KEGG ORTHOLOGY: K11457

ORTHOLOGY: K11457

Entry

K11457                      KO

Symbol

PHC2, EDR2

Name

polyhomeotic-like protein 2

Pathway

map03083

Polycomb repressive complex

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    K11457  PHC2, EDR2; polyhomeotic-like protein 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11457  PHC2, EDR2; polyhomeotic-like protein 2
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Canonical PRC1 (PRC1.2/1.4)
     K11457  PHC2, EDR2; polyhomeotic-like protein 2

Genes

HSA:	1912(PHC2)

PTR:	456729(PHC2)

PPS:	100986640(PHC2)

GGO:	101132460(PHC2)

PON:	100456902(PHC2)

PPYG:

129020004(PHC2)

NLE:	100587217(PHC2)

HMH:	116472908(PHC2)

SSYN:

129468916(PHC2)

MCC:	710201(PHC2)

MTHB:

126930067

MNI:	105494672(PHC2)

CSAB:

103225160(PHC2)

CATY:

105594800(PHC2)

PANU:

101020038(PHC2)

TGE:	112622903(PHC2)

MLEU:

105533929(PHC2)

RRO:	104677305(PHC2)

RBB:	108537277(PHC2)

TFN:	117092918(PHC2)

CANG:

105521253(PHC2)

CJC:	100406843(PHC2)

SBQ:	101033323(PHC2)

CIMI:

108303979(PHC2)

ANAN:

105708745(PHC2)

CSYR:

103258023(PHC2)

MMUR:

105871784(PHC2)

LCAT:

123635804(PHC2)

PCOQ:

105808632(PHC2)

OGA:	100944149(PHC2)

MMU:	54383(Phc2)

MCAL:

110292217(Phc2)

MPAH:

110323203(Phc2)

RNO:	313038(Phc2)

MCOC:

116095771(Phc2)

ASYL:

127681314(Phc2)

MUN:	110548745(Phc2)

CGE:	100756136(Phc2)

MAUA:

101828482(Phc2)

PROB:

127225385(Phc2)

PLEU:

114682055(Phc2) 114693562

PMAV:

102910324(Phc2)

MORG:

121448273(Phc2)

MFOT:

126507909

AAMP:

119817023(Phc2)

NGI:	103730906(Phc2)

HGL:	101700417(Phc2)

CPOC:

100732113(Phc2)

CCAN:

109686856

DORD:

105988791(Phc2)

DSP:	122106359(Phc2)

DMER:

138818007(Phc2)

PLOP:

125354881(Phc2)

NCAR:

124978066

MMMA:

107141519(Phc2)

OCU:

100351541

OPI:	101534151(PHC2)

OCZ:	121152222(PHC2)

TUP:	102492064(PHC2)

GVR:	103602663(PHC2)

CFA:	487297(PHC2)

CLUD:

112660567(PHC2)

VVP:	112931740(PHC2)

VLG:	121496736(PHC2)

NPO:	129513490(PHC2)

AML:	105238773(PHC2)

UMR:	103666420(PHC2)

UAR:	123782178(PHC2)

ELK:

111142791

LLV:

125096851

MPUF:

101693876(PHC2)

MNP:	132002159(PHC2)

MLK:	131810391(PHC2)

NVS:	122899724(PHC2)

ORO:	101366028(PHC2)

EJU:	114217016(PHC2)

ZCA:	113928054(PHC2)

MLX:	118019718(PHC2)

NSU:	110574869(PHC2)

LWW:	102726729(PHC2)

FCA:	101082329(PHC2)

PYU:	121025763(PHC2)

PCOO:

112872229(PHC2)

PBG:	122482125(PHC2)

PVIV:

125173085(PHC2)

LRUF:

124515078

LGF:	123597565(PHC2)

AJU:

106973221

PTG:	102949238(PHC2)

PPAD:

109255251(PHC2)

PUC:

125912796

PLEZ:

122226401(PHC2)

HHV:	120231512(PHC2)

BTA:	537511(PHC2)

BOM:	102276404(PHC2)

BIU:	109572136(PHC2)

BBUB:

102393256(PHC2)

BBIS:

104986401(PHC2)

CHX:	102181080(PHC2)

OAS:	101109942(PHC2)

BTAX:

128043304(PHC2)

CSUM:

138075413(PHC2)

ODA:	120854238(PHC2)

CCAD:

122426219(PHC2)

MREE:

136164829(PHC2)

OVR:	110138755(PHC2)

MBEZ:

129537520(PHC2)

SSC:	100622975(PHC2)

CFR:	102512244(PHC2)

CBAI:

105066744(PHC2)

CDK:	105085773(PHC2)

VPC:	102535530(PHC2)

BACU:

103009801(PHC2)

BMUS:

118890628(PHC2)

LVE:	103077048(PHC2)

OOR:	101286172(PHC2)

LALB:

132514972(PHC2)

DDP:	132429870(PHC2)

DLE:	111175543(PHC2)

PCAD:

102982582(PHC2)

PPHC:

136119953(PHC2)

ECB:	100070002(PHC2)

EAI:	106829028(PHC2)

MYB:	102251261(PHC2)

MYD:	102755437(PHC2)

MMYO:

118675053(PHC2)

MLF:	102418161(PHC2)

MDT:	132231343(PHC2)

MYUM:

139003150(PHC2)

PKL:	118724789(PHC2)

EFUS:

103300117(PHC2)

MNA:	107541090(PHC2)

DRO:	112299335(PHC2)

SHON:

118997699(PHC2)

AJM:	119052240(PHC2)

PDIC:

114496335(PHC2)

PHAS:

123831633(PHC2)

MMF:	118626354(PHC2)

HAI:	109390734(PHC2)

RFQ:	117026681(PHC2)

PALE:

102884964(PHC2)

PGIG:

120582034(PHC2)

PVP:	105290603(PHC2)

RAY:	107513618(PHC2)

MJV:	108401812(PHC2)

TOD:	119236683(PHC2)

SARA:

101540231(PHC2)

SFUM:

130031586(PHC2)

SETR:

126011035(PHC2)

LAV:

100671391

TMU:

101351567

ETF:	101657932(PHC2)

MDO:	100026907(PHC2)

GAS:	123240419(PHC2)

SHR:	100920376(PHC2)

AFZ:

127555570

PCW:	110206210(PHC2)

TVP:	118837909(PHC2)

MLAO:

141508851(PHC2)

OAA:	100091900(PHC2)

TACU:

119928618(PHC2)

GGA:	100857390(PHC2)

PCOC:

116238354(PHC2)

MGP:

104914207

CJO:	107323264(PHC2)

TPAI:

128085005(PHC2)

NMEL:

110386989(PHC2)

APLA:

101795058(PHC2)

ACYG:

106048622(PHC2)

CATA:

118258821(PHC2)

AFUL:

116497726(PHC2)

TGU:	100232462(PHC2)

LSR:	110474428(PHC2)

SCAN:

103820957

PMOA:

120496757(PHC2)

OTC:	121344121(PHC2)

PRUF:

121351350

ATRC:

139600824(PHC2)

OMA:	130261616(PHC2)

PHI:	102108423(PHC2)

PMAJ:

107213546(PHC2)

CCAE:

111943830(PHC2)

CCW:	104698584(PHC2)

ETL:	114071504(PHC2)

ZLE:	135456592(PHC2)

SVG:

106860505

MMEA:

130581832(PHC2)

HRT:	120762434(PHC2)

SATI:

136370854(PHC2)

CCIC:

134052896(PHC2)

SHAB:

115617507(PHC2)

SURA:

141953860(PHC2)

TALA:

116962693(PHC2)

ACHC:

115343273(PHC2)

AGEN:

126034947

HHAR:

128143755

PPUS:

135190689(PHC2)

CBOR:

142092192

CBOY:

140661551(PHC2)

MAME:

142418565(PHC2)

CNIC:

135997371(PHC2)

CUCA:

104062259(PHC2)

GAME:

129215766(PHC2)

LMIC:

141732129(PHC2)

NPD:	112959560(PHC2)

ASN:	102384517(PHC2)

AMJ:	102569973(PHC2)

CPOO:

109314285(PHC2)

CIZ:	142000913(PHC2)

CMY:	102939391(PHC2)

CCAY:

125624440(PHC2)

DCC:	119845115(PHC2)

CPIC:

101951633(PHC2)

TST:	117867875(PHC2)

CABI:

116835567(PHC2)

MRV:	120387840(PHC2)

ACS:	100555443(phc2)

ASAO:

132764964

PVT:	110072634(PHC2)

SUND:

121936247(PHC2)

PBI:	103048885(PHC2)

PMUR:

107291364(PHC2)

CTIG:

120319071(PHC2)

TSR:

106552970

PGUT:

117669650(PHC2)

PCAE:

139326205(PHC2)

APRI:

131186943(PHC2)

PTEX:

113453324

NSS:

113429533

VKO:	123034701(PHC2)

PMUA:

114602331(PHC2)

PRAF:

128419549(PHC2)

ZVI:	118086149(PHC2)

HCG:	128338716(PHC2)

GJA:

107113363

STOW:

125445773(PHC2)

EMC:	129344711(PHC2)

XLA:	108697275 734530(phc2.L)

XTR:	100127572(phc2)

NPR:

108802716

RTEM:

120916177(PHC2)

ACAT:

141110207(PHC2)

PADS:

140340807(PHC2)

BBUF:

120994991(PHC2)

BGAR:

122927031(PHC2)

DTC:

141085076

PWL:	138300667(PHC2)

MUO:	115456566(PHC2)

GSH:	117349199(PHC2)

DRE:	394177(phc2b)

SRX:	107708163 107729766 107737567

SANH:

107655778 107666120 107703065

SGH:	107549300 107569800 107591107

CCAR:

109055098 109092199(phc2b) 109092204

CAUA:

113050291 113068389 113068884 113105131

CGIB:

127944979 127959346 128012017 128015902

PTET:

122329164(phc2a) 122332233 122347496(phc2b)

LROH:

127154751(phc2a) 127167292(phc2b)

GRF:	141346586(phc2b)

OMC:	131532534(phc2a) 131543087(phc2b)

PPRM:

120463458(phc2a) 120493954(phc2b)

RKG:	130102195(phc2a) 130104161(phc2b)

MAMB:

125259649(phc2a) 125273514(phc2b)

CIDE:

127504707 127514181

CERY:

137009338(phc2a) 137011443(phc2b)

MASI:

127418995 127419682 127446464 127449341

TROS:

130545558(phc2a) 130556894(phc2b)

TDW:	130409670(phc2a) 130425239(phc2b)

MANU:

129430698(phc2a) 129450090(phc2b)

PDAB:

135770059(phc2b) 135775567(phc2a)

IPU:	108272160(phc2b) 108275961(phc2a)

IFU:	128614741(phc2b) 128618905(phc2a)

PHYP:

113530741 113530748

SMEO:

124387327(phc2b)

TFD:	113643240(phc2b) 113658268(phc2a)

TVC:	132844552(phc2b) 132861930(phc2a)

CGAR:

128510728(phc2a) 128527216(phc2b)

NGRA:

132885120(phc2b) 132897011(phc2a)

TRN:	134316279(phc2b) 134333538(phc2a)

AMEX:

103036390(phc2b) 103043307(phc2a)

CMAO:

118808433(phc2b)

EEE:	113569991 113583088

CHAR:

105908313(phc2b)

SPIL:

134087099(phc2a) 134093102

ASAD:

121706773(phc2b) 121712756(phc2a)

TRU:	101073773 101076337

TFS:	130524922(phc2b)

TNG:	GSTEN00033913G001

LCO:	104928077 104937971

NCC:	104943370(phc2)

TBEN:

117489825(phc2b)

CGOB:

115008254 115021885

PGEO:

117446974(phc2b)

GACU:

117539549

EMAC:

134883589(phc2b)

ELY:	117257037(phc2b) 117258869

EFO:	125880662(phc2b) 125892037(phc2a)

PLEP:

121947309 121959549(phc2b)

SLUC:

116051489(phc2b) 116058666(phc2a)

ECRA:

117944041(phc2b)

ESP:	116688055(phc2)

PFLV:

114554516 114558904

GAT:	120829233(phc2a) 120835716(phc2b)

PPUG:

119201073(phc2a) 119230057(phc2b)

AFB:	129099394(phc2a) 129105493(phc2b)

CLUM:

117731104(phc2b) 117733255

PSWI:

130208570(phc2b)

CANA:

137796576(phc2b) 137800105

CVE:	137868554(phc2b) 137889723

MSAM:

119885503(phc2b) 119904982(phc2a)

SCHU:

122883239(phc2b) 122883738(phc2a)

CUD:	121505968(phc2b) 121517220(phc2a)

SPUL:

138590220 138605990(phc2b)

LMIX:

132976871(phc2b) 132989761(phc2a)

HTC:	141792806(phc2b)

ALAT:

119021528(phc2b) 119022243

ASTR:

137595788(phc2b)

MZE:	101474417 101476974

ONL:	100708466 100709540

OAU:	116309994(phc2a) 116320291(phc2b)

OLA:	101159094 101162031

OML:	112140869(phc2a) 112145804(phc2b)

CSAI:

133448402(phc2b) 133456905(phc2a)

XMA:	102219498 102227010

XCO:	114136149 114142440

XHE:

116721416

PRET:

103464731(phc2)

PFOR:

103134625 103154236

PLAI:

106956509 106960217

PMEI:

106918247 106926565

GAF:	122822143 122832863 122833459(phc2b)

PPRL:

129371837(phc2a) 129372672(phc2b)

CVG:	107089155 107100401

CTUL:

119773557(phc2b) 119799194(phc2a)

GMU:	124856757(phc2b) 124861564(phc2a)

NFU:	107385013 107391374

KMR:	108231689(phc2b) 108250886(phc2a)

ALIM:

106518312 106529361

NWH:	119412741(phc2b) 119429195

AOCE:

111571772(phc2a) 111580041(phc2b)

EJA:	138197969(phc2b)

BFRE:

138616681(phc2b) 138636911(phc2a)

MCEP:

125006862(phc2b) 125015572

CSEM:

103384864 103386594

POV:	109630668 109635394

SSEN:

122768327(phc2b) 122776739(phc2a)

SSOE:

131460827(phc2b) 131469227(phc2a)

HHIP:

117761130(phc2b) 117765164(phc2a)

HSP:	118104900(phc2b) 118110488(phc2a)

PPLT:

128441790 128457110(phc2b)

SMAU:

118309518(phc2b) 118316207

LCF:	108888081 108900473(phc2a)

SDU:	111233574 111233776

SLAL:

111657932 111658860

XGL:	120783305(phc2b) 120804341(phc2a)

HCQ:	109507630 109528523

SSCV:

125977779(phc2b) 125987692

SBIA:

133507845(phc2b)

PEE:	133408238(phc2b)

PTAO:

133483694(phc2b)

BPEC:

110174612

ENY:	140365626(phc2b)

MALB:

109951043 109966983

BSPL:

114855277(phc2b) 114859318(phc2a)

SJO:	128355180(phc2b) 128357925

SSCO:

133977879(phc2b) 133988307

TTY:	137181148(phc2b) 137183979

GMH:

115556800

SASA:

106565865 106566819 106572235 106583010

STRU:

115150750 115166283 115168266 115207682

OTW:	112218854 112222077(phc2a) 112233068 112254452(phc2b)

OMY:	110492287 110494475 110527983 110532130

OGO:	124002526 124031807

ONE:	115102213 115132010 115138455 115143298

OKI:	109891027 109896830 109907868

OKE:	118388452 118400182

OMM:	135504540 135540111 135542060

OCLA:

139371197 139413430 139416376

SALP:

111966317 111968004 111969960

SNH:	120058712 120059702 120065114

SFON:

129815133 129830270 129850888

CCLU:

121538195 121574932 121577749

ELS:	105013817(phc2) 105028377

OEP:	134019032(phc2a) 134029508(phc2b)

SFM:	108918260 108933503

PKI:	111852039 111859162

AANG:

118208442 118211100(phc2b)

AROT:

135235041 135237777(phc2b)

CCOG:

133110048(phc2b) 133139351

LOC:	102698252(phc2)

PSPA:

121328293 121328601

ARUT:

117425787 117432417

PSEX:

120530905

LCM:	102350230(PHC2)

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

FAS:

DAM:

CSET:

AGB:

CSEC:

PCLA:

DSV:

VDE:

VJA:

GAE:

HRF:

HRJ:

CRG:

PMAX:

MMER:

MCAZ:

MFOO:

Reference

PMID:16024804

Authors

Isono K, Fujimura Y, Shinga J, Yamaki M, O-Wang J, Takihara Y, Murahashi Y, Takada Y, Mizutani-Koseki Y, Koseki H

Title

Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.

Journal

Mol Cell Biol 25:6694-706 (2005)
DOI:10.1128/MCB.25.15.6694-6706.2005

Sequence

[mmu:54383]

LinkDB

DBGET integrated database retrieval system