KEGG   PATHWAY: mshg00630
Entry
mshg00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium shigaense
Class
Metabolism; Carbohydrate metabolism
Pathway map
mshg00630  Glyoxylate and dicarboxylate metabolism
mshg00630

Module
mshg_M00012  Glyoxylate cycle [PATH:mshg00630]
mshg_M00621  Glycine cleavage system [PATH:mshg00630]
mshg_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mshg00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium shigaense [GN:mshg]
Gene
MSG_02708  aceA; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MSG_00686  icl; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MSG_04655  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MSG_02610  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MSG_03761  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MSG_04158  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MSG_04162  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MSG_03880  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
MSG_02147  acn; aconitate hydratase A [KO:K27802] [EC:4.2.1.3 4.2.1.99]
MSG_03618  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_03645  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_04084  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_04136  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_00442  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_02639  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_03951  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_04213  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_04531  fadA5; steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MSG_04510  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_04543  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSG_02493  transporter [KO:K00626] [EC:2.3.1.9]
MSG_03646  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MSG_01150  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
MSG_01155  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MSG_01154  hypothetical protein [KO:K27095]
MSG_03172  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MSG_02166  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MSG_02167  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MSG_04333  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MSG_04334  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MSG_03740  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MSG_02810  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MSG_03212  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MSG_00124  Catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MSG_04711  katA; catalase [KO:K03781] [EC:1.11.1.6]
MSG_03138  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MSG_03115  glnA1_2; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MSG_03123  glnA2; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MSG_01422  glnA1_1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MSG_02022  glnT; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MSG_02436  glnN; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MSG_02664  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MSG_03934  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MSG_02597  gcvP; putative glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MSG_01234  gcvPA_1; putative glycine dehydrogenase subunit 1 [KO:K00282] [EC:1.4.4.2]
MSG_03104  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MSG_00681  lpdC; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MSG_02592  gcvH; glycine cleavage system H protein [KO:K02437]
MSG_03098  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MSG_03757  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MSG_03033  oxdC; oxalate decarboxylase OxdC [KO:K01569] [EC:4.1.1.2]
MSG_00431  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MSG_00144  dehydrogenase [KO:K00123] [EC:1.17.1.9]
MSG_00145  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MSG_00146  4Fe-4S ferredoxin [KO:K00124]
MSG_01293  formamidase [KO:K01455] [EC:3.5.1.49]
MSG_00248  oxcA; oxalyl-CoA decarboxylase OxcA [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mshg00010  Glycolysis / Gluconeogenesis
mshg00020  Citrate cycle (TCA cycle)
mshg00030  Pentose phosphate pathway
mshg00053  Ascorbate and aldarate metabolism
mshg00071  Fatty acid degradation
mshg00230  Purine metabolism
mshg00250  Alanine, aspartate and glutamate metabolism
mshg00260  Glycine, serine and threonine metabolism
mshg00620  Pyruvate metabolism
mshg00710  Carbon fixation by Calvin cycle
mshg00750  Vitamin B6 metabolism
mshg00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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