KEGG   PATHWAY: parb00230
Entry
parb00230                   Pathway                                
Name
Purine metabolism - Paraburkholderia aromaticivorans
Class
Metabolism; Nucleotide metabolism
Pathway map
parb00230  Purine metabolism
parb00230

Module
parb_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:parb00230]
parb_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:parb00230]
parb_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:parb00230]
parb_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:parb00230]
parb_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:parb00230]
parb_M00546  Purine degradation, xanthine => urea [PATH:parb00230]
parb_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:parb00230]
parb_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:parb00230]
Other DBs
GO: 0006163 0042278
Organism
Paraburkholderia aromaticivorans [GN:parb]
Gene
CJU94_18465  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CJU94_01580  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
CJU94_03360  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CJU94_29285  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CJU94_18765  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CJU94_09185  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CJU94_19110  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
CJU94_15405  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CJU94_02495  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CJU94_08605  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CJU94_08600  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CJU94_08595  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CJU94_08125  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CJU94_08250  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CJU94_03265  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CJU94_03045  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CJU94_22870  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CJU94_15990  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CJU94_15950  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CJU94_07765  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CJU94_12985  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CJU94_12400  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CJU94_09515  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
CJU94_02270  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
CJU94_09755  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
CJU94_02265  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
CJU94_09750  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
CJU94_22555  aldehyde oxidase [KO:K11177] [EC:1.17.1.4]
CJU94_32450  acylaldehyde oxidase [KO:K11177] [EC:1.17.1.4]
CJU94_22560  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
CJU94_32455  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
CJU94_22565  2Fe-2S ferredoxin [KO:K13483]
CJU94_32460  (2Fe-2S)-binding protein [KO:K13483]
CJU94_05550  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CJU94_12995  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
CJU94_09735  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
CJU94_09530  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CJU94_07790  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CJU94_21025  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
CJU94_37055  hypothetical protein [KO:K00525] [EC:1.17.4.1]
CJU94_07795  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CJU94_37045  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CJU94_06955  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CJU94_09540  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CJU94_10710  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CJU94_11140  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
CJU94_25205  hypothetical protein [KO:K01768] [EC:4.6.1.1]
CJU94_35490  sensor protein Chase2 [KO:K01768] [EC:4.6.1.1]
CJU94_12470  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CJU94_07815  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CJU94_29475  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
CJU94_09740  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CJU94_08950  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CJU94_11590  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
CJU94_11900  phosphorylase [KO:K00988] [EC:2.7.7.5 2.7.7.53]
CJU94_01860  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
CJU94_16380  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CJU94_01925  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CJU94_01395  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CJU94_01400  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
CJU94_14785  monooxygenase [KO:K22879] [EC:1.14.13.113]
CJU94_21780  FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
CJU94_13715  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CJU94_13685  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
CJU94_13675  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
CJU94_11805  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
CJU94_13680  allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
CJU94_08020  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
CJU94_13690  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
CJU94_08025  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
CJU94_13695  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
CJU94_28995  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
CJU94_01545  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CJU94_01540  urease subunit beta [KO:K01429] [EC:3.5.1.5]
CJU94_01535  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
CJU94_34305  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
CJU94_15685  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
parb00030  Pentose phosphate pathway
parb00220  Arginine biosynthesis
parb00250  Alanine, aspartate and glutamate metabolism
parb00260  Glycine, serine and threonine metabolism
parb00340  Histidine metabolism
parb00630  Glyoxylate and dicarboxylate metabolism
parb00730  Thiamine metabolism
parb00740  Riboflavin metabolism
parb00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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