KEGG   PATHWAY: mrv03083
Entry
mrv03083                    Pathway                                
Name
Polycomb repressive complex - Mauremys reevesii (Reeves's turtle)
Class
Genetic Information Processing; Chromosome
Pathway map
mrv03083  Polycomb repressive complex
mrv03083

Organism
Mauremys reevesii (Reeves's turtle) [GN:mrv]
Gene
120392159  EZH1; histone-lysine N-methyltransferase EZH1 isoform X1 [KO:K17451] [EC:2.1.1.356]
120397786  EZH2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
120395845  EED; polycomb protein EED isoform X1 [KO:K11462]
120383363  SUZ12; polycomb protein SUZ12 isoform X1 [KO:K11463]
120389274  RBBP4; histone-binding protein RBBP4 isoform X1 [KO:K10752]
120384975  RBBP7; histone-binding protein RBBP7 [KO:K11659]
120394883  PHF1; PHD finger protein 1 isoform X1 [KO:K11467]
120370161  MTF2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
120386885  PHF19; PHD finger protein 19 isoform X1 [KO:K11486]
120392220  elongin BC and Polycomb repressive complex 2-associated protein [KO:K26259]
120369015  uncharacterized protein LOC120369015 [KO:K26260]
120369016  ligand-dependent corepressor [KO:K26260]
120408001  AEBP2; zinc finger protein AEBP2 isoform X1 [KO:K17452]
120398497  JARID2; protein Jumonji isoform X1 [KO:K11478]
120409213  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
120401369  ASXL2; putative Polycomb group protein ASXL2 isoform X1 [KO:K11471]
120398000  ASXL3; putative Polycomb group protein ASXL3 isoform X1 [KO:K11471]
120381034  ASXL1; polycomb group protein ASXL1 isoform X1 [KO:K11471]
120371711  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
120388498  HCFC1; LOW QUALITY PROTEIN: host cell factor 1 [KO:K14966]
120404406  YY1; transcriptional repressor protein YY1 isoform X1 [KO:K09201]
120374349  MBD5; methyl-CpG-binding domain protein 5 isoform X1 [KO:K23219]
120391256  MBD6; methyl-CpG-binding domain protein 6 [KO:K26585]
120382823  FOXK2; forkhead box protein K2 [KO:K09404]
120373698  FOXK1; forkhead box protein K1 [KO:K09404]
120370333  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
120394885  RING1; E3 ubiquitin-protein ligase RING1 isoform X1 [KO:K10695] [EC:2.3.2.27]
120392272  PCGF2; polycomb group RING finger protein 2 isoform X1 [KO:K11460]
120398271  polycomb complex protein BMI-1 [KO:K11459]
120383205  CBX2; chromobox protein homolog 2 [KO:K11451]
120383206  CBX4; E3 SUMO-protein ligase CBX4 isoform X1 [KO:K11452] [EC:2.3.2.-]
120371880  CBX6; chromobox protein homolog 6 isoform X1 [KO:K11453]
120371896  CBX7; chromobox protein homolog 7 isoform X1 [KO:K11454]
120383207  CBX8; chromobox protein homolog 8 [KO:K11455]
120404261  PHC1; polyhomeotic-like protein 1 isoform X1 [KO:K11456]
120387840  PHC2; polyhomeotic-like protein 2 isoform X1 [KO:K11457]
120371526  PHC3; polyhomeotic-like protein 3 isoform X1 [KO:K11458]
120372659  SCML2; sex comb on midleg-like protein 2 isoform X1 [KO:K11465]
120389094  SCMH1; polycomb protein SCMH1 isoform X1 [KO:K11461]
120395300  SFMBT2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
120369115  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
120381926  aurora kinase C-like isoform X1 [KO:K11479] [EC:2.7.11.1]
120380505  aurora kinase C-like isoform X1 [KO:K11479] [EC:2.7.11.1]
120370294  UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X1 [KO:K06689] [EC:2.3.2.23]
120406058  UBE2D3; ubiquitin-conjugating enzyme E2 D3 [KO:K06689] [EC:2.3.2.23]
120369450  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
120371402  USP16; ubiquitin carboxyl-terminal hydrolase 16 [KO:K11844] [EC:3.4.19.12]
120402343  USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [KO:K11844] [EC:3.4.19.12]
120369125  RING1 and YY1-binding protein isoform X1 [KO:K11469]
120386401  YAF2; YY1-associated factor 2 isoform X1 [KO:K11468]
120406400  PCGF1; LOW QUALITY PROTEIN: polycomb group RING finger protein 1 [KO:K11487]
120393433  KDM2A; lysine-specific demethylase 2A isoform X1 [KO:K10276] [EC:1.14.11.27]
120386209  KDM2B; lysine-specific demethylase 2B isoform X1 [KO:K10276] [EC:1.14.11.27]
120403837  BCOR; BCL-6 corepressor isoform X1 [KO:K23215]
120372246  BCORL1; BCL-6 corepressor-like protein 1 isoform X1 [KO:K26199]
120369650  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
120373165  USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
120407963  PCGF3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
120369236  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
120392457  CSNK2B; casein kinase II subunit beta isoform X1 [KO:K03115]
120387273  AUTS2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
120403137  FBRS; probable fibrosin-1 isoform X1 [KO:K26253]
120385916  FBRSL1; fibrosin-1-like protein isoform X1 [KO:K26254]
120392162  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
120398072  TEX10; testis-expressed protein 10 isoform X1 [KO:K14827]
120372915  histone acetyltransferase p300-like isoform X1 [KO:K04498] [EC:2.3.1.48]
120373929  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
120369076  PCGF6; polycomb group RING finger protein 6 [KO:K11470]
120400800  E2F6; transcription factor E2F6 isoform X1 [KO:K09390]
120405860  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
120404691  MAX; protein max isoform X1 [KO:K04453]
120404991  MGA; MAX gene-associated protein isoform X1 [KO:K23399]
120382916  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
120401674  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 isoform X1 [KO:K24387]
120389169  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
120380576  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
120396347  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
120386618  WDR5; WD repeat-containing protein 5 [KO:K14963]
120401769  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
120389115  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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