhaerens OV14
Class
Metabolism; Nucleotide metabolism
Pathway map
ead00230  Purine metabolism
ead00230

Module
ead_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ead00230]
ead_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ead00230]
ead_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ead00230]
ead_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ead00230]
ead_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ead00230]
ead_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ead00230]
Other DBs
GO: 0006163 0042278
Organism
Ensifer adhaerens OV14 [GN:ead]
Gene
OV14_0972  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
OV14_0351  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
OV14_3804  prsA; ribose-phosphate pyrophosphokinase, PrsA [KO:K00948] [EC:2.7.6.1]
OV14_3437  prsA; ribose-phosphate pyrophosphokinase, PrsA [KO:K00948] [EC:2.7.6.1]
OV14_2144  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
OV14_1791  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
OV14_2209  purN; putative 5'-phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
OV14_2952  purL; phosphoribosylformylglycinamidine synthase II (FGAMsynthase II) PurL [KO:K23269] [EC:6.3.5.3]
OV14_2947  purS; phosphoribosylformylglycinamidine synthase PurS [KO:K23264] [EC:6.3.5.3]
OV14_2949  purQ; phosphoribosylformylglycinamidine synthase I (FGAMsynthase I) PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
OV14_2210  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
OV14_0279  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
OV14_0278  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
OV14_2843  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC [KO:K01923] [EC:6.3.2.6]
OV14_2946  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC [KO:K01923] [EC:6.3.2.6]
OV14_2940  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
OV14_0854  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
OV14_3822  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
OV14_0300  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
OV14_2618  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
OV14_0967  deoD; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
OV14_3801  putative inner membrane protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
OV14_0115  putative hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
OV14_1689  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
OV14_2189  putative nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
OV14_1291  Ham1-like protein [KO:K01519] [EC:3.6.1.66]
OV14_2791  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
OV14_b0316  putative dehydrogenase [KO:K00087] [EC:1.17.1.4]
OV14_b0318  xanthine dehydrogenase [KO:K13479] [EC:1.17.1.4]
OV14_3898  xdhA; xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
OV14_a0412  xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
OV14_3899  xdhB; xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
OV14_a0413  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
OV14_0644  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
OV14_a0555  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
OV14_1203  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
OV14_1269  CMP/dCMP deaminase, zinc-binding [KO:K01487] [EC:3.5.4.3]
OV14_3903  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
OV14_a0419  guanine deaminase [KO:K01487] [EC:3.5.4.3]
OV14_2168  guanylate kinase [KO:K00942] [EC:2.7.4.8]
OV14_2893  nrd; ribonucleotide-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
OV14_2606  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
OV14_2120  putative hydrolase protein [KO:K06952] [EC:3.1.3.89]
OV14_2087  GTP pyrophosphohydrolase/synthetase, RelA/SpoT family [KO:K01139] [EC:2.7.6.5 3.1.7.2]
OV14_1684  putative Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
OV14_2214  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
OV14_b0908  cya3; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_3557  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_0516  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_0401  hypothetical protein [KO:K01768] [EC:4.6.1.1]
OV14_b0028  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_1642  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_3194  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_b1234  putative adenylate/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_3112  cyaD; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
OV14_3952  putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_b0328  putative membrane-bound adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_4008  cyaC; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_1391  putative adenylyl / guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_b1025  putative membrane-bound adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_0260  cyaF; adenylate cyclase 3 [KO:K01768] [EC:4.6.1.1]
OV14_3420  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_3421  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_a1849  cyaG; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_2457  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_1124  putative adenylate/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_a1537  putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
OV14_b0567  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_2220  adenylate cyclase 2 [KO:K01768] [EC:4.6.1.1]
OV14_a0343  adenylate cyclase-like protein [KO:K01768] [EC:4.6.1.1]
OV14_a1022  putative adenylate class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
OV14_0199  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
OV14_0971  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
OV14_2070  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
OV14_3882  adeC; adenine deaminase 1 [KO:K01486] [EC:3.5.4.2]
OV14_a0121  adeC; adenine deaminase 1 [KO:K01486] [EC:3.5.4.2]
OV14_a0124  adeC; adenine deaminase 1 [KO:K01486] [EC:3.5.4.2]
OV14_a0388  adeC; adenine deaminase 1 [KO:K01486] [EC:3.5.4.2]
OV14_2807  2`,3`-cyclic-nucleotide 2`-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
OV14_0240  putative phosphatase [KO:K09769] [EC:3.1.4.16]
OV14_2433  adenylate kinase [KO:K00939] [EC:2.7.4.3]
OV14_2540  putative MazG family protein [KO:K04765] [EC:3.6.1.9]
OV14_1388  putative metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
OV14_b1343  nodQ; NodQ bifunctional enzyme [KO:K00955] [EC:2.7.7.4 2.7.1.25]
OV14_1902  cysN; sulfate adenylyltransferase, subunit 1 [KO:K00956] [EC:2.7.7.4]
OV14_1903  cysD; sulfate adenylyltransferase, subunit 2 [KO:K00957] [EC:2.7.7.4]
OV14_b1344  nodP; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
OV14_3906  putative purine catabolism-related protein [KO:K07127] [EC:3.5.2.17]
OV14_a0411  putative purine catabolism-related protein [KO:K07127] [EC:3.5.2.17]
OV14_a0655  putative hydantoin-racemase [KO:K16841] [EC:5.1.99.3]
OV14_b0292  putative hydantoin-racemase [KO:K16841] [EC:5.1.99.3]
OV14_a1185  putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
OV14_b0512  dht; dihydropyrimidinase [KO:K01466] [EC:3.5.2.5]
OV14_3666  dht; dihydropyrimidinase [KO:K01466] [EC:3.5.2.5]
OV14_3909  putative polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
OV14_a0410  uricase [KO:K16842] [EC:3.5.2.5]
OV14_a0652  putative glyoxylate utilization [KO:K14977] [EC:3.5.3.26]
OV14_3907  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
OV14_a0408  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
OV14_4029  ureC; urease alpha subunit UreC [KO:K01428] [EC:3.5.1.5]
OV14_4032  ureB; urease beta subunit UreB [KO:K01429] [EC:3.5.1.5]
OV14_4034  ureA; urease subunit gamma UreA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ead00030  Pentose phosphate pathway
ead00220  Arginine biosynthesis
ead00250  Alanine, aspartate and glutamate metabolism
ead00260  Glycine, serine and threonine metabolism
ead00340  Histidine metabolism
ead00630  Glyoxylate and dicarboxylate metabolism
ead00730  Thiamine metabolism
ead00740  Riboflavin metabolism
ead00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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