KEGG   PATHWAY: pleo00230
Entry
pleo00230                   Pathway                                
Name
Purine metabolism - Pleomorphomonas sp. SM30
Class
Metabolism; Nucleotide metabolism
Pathway map
pleo00230  Purine metabolism
pleo00230

Module
pleo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pleo00230]
pleo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pleo00230]
pleo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pleo00230]
pleo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pleo00230]
pleo_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pleo00230]
pleo_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pleo00230]
Other DBs
GO: 0006163 0042278
Organism
Pleomorphomonas sp. SM30 [GN:pleo]
Gene
OHA_1_02795  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
OHA_1_00903  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
OHA_1_01727  algC; phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
OHA_1_02220  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
OHA_1_00100  purF; amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
OHA_1_01855  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
OHA_1_00208  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
OHA_1_01124  purL_2; phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
OHA_1_01117  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
OHA_1_01120  purQ; phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
OHA_1_00210  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
OHA_1_03651  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
OHA_1_03650  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
OHA_1_01116  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
OHA_1_00027  fumC; fumarate hydratase, class II [KO:K01756] [EC:4.3.2.2]
OHA_1_02682  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
OHA_1_04124  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
OHA_1_03493  yfkN; trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
OHA_1_00624  surE_1; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
OHA_1_01698  surE_2; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
OHA_1_02799  punA; purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
OHA_1_02217  yfiH; laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
OHA_1_02731  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
OHA_1_01053  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
OHA_1_01013  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
OHA_1_03585  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
OHA_1_00058  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
OHA_1_00579  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
OHA_1_00580  xdhA; xanthine dehydrogenase molybdenum-binding subunit [KO:K13482] [EC:1.17.1.4]
OHA_1_01047  guaA_1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
OHA_1_03319  guaA_2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
OHA_1_01720  guaD_2; guanine deaminase [KO:K01487] [EC:3.5.4.3]
OHA_1_00839  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
OHA_1_00289  nrdJ; vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
OHA_1_01180  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
OHA_1_00606  hypothetical protein [KO:K06952] [EC:3.1.3.89]
OHA_1_00736  rsh_1; GTP pyrophosphokinase rsh [KO:K01139] [EC:2.7.6.5 3.1.7.2]
OHA_1_00215  gppA; guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
OHA_1_01056  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
OHA_1_01308  CYTH domain protein [KO:K01768] [EC:4.6.1.1]
OHA_1_01353  cyaA_2; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
OHA_1_01041  cyaA_1; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
OHA_1_03727  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
OHA_1_02794  add2; aminodeoxyfutalosine deaminase [KO:K01488] [EC:3.5.4.4]
OHA_1_01794  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
OHA_1_01949  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
OHA_1_00701  cpdB; 2', 3'-cyclic-nucleotide2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
OHA_1_03701  hypothetical protein [KO:K09769] [EC:3.1.4.16]
OHA_1_01261  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
OHA_1_00905  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
OHA_1_00369  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
OHA_1_01227  cysNC; bifunctional enzyme CysN/CysC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
OHA_1_01228  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
OHA_1_01485  putative glutamate synthase subunit beta [KO:K22879] [EC:1.14.13.113]
OHA_1_00486  dihydropyrimidine dehydrogenase subunit A [KO:K22879] [EC:1.14.13.113]
OHA_1_01086  dihydropyrimidine dehydrogenase subunit A [KO:K22879] [EC:1.14.13.113]
OHA_1_00578  pucM; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
OHA_1_00640  pucL; uric acid degradation bifunctional protein PucL [KO:K13485] [EC:4.1.1.97]
OHA_1_02866  Asp/Glu/Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
OHA_1_02973  Asp/Glu/Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
OHA_1_01083  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
OHA_1_00165  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
OHA_1_00641  amaB_1; N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
OHA_2_00081  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
OHA_1_02716  ureC1; urease subunit alpha 1 [KO:K01428] [EC:3.5.1.5]
OHA_1_02713  ureB1; urease subunit beta 1 [KO:K01429] [EC:3.5.1.5]
OHA_1_02711  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
OHA_2_00080  ureA; urease subunit alpha [KO:K14048] [EC:3.5.1.5]
OHA_2_00015  ywrD; putative gamma-glutamyltransferase YwrD [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pleo00030  Pentose phosphate pathway
pleo00220  Arginine biosynthesis
pleo00250  Alanine, aspartate and glutamate metabolism
pleo00260  Glycine, serine and threonine metabolism
pleo00340  Histidine metabolism
pleo00630  Glyoxylate and dicarboxylate metabolism
pleo00730  Thiamine metabolism
pleo00740  Riboflavin metabolism
pleo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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