KEGG PATHWAY: lrj00564

PATHWAY: lrj00564

Entry

lrj00564                    Pathway

Name

Glycerophospholipid metabolism - Lethenteron reissneri (Far Eastern brook lamprey)

Class

Metabolism; Lipid metabolism

Pathway map

lrj00564

Glycerophospholipid metabolism

Module

lrj_M00090

Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:lrj00564]

lrj_M00091

Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:lrj00564]

Other DBs

GO:

0006650

Organism

Lethenteron reissneri (Far Eastern brook lamprey) [GN:lrj]

Gene

133344734

GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]

133346167

glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]

133345993

GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]

133343405

GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]

133345466

LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]

133351777

GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]

133352421

AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]

133353205

AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]

133347432

AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]

133341403

LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]

133353043

lysophospholipid acyltransferase 1-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]

133349244

lysophospholipid acyltransferase 1-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]

133341436

GNPAT; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]

133351864

phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]

133352074

phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]

133359062

phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]

133346527

phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]

133344086

LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN1-like [KO:K15728] [EC:3.1.3.4]

133353207

phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]

133343553

phospholipid phosphatase 5-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]

133343522

DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]

133350176

diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]

133344771

diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]

133351328

diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]

133357639

diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]

133346230

diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]

133353981

diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]

133359457

choline/ethanolaminephosphotransferase 1-like [KO:K13644] [EC:2.7.8.1 2.7.8.2]

133360266

choline/ethanolaminephosphotransferase 1-like [KO:K13644] [EC:2.7.8.1 2.7.8.2]

133357641

phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]

133353958

phospholipase D1-like [KO:K01115] [EC:3.1.4.4]

133341266

5'-3' exonuclease PLD3-like [KO:K16860] [EC:3.1.4.4]

133342290

5'-3' exonuclease PLD3-like [KO:K16860] [EC:3.1.4.4]

133350557

PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]

133351140

phospholipase A2 A2-actitoxin-Cgg2a-like [KO:K01047] [EC:3.1.1.4]

133351160

basic phospholipase A2 4-like [KO:K01047] [EC:3.1.1.4]

133351187

neutral phospholipase A2 3-like [KO:K01047] [EC:3.1.1.4]

133351217

phospholipase A2 A2-actitoxin-Cgg2a-like [KO:K01047] [EC:3.1.1.4]

133351218

neutral phospholipase A2 3-like [KO:K01047] [EC:3.1.1.4]

133351219

basic phospholipase A2 PA-9C-like [KO:K01047] [EC:3.1.1.4]

133351235

phospholipase A2 A2-actitoxin-Cgg2a-like [KO:K01047] [EC:3.1.1.4]

133351281

basic phospholipase A2 textilotoxin A chain-like [KO:K01047] [EC:3.1.1.4]

133354393

group XIIA secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]

133354396

group XIIA secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]

133345565

PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]

133341684

PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]

133357902

85/88 kDa calcium-independent phospholipase A2-like [KO:K16343] [EC:3.1.1.4]

133357909

85/88 kDa calcium-independent phospholipase A2-like isoform X1 [KO:K16343] [EC:3.1.1.4]

133358664

PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]

133347022

PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]

133356238

phospholipase B1, membrane-associated-like isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]

133359867

phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]

133359930

phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]

133350955

lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]

133354791

lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]

133344300

acyl-protein thioesterase 1-like [KO:K06128] [EC:3.1.1.5]

133352903

acyl-protein thioesterase 1-like [KO:K06128] [EC:3.1.1.5]

133352917

acyl-protein thioesterase 1-like [KO:K06128] [EC:3.1.1.5]

133350926

PLA2G15; phospholipase A2 group XV [KO:K06129] [EC:3.1.1.5]

133341815

PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]

133347301

GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]

133341901

CHAT; choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]

133353878

ACHE; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]

133350243

choline/ethanolamine kinase-like [KO:K14156] [EC:2.7.1.32 2.7.1.82]

133351485

choline kinase alpha-like isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]

133347490

choline kinase alpha-like [KO:K14156] [EC:2.7.1.32 2.7.1.82]

133361008

choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]

133362893

choline-phosphate cytidylyltransferase A-like [KO:K00968] [EC:2.7.7.15]

133347892

SELENOI; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]

133360320

ethanolamine kinase 1-like [KO:K00894] [EC:2.7.1.82]

133346895

uncharacterized protein LOC133346895 [KO:K05929] [EC:2.1.1.103]

133342352

uncharacterized protein LOC133342352 [KO:K05929] [EC:2.1.1.103]

133350706

ethanolamine-phosphate phospho-lyase-like [KO:K14286] [EC:4.2.3.2]

133353486

PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]

133350577

CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]

133354512

phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]

133342104

phospholipase A1 member A-like isoform X1 [KO:K13618] [EC:3.1.1.111]

133342105

phospholipase A1 member A-like [KO:K13618] [EC:3.1.1.111]

133340861

PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]

133350309

phosphatidylserine synthase 2-like [KO:K08730] [EC:2.7.8.29]

133351547

phosphatidylserine synthase 2-like [KO:K08730] [EC:2.7.8.29]

133348588

PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]

133361834

CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]

133355494

tafazzin [KO:K13511] [EC:2.3.1.-]

133359905

LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]

133345681

MBOAT7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]

133347827

LOW QUALITY PROTEIN: lysophospholipid acyltransferase 7-like [KO:K13516] [EC:2.3.1.-]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

lrj00010