KEGG   PATHWAY: mjv00330
Entry
mjv00330                    Pathway                                
Name
Arginine and proline metabolism - Manis javanica (Malayan pangolin)
Class
Metabolism; Amino acid metabolism
Pathway map
mjv00330  Arginine and proline metabolism
mjv00330

Module
mjv_M00015  Proline biosynthesis, glutamate => proline [PATH:mjv00330]
mjv_M00047  Creatine pathway [PATH:mjv00330]
mjv_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mjv00330]
mjv_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mjv00330]
mjv_M00970  Proline degradation, proline => glutamate [PATH:mjv00330]
mjv_M00972  Proline metabolism [PATH:mjv00330]
Other DBs
GO: 0006525 0006560
Organism
Manis javanica (Malayan pangolin) [GN:mjv]
Gene
108400260  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
108399435  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
108384483  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
108400048  creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
108407047  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
108391017  CKM; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
108401815  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
108391560  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
108390747  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
108396545  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
108387447  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
108391836  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
108399243  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
108406796  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
108410110  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
108409202  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
108400301  ALDH16A1; aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
108401917  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
108402717  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
108409039  CNDP1; beta-Ala-His dipeptidase isoform X1 [KO:K05604] [EC:3.4.13.20]
108409041  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
108393146  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
108404273  SAT2; thialysine N-epsilon-acetyltransferase isoform X1 [KO:K00657] [EC:2.3.1.57]
108392771  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
108383239  MAOA; amine oxidase [flavin-containing] A isoform X1 [KO:K00274] [EC:1.4.3.4]
108400916  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
108389628  AGMAT; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
108397443  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
108397044  NOS2; nitric oxide synthase, inducible isoform X3 [KO:K13241] [EC:1.14.13.39]
108391841  NOS3; nitric oxide synthase, endothelial [KO:K13242] [EC:1.14.13.39]
108401161  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
108402088  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
108403025  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
108402596  PYCR2; LOW QUALITY PROTEIN: pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
108402837  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
108395240  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
108395185  proline dehydrogenase 1, mitochondrial isoform X2 [KO:K00318] [EC:1.5.5.2]
108390809  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
108394923  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
108400146  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
108394425  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
108398850  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X2 [KO:K00472] [EC:1.14.11.2]
108404773  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X3 [KO:K00472] [EC:1.14.11.2]
108401524  PRODH2; hydroxyproline dehydrogenase isoform X2 [KO:K11394] [EC:1.5.5.3]
108410283  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
108409138  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
108390314  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
108399750  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
108385896  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
108399464  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mjv00020  Citrate cycle (TCA cycle)
mjv00220  Arginine biosynthesis
mjv00250  Alanine, aspartate and glutamate metabolism
mjv00260  Glycine, serine and threonine metabolism
mjv00270  Cysteine and methionine metabolism
mjv00310  Lysine degradation
mjv00410  beta-Alanine metabolism
mjv00470  D-Amino acid metabolism
mjv00480  Glutathione metabolism
mjv00630  Glyoxylate and dicarboxylate metabolism
mjv00650  Butanoate metabolism
mjv00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

DBGET integrated database retrieval system