KEGG   PATHWAY: meti00630
Entry
meti00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylobacterium radiodurans
Class
Metabolism; Carbohydrate metabolism
Pathway map
meti00630  Glyoxylate and dicarboxylate metabolism
meti00630

Module
meti_M00621  Glycine cleavage system [PATH:meti00630]
meti_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:meti00630]
Other DBs
GO: 0046487 0043648
Organism
Methylobacterium radiodurans [GN:meti]
Gene
DK427_00845  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DK427_14770  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DK427_01380  malate synthase G [KO:K01638] [EC:2.3.3.9]
DK427_04435  malate synthase G [KO:K01638] [EC:2.3.3.9]
DK427_01930  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DK427_05615  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DK427_18525  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
DK427_15545  succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
DK427_15540  ADP-forming succinate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
DK427_13055  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DK427_11265  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DK427_05735  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DK427_02330  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DK427_05730  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
DK427_17370  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
DK427_18535  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
DK427_08650  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DK427_18530  protein meaA [KO:K14447] [EC:5.4.99.63]
DK427_01745  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
DK427_20415  hypothetical protein [KO:K14449] [EC:4.2.1.148]
DK427_15555  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
DK427_17480  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
DK427_15340  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
DK427_24965  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
DK427_15230  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DK427_02600  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DK427_00980  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
DK427_06770  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
DK427_06765  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DK427_16740  catalase [KO:K03781] [EC:1.11.1.6]
DK427_04440  catalase [KO:K03781] [EC:1.11.1.6]
DK427_17230  catalase [KO:K03781] [EC:1.11.1.6]
DK427_21635  catalase [KO:K03781] [EC:1.11.1.6]
DK427_07690  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
DK427_02445  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DK427_15525  glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
DK427_10705  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DK427_21565  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DK427_24145  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DK427_15520  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DK427_03195  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DK427_17165  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DK427_04515  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DK427_07370  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DK427_01055  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DK427_01045  glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DK427_04340  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DK427_12520  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DK427_12410  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DK427_01965  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DK427_01050  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DK427_04375  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DK427_04370  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DK427_18130  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DK427_04365  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DK427_08970  glycerate kinase [KO:K11529] [EC:2.7.1.165]
DK427_04360  glycerate kinase [KO:K11529] [EC:2.7.1.165]
DK427_21155  glycerate kinase [KO:K11529] [EC:2.7.1.165]
DK427_21080  fumarate hydrolyase [KO:K03780] [EC:4.2.1.32]
DK427_22515  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DK427_08965  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DK427_14445  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DK427_01350  oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
DK427_04045  peptidase [KO:K00126] [EC:1.17.1.9]
DK427_24375  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
DK427_04050  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DK427_20800  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DK427_20795  NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
DK427_24370  formate dehydrogenase [KO:K00124]
DK427_04055  formate dehydrogenase [KO:K00124]
DK427_24365  formate dehydrogenase subunit gamma [KO:K00127]
DK427_04060  formate dehydrogenase subunit gamma [KO:K00127]
DK427_23550  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
DK427_23825  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
DK427_06335  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DK427_08795  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
meti00010  Glycolysis / Gluconeogenesis
meti00020  Citrate cycle (TCA cycle)
meti00030  Pentose phosphate pathway
meti00053  Ascorbate and aldarate metabolism
meti00071  Fatty acid degradation
meti00230  Purine metabolism
meti00250  Alanine, aspartate and glutamate metabolism
meti00260  Glycine, serine and threonine metabolism
meti00620  Pyruvate metabolism
meti00710  Carbon fixation in photosynthetic organisms
meti00750  Vitamin B6 metabolism
meti00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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