KEGG   PATHWAY: kom00230
Entry
kom00230                    Pathway                                
Name
Purine metabolism - Klebsiella michiganensis M1
Class
Metabolism; Nucleotide metabolism
Pathway map
kom00230  Purine metabolism
kom00230

Module
kom_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:kom00230]
kom_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:kom00230]
kom_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:kom00230]
kom_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:kom00230]
kom_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:kom00230]
Other DBs
GO: 0006163 0042278
Organism
Klebsiella michiganensis M1 [GN:kom]
Gene
HR38_01565  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HR38_03215  nudE; adenosine nucleotide hydrolase [KO:K08312] [EC:3.6.1.-]
HR38_09050  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
HR38_13200  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HR38_03055  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HR38_21510  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HR38_24680  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HR38_06675  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HR38_25320  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HR38_22150  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
HR38_25615  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
HR38_25315  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
HR38_11935  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
HR38_11940  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HR38_25245  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HR38_16070  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HR38_06680  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HR38_11765  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HR38_11815  ushA; 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
HR38_27145  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HR38_08385  5'-nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HR38_13115  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
HR38_03225  nucleotidase [KO:K20881] [EC:3.1.3.-]
HR38_11800  guanosine kinase [KO:K00892] [EC:2.7.1.73]
HR38_24960  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
HR38_09055  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
HR38_11180  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
HR38_20955  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HR38_25795  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HR38_09870  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HR38_25380  inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
HR38_25450  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HR38_09100  yjjX; inositol monophosphatase [KO:K01529] [EC:3.6.1.73]
HR38_01080  nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
HR38_10515  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
HR38_25375  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
HR38_25035  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
HR38_18630  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
HR38_09720  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
HR38_15275  guanine deaminase [KO:K01487] [EC:3.5.4.3]
HR38_04490  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HR38_26520  hypothetical protein [KO:K00525] [EC:1.17.4.1]
HR38_24265  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HR38_24270  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HR38_26525  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HR38_07945  ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
HR38_10135  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HR38_24540  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
HR38_04500  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HR38_25350  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HR38_06110  guanosine polyphosphate pyrophosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HR38_27280  relA; (p)ppGpp synthetase [KO:K00951] [EC:2.7.6.5]
HR38_06235  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
HR38_07580  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
HR38_20250  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
HR38_22650  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
HR38_27345  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
HR38_23655  adenine deaminase [KO:K01486] [EC:3.5.4.2]
HR38_07740  cpdB; 2', 3'-cyclic nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
HR38_11790  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
HR38_27275  mazG; nucleoside triphosphate hydrolase [KO:K04765] [EC:3.6.1.9]
HR38_01555  diguanylate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HR38_08135  3',5'-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HR38_09415  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
HR38_27175  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
HR38_27180  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
HR38_27185  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
HR38_15255  monooxygenase [KO:K16839] [EC:1.14.13.113]
HR38_21655  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HR38_15270  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HR38_15265  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
HR38_15290  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
HR38_15295  allantoinase [KO:K16842] [EC:3.5.2.5]
HR38_15350  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
HR38_15345  aminotransferase V [KO:K00839] [EC:2.6.1.112]
HR38_01690  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HR38_01685  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
HR38_01680  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HR38_15305  amidase [KO:K22601] [EC:2.1.3.5]
HR38_15315  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
HR38_21580  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
kom00030  Pentose phosphate pathway
kom00220  Arginine biosynthesis
kom00250  Alanine, aspartate and glutamate metabolism
kom00260  Glycine, serine and threonine metabolism
kom00340  Histidine metabolism
kom00630  Glyoxylate and dicarboxylate metabolism
kom00730  Thiamine metabolism
kom00740  Riboflavin metabolism
kom00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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