KEGG   PATHWAY: kre00230
Entry
kre00230                    Pathway                                
Name
Purine metabolism - Komagataeibacter rhaeticus
Class
Metabolism; Nucleotide metabolism
Pathway map
kre00230  Purine metabolism
kre00230

Module
kre_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:kre00230]
kre_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:kre00230]
kre_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:kre00230]
kre_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:kre00230]
kre_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:kre00230]
Other DBs
GO: 0006163 0042278
Organism
Komagataeibacter rhaeticus [GN:kre]
Gene
GWK63_07270  NUDIX domain-containing protein [KO:K18447] [EC:3.6.1.21]
GWK63_08290  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
GWK63_01800  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
GWK63_01075  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
GWK63_01040  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
GWK63_04065  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
GWK63_09445  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
GWK63_09460  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
GWK63_09450  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
GWK63_04070  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
GWK63_04200  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
GWK63_04205  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
GWK63_09465  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
GWK63_09475  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
GWK63_14545  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GWK63_00555  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
GWK63_01790  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GWK63_09200  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
GWK63_04060  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
GWK63_00685  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
GWK63_10060  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
GWK63_04095  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
GWK63_04100  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
GWK63_05945  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
GWK63_05940  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
GWK63_09770  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
GWK63_07310  amidohydrolase family protein [KO:K01487] [EC:3.5.4.3]
GWK63_09845  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
GWK63_14460  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
GWK63_01640  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
GWK63_09145  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
GWK63_09140  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
GWK63_03245  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
GWK63_03495  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GWK63_04085  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GWK63_08955  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GWK63_05210  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
GWK63_08280  3',5'-cyclic-nucleotide phosphodiesterase [KO:K01120] [EC:3.1.4.17]
GWK63_03135  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
GWK63_08045  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
GWK63_01450  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
GWK63_00990  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
GWK63_07995  adenine deaminase [KO:K01486] [EC:3.5.4.2]
GWK63_15520  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
GWK63_15560  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
GWK63_01445  YmdB family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
GWK63_11100  adenylate kinase [KO:K00939] [EC:2.7.4.3]
GWK63_03110  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
GWK63_08770  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
GWK63_08765  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GWK63_04115  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
GWK63_04155  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
GWK63_04150  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
GWK63_05745  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
GWK63_04145  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
GWK63_04135  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
GWK63_04140  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
GWK63_04130  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
kre00030  Pentose phosphate pathway
kre00220  Arginine biosynthesis
kre00250  Alanine, aspartate and glutamate metabolism
kre00260  Glycine, serine and threonine metabolism
kre00340  Histidine metabolism
kre00630  Glyoxylate and dicarboxylate metabolism
kre00730  Thiamine metabolism
kre00740  Riboflavin metabolism
kre00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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