KEGG   PATHWAY: pss04814
Entry
pss04814                    Pathway                                
Name
Motor proteins - Pelodiscus sinensis (Chinese soft-shelled turtle)
Class
Cellular Processes; Cell motility
Pathway map
pss04814  Motor proteins
pss04814

Organism
Pelodiscus sinensis (Chinese soft-shelled turtle) [GN:pss]
Gene
102455866  DYNC1H1; LOW QUALITY PROTEIN: cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
102446759  DYNC2H1; LOW QUALITY PROTEIN: cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
102458333  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X2 [KO:K10415]
102449033  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
102459174  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
102463276  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 isoform X1 [KO:K10416]
102452537  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
102461373  DYNLL1; dynein light chain 1, cytoplasmic [KO:K10418]
102451636  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
102444554  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
102455266  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
102462401  DYNLT1; dynein light chain Tctex-type 1 isoform X2 [KO:K10420]
102452533  TCTEX1D4; tctex1 domain-containing protein 4 [KO:K25420]
102452642  TCTEX1D1; tctex1 domain-containing protein 1 [KO:K25421]
102444202  DNAH7; dynein heavy chain 7, axonemal isoform X1 [KO:K10408]
102459541  DNAH5; LOW QUALITY PROTEIN: dynein heavy chain 5, axonemal [KO:K10408]
102454921  DNAH6; dynein heavy chain 6, axonemal [KO:K10408]
102450071  DNAH11; LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal [KO:K10408]
102456809  DNAH12; dynein heavy chain 12, axonemal isoform X1 [KO:K10408]
102453836  DNAH8; dynein heavy chain 8, axonemal isoform X1 [KO:K10408]
102449919  DNAH10; LOW QUALITY PROTEIN: dynein heavy chain 10, axonemal [KO:K10408]
102446753  DNAH17; LOW QUALITY PROTEIN: dynein heavy chain 17, axonemal [KO:K10408]
102443889  DNAH14; dynein heavy chain 14, axonemal [KO:K10408]
102447295  dynein heavy chain 5, axonemal-like isoform X2 [KO:K10408]
102454423  DNAH9; dynein heavy chain 9, axonemal [KO:K10408]
102454792  DNAH1; dynein heavy chain 1, axonemal [KO:K10408]
102447635  dynein heavy chain 2, axonemal-like [KO:K10408]
102458657  LOW QUALITY PROTEIN: dynein heavy chain 9, axonemal-like [KO:K10408]
102445297  LOW QUALITY PROTEIN: dynein heavy chain 2, axonemal-like [KO:K10408]
102443900  DNAH3; dynein heavy chain 3, axonemal isoform X1 [KO:K10408]
102447674  DNAI1; dynein intermediate chain 1, axonemal [KO:K10409]
102456001  DNAI2; dynein intermediate chain 2, axonemal [KO:K11143]
102449834  WDR63; WD repeat-containing protein 63 isoform X2 [KO:K24722]
102453153  WDR78; WD repeat-containing protein 78 isoform X1 [KO:K24723]
102459427  DNALI1; axonemal dynein light intermediate polypeptide 1 [KO:K10410]
102448191  DNAL1; dynein light chain 1, axonemal isoform X1 [KO:K10411]
102448878  DNAL4; dynein light chain 4, axonemal [KO:K10412]
102455757  dynactin subunit 3-like [KO:K10425]
102450344  DCTN3; dynactin subunit 3 [KO:K10425]
102463790  DCTN4; LOW QUALITY PROTEIN: dynactin subunit 4 [KO:K10426]
102447571  DCTN5; dynactin subunit 5 [KO:K10427]
102457794  DCTN6; dynactin subunit 6 [KO:K10428]
102456627  ACTR1A; alpha-centractin isoform X1 [KO:K16575]
102444498  LOW QUALITY PROTEIN: beta-centractin [KO:K16575]
102459113  ACTR10; actin-related protein 10 [KO:K16576]
102463315  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
102447338  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
102449842  F-actin-capping protein subunit alpha-2-like isoform X1 [KO:K10364]
102453066  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
102455528  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
106732425  BICDL1; BICD family-like cargo adapter 1 [KO:K16756]
102452678  HOOK3; protein Hook homolog 3 isoform X2 [KO:K16536]
102457342  tubulin alpha-3 chain isoform X1 [KO:K07374]
102445223  tubulin alpha-3 chain-like [KO:K07374]
102446337  tubulin alpha-3 chain [KO:K07374]
102446572  tubulin alpha-3 chain-like isoform X3 [KO:K07374]
102445276  TUBA8; tubulin alpha-8 chain isoform X2 [KO:K07374]
102456974  TUBA1A; tubulin alpha-1A chain [KO:K07374]
102457222  tubulin alpha-1B chain [KO:K07374]
102457470  TUBA1C; tubulin alpha-1C chain [KO:K07374]
102450295  tubulin alpha-8 chain [KO:K07374]
102444792  tubulin alpha-4 chain [KO:K07374]
102455221  TUBB6; tubulin beta-6 chain isoform X1 [KO:K07375]
102456719  tubulin beta chain [KO:K07375]
102459913  TUBB3; LOW QUALITY PROTEIN: tubulin beta-3 chain [KO:K07375]
102451904  TUBB4A; tubulin beta-4A chain [KO:K07375]
102447709  TUBB1; tubulin beta-1 chain [KO:K07375]
102454956  tubulin beta-2 chain [KO:K07375]
102455457  tubulin beta-1 chain [KO:K07375]
102459003  TUBG1; tubulin gamma-1 chain [KO:K10389]
102459536  TUBD1; LOW QUALITY PROTEIN: tubulin delta chain [KO:K10390]
102444377  TUBE1; tubulin epsilon chain isoform X2 [KO:K10391]
102445070  KIF5B; kinesin-1 heavy chain isoform X2 [KO:K10396]
102456335  KIF5C; kinesin heavy chain [KO:K10396]
102443514  KLC2; LOW QUALITY PROTEIN: kinesin light chain 2 [KO:K10407]
102456363  KLC1; kinesin light chain 1 isoform X6 [KO:K10407]
102453022  kinesin light chain 1 [KO:K10407]
102447766  KIF3A; LOW QUALITY PROTEIN: kinesin-like protein KIF3A [KO:K10394]
102463259  KIF3B; kinesin-like protein KIF3B [KO:K20196]
102446811  KIFAP3; LOW QUALITY PROTEIN: kinesin-associated protein 3 [KO:K25388]
102454786  KIF1A; kinesin-like protein KIF1A isoform X1 [KO:K10392]
102455485  KIF1B; kinesin-like protein KIF1B isoform X5 [KO:K10392]
102461040  KIF1C; LOW QUALITY PROTEIN: kinesin-like protein KIF1C [KO:K10392]
102451472  KIF13B; kinesin-like protein KIF13B isoform X1 [KO:K17914]
102443397  KIF13A; kinesin-like protein KIF13A isoform X1 [KO:K17914]
102449490  KIF14; kinesin-like protein KIF14 isoform X1 [KO:K17915]
102450461  KIF16B; kinesin-like protein KIF16B isoform X5 [KO:K17916]
102451938  STARD9; stAR-related lipid transfer protein 9 [KO:K16491]
102447634  KIF4A; chromosome-associated kinesin KIF4A isoform X1 [KO:K10395]
102456695  KIF7; LOW QUALITY PROTEIN: kinesin-like protein KIF7 [KO:K18806]
102463234  KIF21A; kinesin-like protein KIF21A isoform X1 [KO:K24185]
102454116  KIF21B; kinesin-like protein KIF21B [KO:K24185]
102460392  KIF27; kinesin-like protein KIF27 isoform X1 [KO:K24186]
102452697  KIF11; kinesin-like protein KIF11 [KO:K10398]
102453741  KIF20B; kinesin-like protein KIF20B isoform X1 [KO:K10402]
102456038  KIF20A; kinesin-like protein KIF20A isoform X1 [KO:K10402]
102446292  kinesin-like protein KIF20A [KO:K10402]
102454486  KIF23; kinesin-like protein KIF23 [KO:K17387]
102459084  CENPE; centromere-associated protein E [KO:K11498]
102446637  KIF18A; kinesin-like protein KIF18A isoform X1 [KO:K10401]
102443372  KIF19; kinesin-like protein KIF19 [KO:K26157]
102461204  KIF9; kinesin-like protein KIF9 isoform X1 [KO:K10397]
102454728  KIF6; kinesin-like protein KIF6 isoform X1 [KO:K10397]
102449789  KIF22; LOW QUALITY PROTEIN: kinesin-like protein KIF22 [KO:K10403]
102459850  KIF26A; LOW QUALITY PROTEIN: kinesin-like protein KIF26A [KO:K10404]
102450990  KIF26B; LOW QUALITY PROTEIN: kinesin-like protein KIF26B [KO:K10404]
102449182  KIF15; kinesin-like protein KIF15 [KO:K10400]
102448814  KIF24; kinesin-like protein KIF24 isoform X1 [KO:K10393]
102450601  KIF2C; kinesin-like protein KIF2C [KO:K10393]
102455355  KIF2A; kinesin-like protein KIF2A isoform X1 [KO:K10393]
102448128  KIFC1; kinesin-like protein KIFC1 isoform X1 [KO:K10405]
102445510  KIFC3; kinesin-like protein KIFC3 isoform X1 [KO:K10406]
102454461  KIF25; kinesin-like protein KIF25 isoform X1 [KO:K18627]
102444167  MYO1D; LOW QUALITY PROTEIN: unconventional myosin-Id [KO:K10356]
102463545  MYO1B; unconventional myosin-Ib isoform X1 [KO:K10356]
102461036  unconventional myosin-Ie-like [KO:K10356]
102448731  unconventional myosin-If [KO:K10356]
102462607  MYO1H; unconventional myosin-Ih [KO:K10356]
102463823  MYO1C; unconventional myosin-Ic isoform X1 [KO:K10356]
102455620  MYO1E; unconventional myosin-Ie [KO:K10356]
102449349  MYO3A; myosin-IIIa isoform X2 [KO:K08834] [EC:2.7.11.1]
102451728  MYO3B; myosin-IIIb [KO:K08834] [EC:2.7.11.1]
102455112  MYO5B; LOW QUALITY PROTEIN: unconventional myosin-Vb [KO:K10357]
102446200  MYO5A; unconventional myosin-Va [KO:K10357]
102444310  unconventional myosin-Vb-like [KO:K10357]
102447990  MYO5C; unconventional myosin-Vc [KO:K10357]
102443927  MYO6; unconventional myosin-VI isoform X2 [KO:K10358]
102461293  LOW QUALITY PROTEIN: unconventional myosin-VIIa [KO:K10359]
102460220  MYO7B; LOW QUALITY PROTEIN: unconventional myosin-VIIb [KO:K21868]
102456058  MYO9A; LOW QUALITY PROTEIN: unconventional myosin-IXa [KO:K10360]
102457797  MYO9B; unconventional myosin-IXb isoform X1 [KO:K10360]
102447238  unconventional myosin-X-like [KO:K12559]
102447795  MYO10; unconventional myosin-X [KO:K12559]
102444056  unconventional myosin-XVI-like [KO:K17481]
102455319  unconventional myosin-XVIIIb-like [KO:K10362]
102455778  MYO19; unconventional myosin-XIX [KO:K25838]
102446383  myosin-1B-like [KO:K24220]
102445983  myosin-1B [KO:K24220]
102457095  MYH15; myosin-15 isoform X2 [KO:K24220]
102460172  MYH7B; LOW QUALITY PROTEIN: myosin-7B [KO:K24220]
102450688  LOW QUALITY PROTEIN: myosin-7 [KO:K17751]
102455980  LOW QUALITY PROTEIN: myosin-7-like [KO:K17751]
102451385  MYH10; myosin-10 isoform X2 [KO:K10352]
102448129  MYH9; myosin-9 [KO:K10352]
102445883  MYH11; LOW QUALITY PROTEIN: myosin-11 [KO:K10352]
102447431  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
102460214  MYL3; myosin light chain 3 [KO:K12749]
102453002  MYL4; myosin light chain 4 isoform X2 [KO:K12750]
102455654  myosin light polypeptide 6 [KO:K12751]
102455412  myosin light chain 6B [KO:K12751]
102449621  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
102457241  MYL5; myosin light chain 5 [KO:K12753]
102457458  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
102445169  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
102456345  MYL10; myosin regulatory light chain 10 [KO:K12756]
102457934  myosin regulatory light chain 2, smooth muscle minor isoform-like isoform X2 [KO:K12757]
102459140  myosin regulatory light polypeptide 9 [KO:K12757]
102457840  myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
102446120  ACTA1; actin, alpha skeletal muscle [KO:K10354]
102446709  actin, cytoplasmic 1-like [KO:K10354]
102456465  ACTA2; actin, aortic smooth muscle [KO:K12313]
102456632  actin, alpha cardiac muscle 1 [KO:K12314]
102450720  actin, aortic smooth muscle-like [KO:K12314]
102449143  ACTG2; actin, gamma-enteric smooth muscle [KO:K12315]
102453465  actin, cytoplasmic 2 [KO:K05692]
102458214  actin, cytoplasmic type 5 isoform X2 [KO:K05692]
102451064  ACTB; actin, cytoplasmic 1 [KO:K05692]
102457924  ACTL8; LOW QUALITY PROTEIN: actin-like protein 8 [KO:K05692]
102458464  actin, cytoplasmic type 5 [KO:K05692]
102458697  TNNC1; troponin C, slow skeletal and cardiac muscles isoform X1 [KO:K05865]
102458504  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
102460124  troponin T, slow skeletal muscle-like [KO:K10372]
102447463  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
102445855  TNNT3; troponin T, fast skeletal muscle isoform X1 [KO:K12046]
102457508  TNNT2; troponin T, cardiac muscle isoform X1 [KO:K12045]
102458138  TPM1; tropomyosin alpha-1 chain [KO:K10373]
102464093  tropomyosin beta chain-like [KO:K10374]
102457475  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
102456979  tropomyosin alpha-1 chain [KO:K10375]
Reference
PMID:21092854
  Authors
Hirokawa N, Niwa S, Tanaka Y
  Title
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.
  Journal
Neuron 68:610-38 (2010)
DOI:10.1016/j.neuron.2010.09.039
Reference
PMID:25470043 (PDB:4RH7)
  Authors
Schmidt H, Zalyte R, Urnavicius L, Carter AP
  Title
Structure of human cytoplasmic dynein-2 primed for its power stroke.
  Journal
Nature 518:435-438 (2015)
DOI:10.1038/nature14023
Reference
PMID:22398446 (PDB:3VKG 3VKH)
  Authors
Kon T, Oyama T, Shimo-Kon R, Imamula K, Shima T, Sutoh K, Kurisu G
  Title
The 2.8 A crystal structure of the dynein motor domain.
  Journal
Nature 484:345-50 (2012)
DOI:10.1038/nature10955
Reference
PMID:22997337 (PDB:3J1T 3J1U)
  Authors
Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE
  Title
Structural basis for microtubule binding and release by dynein.
  Journal
Science 337:1532-1536 (2012)
DOI:10.1126/science.1224151
Reference
PMID:26410600
  Authors
Gibbs KL, Greensmith L, Schiavo G
  Title
Regulation of Axonal Transport by Protein Kinases.
  Journal
Trends Biochem Sci 40:597-610 (2015)
DOI:10.1016/j.tibs.2015.08.003
Reference
PMID:28602352 (PDB:5NUG 5NVS 5NVU 5NW4)
  Authors
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
  Title
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
  Journal
Cell 169:1303-1314.e18 (2017)
DOI:10.1016/j.cell.2017.05.025
Reference
PMID:25814576 (PDB:5ADX 5AFR 5AFU)
  Authors
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
  Title
The structure of the dynactin complex and its interaction with dynein.
  Journal
Science 347:1441-1446 (2015)
DOI:10.1126/science.aaa4080
Reference
PMID:29420470 (PDB:5OWO 6F1T 6F1U 6F1V 6F1Y 6F1Z 6F38 6F3A)
  Authors
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
  Title
Cryo-EM shows how dynactin recruits two dyneins for faster movement.
  Journal
Nature 554:202-206 (2018)
DOI:10.1038/nature25462
Reference
PMID:29662141
  Authors
Reck-Peterson SL, Redwine WB, Vale RD, Carter AP
  Title
The cytoplasmic dynein transport machinery and its many cargoes.
  Journal
Nat Rev Mol Cell Biol 19:382-398 (2018)
DOI:10.1038/s41580-018-0004-3
Reference
PMID:23434508 (PDB:3J2U)
  Authors
Asenjo AB, Chatterjee C, Tan D, DePaoli V, Rice WJ, Diaz-Avalos R, Silvestry M, Sosa H
  Title
Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.
  Journal
Cell Rep 3:759-68 (2013)
DOI:10.1016/j.celrep.2013.01.030
Reference
PMID:10338210 (PDB:1B7T)
  Authors
Houdusse A, Kalabokis VN, Himmel D, Szent-Gyorgyi AG, Cohen C
  Title
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
  Journal
Cell 97:459-70 (1999)
DOI:10.1016/s0092-8674(00)80756-4
Reference
PMID:9428521 (PDB:3KIN)
  Authors
Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E
  Title
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility.
  Journal
Cell 91:985-94 (1997)
DOI:10.1016/s0092-8674(00)80489-4
Reference
PMID:8316857 (PDB:2MYS)
  Authors
Rayment I, Rypniewski WR, Schmidt-Base K, Smith R, Tomchick DR, Benning MM, Winkelmann DA, Wesenberg G, Holden HM
  Title
Three-dimensional structure of myosin subfragment-1: a molecular motor.
  Journal
Science 261:50-8 (1993)
DOI:10.1126/science.8316857
Reference
PMID:20428469
  Authors
Parker D, Bryant Z, Delp SL
  Title
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics.
  Journal
Cell Mol Bioeng 2:366-374 (2009)
DOI:10.1007/s12195-009-0084-4
Reference
PMID:21314430
  Authors
Dominguez R, Holmes KC
  Title
Actin structure and function.
  Journal
Annu Rev Biophys 40:169-86 (2011)
DOI:10.1146/annurev-biophys-042910-155359
Reference
PMID:31919429 (PDB:6KN7 6KN8)
  Authors
Yamada Y, Namba K, Fujii T
  Title
Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
  Journal
Nat Commun 11:153 (2020)
DOI:10.1038/s41467-019-14008-1
Reference
PMID:33912943
  Authors
Kruppa AJ, Buss F
  Title
Motor proteins at the mitochondria-cytoskeleton interface.
  Journal
J Cell Sci 134:239092 (2021)
DOI:10.1242/jcs.226084
KO pathway
ko04814   
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