KEGG   PATHWAY: mhar00230
Entry
mhar00230                   Pathway                                
Name
Purine metabolism - Mariluticola halotolerans
Class
Metabolism; Nucleotide metabolism
Pathway map
mhar00230  Purine metabolism
mhar00230

Module
mhar_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mhar00230]
mhar_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mhar00230]
mhar_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mhar00230]
mhar_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mhar00230]
mhar_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mhar00230]
mhar_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mhar00230]
Other DBs
GO: 0006163 0042278
Organism
Mariluticola halotolerans [GN:mhar]
Gene
L1P08_09140  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
L1P08_00720  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
L1P08_00080  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
L1P08_04115  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
L1P08_07765  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
L1P08_04250  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
L1P08_05165  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
L1P08_05135  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
L1P08_05150  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
L1P08_04245  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
L1P08_13810  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
L1P08_13815  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
L1P08_05130  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
L1P08_05110  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
L1P08_11690  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
L1P08_00025  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
L1P08_13325  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
L1P08_03505  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
L1P08_09160  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
L1P08_11715  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
L1P08_00085  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
L1P08_02310  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
L1P08_03975  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
L1P08_10875  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
L1P08_05065  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
L1P08_15720  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
L1P08_15725  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
L1P08_02330  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
L1P08_15760  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
L1P08_04035  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
L1P08_02520  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
L1P08_03555  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
L1P08_07420  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
L1P08_06695  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
L1P08_02295  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
L1P08_04225  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
L1P08_14070  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
L1P08_14510  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
L1P08_04200  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
L1P08_15795  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
L1P08_00455  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
L1P08_13945  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
L1P08_04585  adenylate kinase [KO:K00939] [EC:2.7.4.3]
L1P08_03170  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
L1P08_06150  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
L1P08_06155  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
L1P08_15715  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
L1P08_15710  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
L1P08_15695  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
L1P08_15690  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
L1P08_13165  fumarylacetoacetate hydrolase family protein [KO:K16856] [EC:4.3.2.3]
L1P08_00785  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
L1P08_00800  urease subunit beta [KO:K01429] [EC:3.5.1.5]
L1P08_00810  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mhar00030  Pentose phosphate pathway
mhar00220  Arginine biosynthesis
mhar00250  Alanine, aspartate and glutamate metabolism
mhar00260  Glycine, serine and threonine metabolism
mhar00340  Histidine metabolism
mhar00630  Glyoxylate and dicarboxylate metabolism
mhar00730  Thiamine metabolism
mhar00740  Riboflavin metabolism
mhar00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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