KEGG   PATHWAY: pmrn00564
Entry
pmrn00564                   Pathway                                
Name
Glycerophospholipid metabolism - Petromyzon marinus (sea lamprey)
Class
Metabolism; Lipid metabolism
Pathway map
pmrn00564  Glycerophospholipid metabolism
pmrn00564

Module
pmrn_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pmrn00564]
pmrn_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pmrn00564]
pmrn_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pmrn00564]
Other DBs
GO: 0006650
Organism
Petromyzon marinus (sea lamprey) [GN:pmrn]
Gene
116941082  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
116938252  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
116938648  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
116940558  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
116947467  glycerol-3-phosphate acyltransferase 4-like [KO:K13506] [EC:2.3.1.15]
116941389  glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
116957423  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
116958137  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
116953018  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
116953295  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
116950919  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
116947761  LCLAT1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
116946545  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
116942671  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
116947732  GNPAT; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
116948805  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
116942108  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
116948913  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
116948915  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
116943758  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
116937904  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
116951947  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
116941734  phosphatidate phosphatase LPIN3-like isoform X1 [KO:K15728] [EC:3.1.3.4]
116942620  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
116945180  phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]
116940729  phospholipid phosphatase 4-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
116945674  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
116952594  LOW QUALITY PROTEIN: diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]
116940025  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
116940696  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
116954547  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
116941046  diacylglycerol kinase beta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
116955198  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
116938745  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
116958677  cholinephosphotransferase 1-like isoform X1 [KO:K00994] [EC:2.7.8.2]
116956389  choline/ethanolaminephosphotransferase 1-like [KO:K13644] [EC:2.7.8.1 2.7.8.2]
116954540  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
116956727  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
116952528  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
116947891  phospholipase D3-like isoform X1 [KO:K16860] [EC:3.1.4.4]
116943323  phospholipase D3-like [KO:K16860] [EC:3.1.4.4]
116946826  basic phospholipase A2 textilotoxin A chain-like [KO:K01047] [EC:3.1.1.4]
116946827  basic phospholipase A2 textilotoxin A chain-like [KO:K01047] [EC:3.1.1.4]
116946955  acidic phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
116946956  basic phospholipase A2 PA-9C-like [KO:K01047] [EC:3.1.1.4]
116946958  phospholipase A2 A2-actitoxin-Cgg2a-like [KO:K01047] [EC:3.1.1.4]
116946960  acidic phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
116940323  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
116946991  neutral phospholipase A2 3-like [KO:K01047] [EC:3.1.1.4]
116937493  acidic phospholipase A2 PL-I-like [KO:K01047] [EC:3.1.1.4]
116950958  group XIIA secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
116941294  PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
116944815  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
116955191  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
116953854  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
116958681  LOW QUALITY PROTEIN: phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
116944046  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
116952068  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
116958284  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
116946607  acyl-protein thioesterase 1-like isoform X1 [KO:K06128] [EC:3.1.1.5]
116941515  acyl-protein thioesterase 1-like [KO:K06128] [EC:3.1.1.5]
116944230  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
116944943  PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
116939640  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
116945026  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
116952632  ACHE; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
116939987  CHKB; choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
116951736  choline kinase alpha-like isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
116945527  choline kinase alpha-like isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
116956749  choline-phosphate cytidylyltransferase A-like [KO:K00968] [EC:2.7.7.15]
116957618  SELENOI; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
116956503  ethanolamine kinase 1-like [KO:K00894] [EC:2.7.1.82]
116937749  PCYT2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
116939643  phosphomethylethanolamine N-methyltransferase-like [KO:K05929] [EC:2.1.1.103]
116943248  phosphoethanolamine N-methyltransferase 3-like isoform X1 [KO:K05929] [EC:2.1.1.103]
116940190  ethanolamine-phosphate phospho-lyase-like isoform X1 [KO:K14286] [EC:4.2.3.2]
116946104  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
116940303  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
116950985  phosphatidate cytidylyltransferase 2-like isoform X1 [KO:K00981] [EC:2.7.7.41]
116948190  phospholipase A1 member A-like isoform X1 [KO:K13618] [EC:3.1.1.111]
116948191  phospholipase A1 member A-like isoform X1 [KO:K13618] [EC:3.1.1.111]
116951609  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
116945620  phosphatidylserine synthase 2-like [KO:K08730] [EC:2.7.8.29]
116939914  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
116958450  phosphatidylserine decarboxylase proenzyme, mitochondrial-like [KO:K01613] [EC:4.1.1.65]
116939049  phosphatidylserine decarboxylase proenzyme, mitochondrial-like isoform X1 [KO:K01613] [EC:4.1.1.65]
116947335  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
116952347  TAZ; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
116947167  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
116958413  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
116949678  MBOAT7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
pmrn00010  Glycolysis / Gluconeogenesis
pmrn00260  Glycine, serine and threonine metabolism
pmrn00561  Glycerolipid metabolism
pmrn00562  Inositol phosphate metabolism
pmrn00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
pmrn00565  Ether lipid metabolism
pmrn00620  Pyruvate metabolism
KO pathway
ko00564   
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